6 citations
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June 1994 in “Journal of Animal Science” This study found that none of the depigmenting compounds tested in beef heifers produced a permanent depigmenting effect, though visible depigmentation lasted up to 3 months.
November 2022 in “Journal of Investigative Dermatology” This study developed a chalcone-based molecule that significantly increased tyrosinase inhibition and solubility, showing potential as a safe and effective skin depigmenting and antiaging agent, with supportive epigenetic and antioxidant properties observed in vitro.
7 citations
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March 1990 in “Pigment Cell Research” This animal study observed that while topical MBEH and intraperitoneal phenol induced hair graying in eumelanic mice, they had little effect on pheomelanic mice, and amcinonide reduced certain epidermal melanocytes in both.
July 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” This study by Refat et al. found that the level of CD8+ T cell infiltrates in vitiligo lesions before surgical treatment can predict the likelihood of successful repigmentation, suggesting a potential new method for identifying patients who may benefit the most from surgical interventions.
11 citations
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August 1987 in “Archives of Dermatology” In this study, researchers found that Langerhans' cells likely do not play a role in the depigmentation process in C57Bl/Ler-vit.vit mice, as their number was normal during depigmentation and highest afterward.