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research Interaction of Alpha-Melanocyte-Stimulating Hormone, Melatonin, Cyclic AMP and Cyclic GMP in the Control of Melanogenesis in Hair Follicle Melanocytes In Vitro

53 citations , July 1981 in “Journal of Endocrinology”

α-MSH and cyclic AMP boost melanin production, while cyclic GMP and melatonin reduce it.

research Cyclic Nucleotides and the Mediation of Melatonin-Induced Inhibition of Melanogenesis in Mammals

1 citations , January 1981 in “Elsevier eBooks”

Melatonin stops melanin production after tyrosinase action, with cyclic GMP mimicking this effect.

research The Action of Diazoxide and Minoxidil Sulphate on Rat Blood Vessels: A Comparison with Cromakalim

86 citations , July 1990 in “British Journal of Pharmacology”

Diazoxide, minoxidil sulphate, and cromakalim relax rat blood vessels by opening K+ channels, with some differences in their actions.

research Characterization of Novel TMEM173 Mutation Causing a Lupus- and SAVI-Like Phenotype, Modified by Polymorphisms in TMEM173 and IFIH1

September 2019 in “The journal of investigative dermatology/Journal of investigative dermatology”

A new mutation in the STING protein causes a disease with lupus-like symptoms and responds well to a specific inhibitor treatment.

research Aberrant Inflammasome Activation as a Driving Force of Human Autoimmune Skin Disease

3 citations , May 2023 in “Frontiers in immunology”

Faulty inflammasome activation may lead to autoimmune skin diseases and could be a target for new treatments.

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community Hair Loss “Cure” for Inflammation: Topical Roflumilast

in Research/Science 32 upvotes 2 months ago

Topical roflumilast is effective for reducing inflammation in various scalp conditions like seborrheic dermatitis, psoriasis, and eczema, but not proven to stop scarring alopecia. Alternatives like apremilast and Vtama are also discussed for their anti-inflammatory benefits.

community 6.5 Month Progression 33/Female

in Female 42 upvotes 3 years ago

Maintaining scalp hair and minimizing shedding, treatments used such as Procapil, supplements, topical caffeine, topical estrogen, and scalp massage; suggestions for anagen extenders or pharmaceuticals to help with a short anagen phase.

community Fin and Oral Minoxidil completely changed my hair texture (8months progress)

in Progress Pictures 353 upvotes 1 year ago

Finasteride and oral minoxidil significantly improved hair texture and thickness over 8 months. The user also experienced increased hair growth on the beard and eyebrows.

community (M28) 3 months progress on minoxidil 5%

in Progress Pictures 76 upvotes 2 years ago

A 28-year-old male showed hair regrowth after 3 months using 5% liquid minoxidil twice daily and weekly dermarolling with a 1mm roller. Someone suggested adding finasteride to the treatment.

community can someone help me identify these pls

in Treatment 4 months ago

The user is experiencing diffuse thinning and inflammation despite using 2.5mg dutasteride daily, ciclopirox, and ketoconazole shampoos. They are considering treatments like hydroxychloroquine and JAK inhibitors due to suspected scarring alopecia and have faced challenges in obtaining a scalp biopsy.

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