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GlossaryCyclophosphamide (Cytoxan)

chemotherapy drug that interferes with DNA replication in cells

Cyclophosphamide, also known as Cytoxan, is a chemotherapy drug used to treat various types of cancer and certain autoimmune diseases. It works by interfering with the DNA replication process in rapidly dividing cells, which helps to slow or stop the growth of cancer cells. However, it can also affect healthy cells, leading to side effects such as hair loss (alopecia) and increased risk of infections.

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Cystitis Due to Cytoxan: Case Report

research Cystitis Due to Cytoxan: Case Report

15 citations, May 1966 in “The Journal of Urology”

A woman developed severe bladder inflammation after cancer treatment with Cytoxan.

Vitamin D3 and Chemotherapy-Induced Alopecia

research Vitamin D3 and Chemotherapy-Induced Alopecia

11 citations, June 1996 in “Nutrition”

Vitamin D3 may prevent hair loss from chemotherapy, but side effects and cancer cell protection are concerns.

The Role of Platelet-Rich Plasma in the Prevention of Chemotherapy-Induced Alopecia

research The Role of Platelet-Rich Plasma in the Prevention of Chemotherapy-Induced Alopecia

2 citations, November 2019 in “Skin appendage disorders”

Platelet-rich plasma doesn't prevent hair loss from chemotherapy, and mononuclear cells only help against hair loss from one specific chemotherapy drug.

research Immunosuppressive Treatment for Proliferative Lupus Nephritis

86 citations, June 2018 in “Cochrane library”

Mycophenolate mofetil may improve lupus nephritis remission more than cyclophosphamide but with uncertain safety.

research Clinical Presentation and Management Outcome of Childhood-Onset Systemic Lupus Erythematosus in Baghdad

13 citations, May 2014 in “PubMed”

Most children with childhood-onset lupus in Baghdad responded well to treatment, but some developed chronic kidney disease or died.

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