research Cutaneous thrombosis and ANCA-positive vasculitis associated with propylthiouracil therapy
Propylthiouracil, a thyroid medication, can cause skin blood clots and immune-related blood vessel inflammation.
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5 / 1000+ results research Targeted Overexpression of the Angiogenesis Inhibitor Thrombospondin-1 in the Epidermis of Transgenic Mice Prevents Ultraviolet-B-Induced Angiogenesis and Cutaneous Photo-Damage
This study found that chronic ultraviolet-B exposure increased skin vascularization and wrinkle formation in mice, while overexpressing the angiogenesis inhibitor thrombospondin-1 reduced these effects, suggesting angiogenesis inhibition as a potential approach to prevent photo-damage.
research Generalised cutaneous necrosis: a complication of low-molecular-weight heparin
This case report documents the first known instance of heparin necrosis linked to tinazaparin, indicating that low-molecular-weight heparin may still cause serious side effects like conventional heparin.
research Cutaneous necrosis after injection of polyethylene glycol–modified interferon alfa
In this study, pegylated interferon alfa-2b injections led to local cutaneous reactions, including cutaneous necrosis, in patients with hepatitis C and chronic myelocytic leukemia, requiring dose modifications or treatment withdrawal in some cases.
research Localized cutaneous necrosis associated with the antiphospholipid syndrome
This case report illustrates the risk of skin necrosis in patients with high antiphospholipid antibody levels after stopping anticoagulation therapy, highlighting the necessity for careful monitoring.
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