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research Crystal Structure of 3-Oxo-4-Aza-5-Alpha-Androstone-17 β-Tert-Butyl Carboxamide with an O···H–(C, N) Acceptor Four-Center Hydrogen Bond

2 citations, December 2008 in “Journal of Chemical Crystallography”

The research shows that hydrogen bonds greatly affect the crystal structure of a Finasteride derivative.

research Molecular Docking Studies and ADME Prediction of Novel Isatin Analogs with Potent Anti-EGFR Activity

15 citations, January 2014 in “Medicinal chemistry”

Some new isatin compounds could be strong cancer-fighting drugs because they fit well in cancer-related proteins and have good drug-like properties.

Crystallization and Preliminary X-Ray Analysis of the Human Androgen Receptor Ligand-Binding Domain with a Coactivator-Like Peptide and Selective Androgen Receptor Modulators

research Crystallization and Preliminary X-Ray Analysis of the Human Androgen Receptor Ligand-Binding Domain with a Coactivator-Like Peptide and Selective Androgen Receptor Modulators

1 citations, November 2008 in “Acta crystallographica”

Scientists successfully created and analyzed the structure of a part of the human androgen receptor with specific modulators and a peptide to understand how it binds differently in various tissues.

Bioavailability Assessment of Topical Delivery Systems: Effect of Vehicle Evaporation Upon In Vitro Delivery of Minoxidil from Solution Formulations

research Bioavailability Assessment of Topical Delivery Systems: Effect of Vehicle Evaporation Upon In Vitro Delivery of Minoxidil from Solution Formulations

44 citations, October 1989 in “International Journal of Pharmaceutics”

Minoxidil's effectiveness decreases as vehicle evaporates; concentration and thermodynamic activity matter.

research Roles of Steroid Sulfatase in Brain and Other Tissues

22 citations, January 2008 in “Physiological Research”

Steroid sulfatase is important for activating hormones that affect memory, brain function, and certain diseases, and could be a target for treating hormone-related disorders.

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Community Join

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community questions for the pyrilutamide users here

in Treatment 7 upvotes 2 years ago

The conversation discusses the storage and use of pyrilutamide for hair loss, where one user advises against keeping it in the freezer as it may crystallize the active compounds.

community sebum overproduction on fin 1mg and hair thinning

in Finasteride/Dutasteride 3 upvotes 7 months ago

User is experiencing hair thinning and sebum overproduction after starting finasteride and a hair growth supplement containing biotin, iron, zinc, and calcium. They suspect the finasteride might be fake but have noticed a side effect of watery semen.

community HMI 115 Phase 2 - Leaked pics from Discord

in Research/Science 366 upvotes 7 months ago

The conversation discusses HMI 115, a new hair loss treatment with promising results, showing a significant increase in hair density after two months. Some users are skeptical, while others are hopeful for its release and potential affordability.

community Minoxidil BAILLEUL 5% Men - Systematic Crystallisation In Sprayers and Bottles

in Minoxidil 2 upvotes 10 months ago

The post discusses issues with Minoxidil BAILLEUL 5% Men, specifically sprayer clogging and crystallization in bottles. Recommendations include rinsing the sprayer and soaking the bottle in hot water to dissolve crystals, with calculations suggesting the product remains effective despite these issues.

community Never had better results than a few drops of minoxidil under the tongue. I've tried various combinations.

in Minoxidil 12 upvotes 2 years ago

The user reports the best results for hairline regrowth using 3 drops of minoxidil under the tongue once daily, after trying various treatments including loniten, topical minoxidil with estrogen, dutasteride, and finasteride. Additional regimen includes occasional tretinoin, collagen peptides, crude oil massages, violet ray device, nizoral, and Listerine for scalp health.

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