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Controlled Clinical Trial for Evaluation of Hair Growth with Low Dose Cyclical Nutrition Therapy in Men and Women Without the Use of Finasteride

research Controlled clinical trial for evaluation of hair growth with low dose cyclical nutrition therapy in men and women without the use of finasteride

5 citations , September 2017 in “Plastic and Aesthetic Research”

This study aimed to assess whether using minoxidil alongside nutritional cyclical supplements could boost hair regrowth without antiandrogens or enzyme blockers, focusing on hair root strengthening. Results are not reported.

research Effective medical treatment for common baldness in women

43 citations , July 1984 in “Clinical and Experimental Dermatology”

This study found that women with common baldness treated with cyclical antiandrogen therapy for 52 weeks experienced increased hair density and a higher percentage of hairs in the anagen growth phase.

research S127 Regulation of hair growth

September 1997 in “JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology”

The document concludes that treatments like oral anti-androgens, minoxidil, and topical spironolactone can be effective for hair loss in men and women.

research Spironolactone is an Effective and Well Tolerated Systemic Antiandrogen Therapy for Hirsute Women*

78 citations , May 1989 in “The Journal of Clinical Endocrinology & Metabolism”

This study found that in hirsute women, daily treatment with 200 mg spironolactone significantly reduced hair growth rates and hair shaft diameters on various body areas over 12 months.

research Anti-Androgen Therapy in Female Adult Acne

4 citations , April 2016 in “Journal of Dermatology Research and Therapy”

This article discusses the multifactorial nature of acne vulgaris, detailing its link to androgen-induced sebum production, altered keratinisation, inflammation, and bacterial colonisation, but reports no new research findings.

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Community Join

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community Derm stopped me from using Minoxidal

in Update 55 upvotes 10 months ago

A dermatologist advised stopping minoxidil due to heavy shedding, suggesting alternative treatments like Betaval Lotion and supplements, but many users disagreed, recommending continuing minoxidil and adding finasteride for better results. The conversation highlights skepticism about the dermatologist's motives and emphasizes the importance of understanding the type of hair loss before choosing treatments.

community 2 years fin only 1mg/daily + 4 months of gradually introducing Dut 0.5mg/daily

1706 upvotes 1 year ago

A user experienced significant hair regrowth using finasteride 1 mg daily for two years and gradually introduced dutasteride 0.5 mg daily over four months. They reported no side effects and plan to switch fully to dutasteride due to its cost-effectiveness and potential effectiveness.

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Learn

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learn Cyproterone

a synthetic anti-androgen and weak progestogen that inhibits DHT binding to androgen receptor

Is cyproterone safe to use during gender transition? Regulators and a large French cohort study link higher-dose, long-term cyproterone acetate to meningioma, and its label also lists liver-enzyme and mood effects — so it is not a drug anyone should call safe in the abstract, and its use in gender-affirming care is a prescriber's decision with monitoring.

learn Pyrilutamide

highly targeted anti-androgen that might have minimal systemic effects

learn Bicalutamide

a nonsteroidal anti-androgen, most commonly used orally for women

Can bicalutamide stop DHT from shrinking your hair follicles? Bicalutamide blocks androgens at the receptor rather than lowering DHT, and some dermatologists prescribe it off-label for women with pattern hair loss. The published evidence is retrospective case series and one small pilot study, with no randomized trial; it is a prescription drug that requires liver monitoring and is contraindicated in pregnancy.
Why are some women using bicalutamide to fight hormonal hair loss? Bicalutamide blocks androgens, helping women combat hormonal hair loss effectively.

learn Clascoterone

a novel topical treatment that inhibits DHT on androgen receptors

Can I use clascoterone if I'm undergoing gender-affirming hormone therapy? No published clinical trial has tested clascoterone in people on gender-affirming hormone therapy, so its safety in that group is unknown. The FDA label reports low systemic exposure and no described effect on blood testosterone, but it also records HPA-axis suppression and raised potassium in a small minority of subjects.

learn RU58841

a potent but unapproved and potentially problematic topical anti-androgen

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