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research Expression, characterization, and structural analysis of human liver delta4-3-ketosteroid 5beta-reductase (AKR1D1) and its disease-related mutant P133R

January 2009 in “ScholarlyCommons (University of Pennsylvania)”

This study provided the first X-ray crystal structure of the mammalian steroid hormone reductase AKR1D1 and identified a disease-related mutant, P133R, which may impact bile acid metabolism and cause clinical symptoms.

research Differential dependency of unmyelinated and A delta epidermal and upper dermal innervation on neurotrophins, trk receptors, and p75LNGFR.

122 citations , June 1998 in “PubMed”

This study found that sensory and sympathetic innervation in the mystacial pads of mice is governed by a balance of neurotrophin signaling, highlighting the roles of NGF/trkA and NT-3/trkC pathways.

research Clinical, ultrasound and hormonal markers of androgenicity in acne vulgaris

57 citations , August 1995 in “British Journal of Dermatology”

In this study, acne severity in females was strongly associated with inflammatory lesion count and moderately associated with androgens, especially DELTA 4 and DHEAS promoting acne and SHBG reducing it.

Testicular Steroidogenesis: Production and Regulation of Testosterone and Dihydrotestosterone

research Testicular Steroidogenesis

5 citations , January 2017 in “Endocrinology”

This chapter reviews the biosynthesis, mechanism of action, and therapeutic effects of testosterone and related androgens, but reports no new research findings.

An Adult With Hair Loss: A Rare Case of Non-Classical 3β Hydroxysteroid Dehydrogenase Deficiency

research An Adult With Hair Loss! a Rare Case of Non-Classical 3β Hydroxysteroid Dehydrogenase (3β HSD) Deficiency

May 2021 in “Journal of the Endocrine Society”

This report presents a rare case of suspected 3β HSD deficiency in an adult female with symptoms like male pattern hair loss and low testosterone, suggesting a non-classical presentation.

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Learn

1 / 801 results

learn Scalp Micropigmentation

How much does scalp micropigmentation cost? Scalp micropigmentation typically costs between $1,000 and $5,000 depending on individual needs.
When will I see results from scalp micropigmentation? Initial results from scalp micropigmentation may appear in 3-4 months, with full results taking up to 18 months.
What should I do before my scalp micropigmentation appointment? Most providers ask clients to skip alcohol and caffeine, and to avoid over-the-counter blood thinners, for 24-48 hours. Never stop a prescribed blood thinner without your doctor's approval.

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Clinics

1 / 143 results

33
Hair Systems
Maverick Delta StudioBrighton, England · GB

Community Join

5 / 27 results

community Il PP405 è molto promettente ma non è l'unico in grado di liberarci dalla iattura

3 upvotes 1 year ago

PP405 shows promise in hair loss treatment, but stem cell therapy using adipose-derived stem cells and ATP also successfully reversed androgenetic alopecia in mice. Stem cell therapy is costly, and some doubt the effectiveness of PP405 based on press releases.

community I cannot even tolerate Nutrafol

in Product 6 upvotes 10 months ago

The user experienced side effects from finasteride and Nutrafol, opting for non-hormonal treatments like minoxidil, exercise, and a healthy lifestyle. Others discussed using Dutasteride, Biotin, and minoxidil with varying success and side effects.

community Weed/THC effects on hair growth/hair loss, and vitality of organ-culture human follicle studies (research review)

4 upvotes 1 year ago

Cannabis and THC may have mixed effects on hair, with some studies suggesting potential negative impacts on hair growth in isolated hair follicles, but these results are hard to apply to living humans. Treatments like minoxidil and finasteride are commonly used for hair loss, and the effects of cannabis might be neutral or vary based on individual factors.

community Update: going nuclear! (Switch to dut)

in Update 13 upvotes 5 months ago

The user had a hair transplant in March 2025 and has been using finasteride since 2023, which halted hair loss but didn't fully restore density. They plan to use dutasteride twice weekly, finasteride five times a week, and saw palmetto to improve hair thickness.

community Guys where do I find a legit source for this? Anyone try it?

in Treatment 14 upvotes 8 months ago

The conversation discusses hair loss treatments, focusing on the use of peptides, injections, and topical applications like Minoxidil foam. Users debate the effectiveness of different methods, with some advocating for injections and others supporting topical treatments.

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