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GlossaryCytotoxicity (Cytotoxic Effects)

quality of being toxic to cells, often used in cancer treatment

Cytotoxicity refers to the quality of being toxic to cells. It describes the ability of certain substances or treatments, such as chemotherapy drugs, to kill or damage cells. This property is crucial in cancer treatment, where the goal is to target and destroy cancerous cells while minimizing harm to healthy cells.

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Multiple Readout Assay for Hormonal (Androgenic and Antiandrogenic) and Cytotoxic Activity of Plant and Fungal Extracts Based on Differential Prostate Cancer Cell Line Behavior

research Multiple Readout Assay for Hormonal (Androgenic and Antiandrogenic) and Cytotoxic Activity of Plant and Fungal Extracts Based on Differential Prostate Cancer Cell Line Behavior

19 citations, August 2014 in “Journal of Ethnopharmacology”

The study created a test that found hormonal and toxic effects in plant and fungal extracts using prostate cancer cells.

research Biphasic Effects of Minoxidil on the Proliferation and Differentiation of Normal Human Keratinocytes

34 citations, January 1997 in “Skin Pharmacology and Physiology”

Minoxidil affects cell growth in two ways: low doses increase growth, while high doses slow it down and can be toxic.

research Regulatory Effects of Thai Rice By-Product Extracts from Oryza Sativa L. Cv. Bue Bang 3 CMU and Bue Bang 4 CMU on Melanin Production, Nitric Oxide Secretion, and Steroid 5α-Reductase Inhibition

1 citations, February 2023 in “Plants”

BB4CMU rice bran oil may help treat hair loss and gray hair.

research Anti-Androgen Effects of Extracts and Compounds from Ganoderma Lucidum

20 citations, February 2009 in “Chemistry & Biodiversity”

Ganoderma lucidum may help treat prostate cancer by blocking male hormones and slowing cancer cell growth.

research Novel Synthesis of Nicotinamide Derivatives with Cytotoxic Properties

51 citations, March 2006 in “Bioorganic & Medicinal Chemistry”

Newly made nicotinamide compounds could potentially treat cancer.

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community I started rapidly diffuse thinning at 22. I'm 42 now and have as much hair as I did at 16. AMA

in Treatment 449 upvotes 4 years ago

Hair loss treatments like finasteride, minoxidil, ketoconazole, PRP, and microneedling helped maintain hair for 20 years. Research and try evidence-based treatments for best results.

community If you’re sitting there wondering, “I’m losing my hair, what do I do?” then read my advice here. I’ve been fighting the fight for 7 years, with great success. (pictures included)

in Question 106 upvotes 11 years ago

Fighting hair loss with "The Big 3" treatments of Propecia, Rogaine and Nizoral shampoo, as well as specific advice on how to use these products. People have shared their long-term success stories and some have discussed the side effects of finasteride. Other suggestions included Lipogaine and Pura D'or Hair Loss Prevention Therapy Shampoo & Conditioner.

community Switched from finasteride to dutasteride - 2 month update

in Finasteride/Dutasteride 6 upvotes 11 months ago

The user switched from finasteride to dutasteride for hair loss treatment, but experienced increased libido, itchy scalp, and accelerated hair loss. Another user suggested that genetic variations might cause dutasteride to be less effective and recommended checking for specific genetic markers.

community A meta analysis of 18 popular hair loss treatments. An 2022 guide on efficacy. From finasteride and minoxidil to caffeine shampoo, saw palmetto and biotin. 96 Scientific References included.

in Research/Science 102 upvotes 2 years ago

Most hair loss treatments are ineffective; only finasteride, dutasteride, and minoxidil show effectiveness.

community Alfatradiol to combat hair loss

6 upvotes 10 years ago

Hair loss discussion includes treatments Minoxidil, Finasteride, and RU58841. Alfatradiol is suggested as another potential solution.