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      learn Finasteride

      Popular 5-alpha reductase inhibitor that lowers DHT, taken as a pill or used topically
      • Is finasteride safe? In one-year trials most men tolerated finasteride 1 mg, but its risks are not only sexual: US, UK and EU regulators warn of sexual dysfunction, depression and suicidal thoughts, and of sexual and mood symptoms that have continued after stopping, and men also report cognitive, anxiety and physical symptoms. How often lasting problems happen, and how much of that the drug causes, is not known; finasteride is prescription-only and must not be taken, or handled as crushed or broken tablets, by women who are or may be pregnant.
      • Finasteride Results Timeline: How Long It Takes to Work, Shedding Phases, and Expected Outcomes Trial data and community reports both put the first visible changes on finasteride at roughly 3 to 6 months, with the clearest results between 6 and 12 months; some people report an early increase in shedding, but how often this happens has not been measured. The benefit lasts only while the drug is taken, it is prescription-only, and its labels warn of sexual side effects that have continued after stopping in some men, of depression and suicidal thoughts, and of breast and semen changes; some former users also report anxiety and cognitive complaints (see "Is finasteride safe?").

      learn Dutasteride

      5-alpha reductase inhibitor that blocks both enzyme types, a stronger DHT blocker than finasteride