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GlossaryTyrosinase-Related Protein 2 (DCT)

enzyme crucial for melanin production in hair and skin

Tyrosinase-Related Protein 2 (TRP-2), also known as Dopachrome Tautomerase (DCT), is an enzyme involved in the production of melanin, the pigment responsible for hair, skin, and eye color. It plays a crucial role in the melanin biosynthesis pathway by converting dopachrome into dihydroxyindole-2-carboxylic acid (DHICA), which helps determine the type and amount of melanin produced. This protein is significant in studies related to pigmentation disorders and melanoma.

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research Epicardial Fat Thickness in Children with Classic Congenital Adrenal Hyperplasia

October 2018 in “Journal of Clinical Research in Pediatric Endocrinology”

Children with classic congenital adrenal hyperplasia have thicker heart fat and more heart and blood vessel risk factors, especially if their condition is not well-controlled.

research Sox2 in the Dermal Papilla Regulates Hair Follicle Pigmentation

9 citations , July 2022 in “Cell reports”

Sox2 controls hair color by affecting pigment production in hair follicles.

research Epicardial Fat Thickness in Children with Classic Congenital Adrenal Hyperplasia

9 citations , February 2019 in “Journal of Clinical Research in Pediatric Endocrinology”

Children with classic congenital adrenal hyperplasia have thicker heart fat and are at higher risk for heart problems and early atherosclerosis.

research Differentiation of CD34+ Human Hair Follicle Stem Cells into Functional Melanocytes

1 citations , December 2018 in “IOP conference series. Materials science and engineering”

CD34+ hair follicle stem cells can become melanin-producing cells for treating skin conditions.

research Valorization of Hom Thong Banana Peel (Musa sp., AAA Group) as an Anti-Melanogenic Agent Through Inhibition of Pigmentary Genes and Molecular Docking Study

4 citations , December 2024 in “International Journal of Molecular Sciences”

Hom Thong banana peels can help reduce skin pigmentation by inhibiting melanin production.

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