3 citations
,
July 2015 in “European Journal of Dermatology”
This abstract discusses the role of advanced glycation end-products in aging-related skin damage, but does not provide new findings on their impact on alopecia.
This study suggests that keratinocytes derived from hair follicles of patients with atopic dermatitis provide a useful model for investigating AD-related inflammation, as they showed greater expression changes of AD markers when stimulated with type 2 cytokines compared to those from healthy donors.
5 citations
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January 2022 in “Molecular Medicine Reports”
In this study, topical application of Korean maritime pine bark extract at 2% concentration significantly promoted hair growth in mice, suggesting its potential use for hair loss prevention or treatment.
This study found that applying AGN root extract containing decursin to mouse skin accelerated hair growth and altered inflammatory cytokine levels compared to a control.
COVID and COVID vaccination can trigger hair loss, primarily telogen effluvium, due to stress and immune system activation. Proper diagnosis and addressing factors like nutrition and stress are crucial for recovery.
Creatine may increase scalp DHT without affecting serum DHT, potentially speeding up male pattern baldness (MPB) for those genetically prone. Treatments mentioned include Minoxidil, finasteride, and RU58841.
Dutasteride at 0.5 mg/day does not significantly alter allopregnanolone levels, but higher doses (2.5 mg/day) do. Dutasteride may also have anti-neuroinflammatory effects, but the impact on neurosteroids is still debated.
Subcutaneous scalp fat may be linked to hair loss, with theories suggesting that fat loss can lead to reduced blood flow and increased DHT activity, contributing to hair loss. Treatments discussed include PRP/PRF injections and fat transfer to improve scalp thickness and blood flow.
Microneedling for hair restoration involves daily use of a 0.3 mm device and weekly use of a 0.5 mm device. Combining microneedling with Minoxidil can enhance hair growth.