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5 / 5 resultslearn Neem Oil
natural substance from Neem tree with medicinal and pesticidal properties
learn Osteopontin
signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss
learn Procyanidin
bioflavonoid found in plants with antioxidant and hair stimulating properties
learn Alopecia Areata
autoimmune disorder causing patchy hair loss
Research
5 / 1000+ resultsresearch Langerin+ Dendritic Cells In Cutaneous Fibrosis: The TGF-β1 Signaling Axis
Cutaneous fibrosis, such as hypertrophic scars and keloids, occurs when immune, epithelial, and stromal signals fail to balance after injury. Langerin+ dendritic cells (DCs) play a central role by producing latent TGF-β1, which is activated by keratinocyte integrins, forming a "cytokine gate" that can lead to fibrosis if overstimulated. Active TGF-β1, along with YAP/TAZ, promotes fibroblast activation and matrix stiffening, while immune responses maintain a pro-fibrotic environment. The study explores the interaction between epithelial integrins, DCs, and fibroblast mechanotransduction, comparing normal wound healing with fibrosis, and suggests therapeutic strategies targeting the αv integrin-TGF-β1 axis, YAP/TAZ, and immune signals. This DC-focused perspective offers new hypotheses and potential for mechanism-based therapies.
research Cytokine Loaded Layer-By-Layer Ultrathin Matrices to Deliver Single Dermal Papilla Cells for Spot-By-Spot Hair Follicle Regeneration
Scientists have created a method to deliver specific cells that can regenerate hair follicles, potentially offering a new treatment for hair loss.
research Selective Expansion of Tregs Using the IL-2 Cytokine Antibody Complex Does Not Reverse Established Alopecia Areata in C3H/HeJ Mice
Increasing Treg cells in the skin does not cure hair loss from alopecia areata in mice.
research Age-Associated Inflammation Inhibits Epidermal Stem Cell Function
Aging causes skin stem cells to work less effectively.
research The Role of Lymphocytes in the Development and Treatment of Alopecia Areata
Lymphocytes, especially CD8+ T cells, play a key role in causing alopecia areata, and targeting them may lead to new treatments.
Community Join
5 / 33 resultscommunity My Theory Of Androgenic Alopecia
Hair loss is linked to cellular physiology and the IGF-1 to TGF-B1 ratio, not just androgen sensitivity. The theory lacks evidence, while finasteride and minoxidil are effective treatments.
community Hair loss after COVID or vaccination isn’t “made up” but it’s also not what TikTok makes it sound like
COVID and COVID vaccination can trigger hair loss, primarily telogen effluvium, due to stress and immune system activation. Proper diagnosis and addressing factors like nutrition and stress are crucial for recovery.
community Hair Loss “Cure” for Inflammation: Topical Roflumilast
Topical roflumilast is effective for reducing inflammation in various scalp conditions like seborrheic dermatitis, psoriasis, and eczema, but not proven to stop scarring alopecia. Alternatives like apremilast and Vtama are also discussed for their anti-inflammatory benefits.
community Prolactin’s role in antitumor activity of the immune system – a safety concern for HMI-115?
Hair loss discussion includes treatments Minoxidil, Finasteride, and RU58841. Prolactin's role in immune system's antitumor activity raises safety concerns for HMI-115.
community My derm said they came up with a new serum that is better then fin? What’s y’all’s thoughts
A new serum claims to enhance hair regrowth by amplifying oxygen delivery, improving the effectiveness of treatments like exosomes and peptides. Users are skeptical, questioning its efficacy compared to established treatments like Minoxidil and Finasteride.