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GlossaryEpidermis (Cutaneous Epithelium)

outermost skin layer providing protection against environmental factors

The epidermis is the outermost layer of the skin, serving as a protective barrier against environmental factors such as pathogens, UV radiation, and physical injury. It is composed of multiple layers of cells, primarily keratinocytes, which undergo a continuous process of renewal and shedding. This layer also contains melanocytes, which produce melanin, the pigment responsible for skin color.

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Ectopic Expression of the Nude Gene Induces Hyperproliferation and Defects in Differentiation: Implications for the Self-Renewal of Cutaneous Epithelia

research Ectopic Expression of the Nude Gene Induces Hyperproliferation and Defects in Differentiation: Implications for the Self-Renewal of Cutaneous Epithelia

69 citations, August 1999 in “Developmental biology”

The nude gene causes skin cell overgrowth and improper development, leading to hair and urinary issues.

research Isolation and Characterization of Cutaneous Epithelial Stem Cells

4 citations, January 2013 in “Humana Press eBooks”

Scientists found ways to identify and collect skin stem cells, which vary by skin area and are delicate.

research Cutaneous Epithelial Stem Cells

November 2013 in “Elsevier eBooks”

Skin and hair renewal is maintained by both fast and slow cycling stem cells, with hair regrowth primarily driven by specific stem cells in the hair follicle bulge. These cells can also help heal wounds and potentially treat hair loss.

Epithelial Cells in the Hair Follicle Bulge Do Not Contribute to Epidermal Regeneration After Glucocorticoid-Induced Cutaneous Atrophy

research Epithelial Cells in the Hair Follicle Bulge Do Not Contribute to Epidermal Regeneration After Glucocorticoid-Induced Cutaneous Atrophy

23 citations, July 2007 in “The journal of investigative dermatology/Journal of investigative dermatology”

Hair follicle bulge cells don't help skin regrow after glucocorticoid damage; interfollicular epidermis cells do.

research Effects of Periplaneta Americana Extracts on the Growth and Proliferation of Cutaneous Interstitial Cells in Cutaneous-Wound Healing

9 citations, August 2022 in “Frontiers in Pharmacology”

Kangfuxin (KFX) extract speeds up wound healing and improves skin regeneration.

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community How do you use rosemary oil and peppermint oil?

in Question 6 upvotes 4 years ago

Rosemary oil and peppermint oil may promote hair growth and increase cutaneous blood flow, showing promise as treatments for androgenetic alopecia. Minoxidil 2% is also used for treating hair loss.

community Scientific evidence for Peppermint & Rosemary oils + My Experience

in Research/Science 114 upvotes 2 years ago

Natural treatments for hair loss, specifically peppermint oil and rosemary oil; how they can be used as a supplementary or alternative treatment to pharmaceuticals such as finasteride and minoxidil; and the personal experience of the user Divallo, who has seen an increase in density and thickness after using these oils for around 2.5 years. The post also touches on the potential antifungal properties of the oils and their effects on cutaneous blood flow.

community high bloodpressure and crown thinning in early 20s

in Is this regrowth? 9 upvotes 6 months ago

A user with kidney disease and high blood pressure experienced hair thinning, especially around the vertex. They are currently using finasteride and oral minoxidil but are considering whether to resume blood pressure medication despite managing symptoms with diet and exercise.

community HMI-115 update: Chime Biologics and Hope Medicine Enter Manufacturing Agreement to Speed up the Launch of First-in-class Antibody Drug HMI-115 Targeting Endometriosis and Androgenic Alopecia

in Research/Science 112 upvotes 1 year ago

Chime Biologics and Hope Medicine are speeding up the launch of a first-in-class antibody drug, HMI-115, for endometriosis and androgenic alopecia. The treatment involves a series of subcutaneous injections, has shown promising results in phase 1, and continues to promote hair regrowth even after the treatment is stopped.

community Androgenetic alopecia is a skin disease: DHT-mediated skin disorders

in Research/Science 65 upvotes 1 year ago

Dihydrotestosterone (DHT) impacts various skin conditions, including Androgenetic alopecia and seborrheic dermatitis, by causing overactivity in sebaceous glands. Topical medications Tacrolimus and Clobetasol can reduce these inflammatory conditions, and treatments like RU58841, Minoxidil, and Finasteride may also be beneficial.

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