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Glossary Cronkhite-Canada Syndrome

rare disorder causing gastrointestinal polyps, alopecia, and nail changes

Cronkhite-Canada Syndrome (CCS) is a rare, non-inherited disorder characterized by gastrointestinal polyps, diarrhea, weight loss, and distinctive changes in the skin, hair, and nails, including alopecia (hair loss). The exact cause is unknown, but it is believed to involve an abnormal immune response.

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Gastrointestinal Polyposis with Protein-Losing Enteropathy, Abnormal Skin Pigmentation, and Loss of Hair and Nails (Cronkhite-Canada Syndrome)

research Gastrointestinal polyposis with protein-losing enteropathy, abnormal skin pigmentation and loss of hair and nails (Cronkhite-Canada syndrome)

26 citations , September 1969 in “The American journal of medicine”

This article reviews Cronkhite-Canada syndrome as a distinct condition from Peutz-Jeghers syndrome and familial polyposis, with cases showing gastrointestinal polyposis, skin, hair, nail abnormalities, and hypoproteinemia.

Cronkhite-Canada Syndrome Associated with Serrated Adenoma and Malignant Polyp: A Case Report and Literature Review of 13 Cases in Korea

research Cronkhite-Canada Syndrome Associated with Serrated Adenoma and Malignant Polyp: A Case Report and a Literature Review of 13 Cronkhite-Canada Syndrome Cases in Korea

21 citations , January 2013 in “Clinical Endoscopy”

This study reports the first case in South Korea of Cronkhite-Canada syndrome associated with malignant colon polyp and serrated adenoma.

Cronkhite-Canada Syndrome: Report of an Unusual Case

research Cronkhite-Canada syndrome: Report of an unusual case

21 citations , October 1980 in “Gastroenterology”

This report is the first to associate Cronkhite-Canada syndrome with multiple myeloma, describing regenerative pseudopolyps in a 58-year-old woman rather than true adenomatous polyps.

Spontaneous Improvement of Cronkhite-Canada Syndrome in a Postpartum Female

research Spontaneous improvement of Cronkhite-Canada syndrome in a postpartum female

19 citations , May 1984 in “Digestive diseases and sciences”

A young woman's Cronkhite-Canada syndrome improved on its own after she gave birth.

Cronkhite–Canada Syndrome: From Clinical Features to Treatment

research Cronkhite–Canada syndrome: from clinical features to treatment

19 citations , August 2020 in “Gastroenterology report”

This review discusses the characteristics and challenges in treating Cronkhite–Canada syndrome but reports no new clinical findings, emphasizing the need for better understanding and uniform treatment approaches.

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