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GlossaryCronkhite-Canada Syndrome

rare disorder causing gastrointestinal polyps, alopecia, and nail changes

Cronkhite-Canada Syndrome (CCS) is a rare, non-inherited disorder characterized by gastrointestinal polyps, diarrhea, weight loss, and distinctive changes in the skin, hair, and nails, including alopecia (hair loss). The exact cause is unknown, but it is believed to involve an abnormal immune response.

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research Clinical Features of Taste Disorders in Cronkhite-Canada Syndrome: A Report of 10 Cases

December 2024 in “Chemical Senses”

Taste disorders in Cronkhite-Canada syndrome are severe in the front of the tongue but improve with treatment.

research Alopecia in Cronkhite-Canada Syndrome: Is It Truly Telogen Effluvium?

3 citations , May 2019 in “Australasian Journal of Dermatology”

Hair loss in Cronkhite-Canada syndrome may be caused by autoimmune factors, not just stress or malabsorption.

research Cronkhite-Canada Syndrome Diagnosis in the Absence of Gastrointestinal Polyps

5 citations , March 2013 in “International journal of surgical pathology”

Cronkhite-Canada syndrome can be diagnosed without gastrointestinal polyps if there is severe mucosal atrophy and edema.

research Cronkhite-Canada Syndrome (CCS)—A Rare Case Report

17 citations , January 2015 in “JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH”

Cronkhite-Canada syndrome is a rare, non-inherited condition causing various symptoms like polyps, hair loss, and weight loss.

research An Unusual Case of Diarrhea, Dysgeusia, and Grainy and Nodular Mucosa

August 2023 in “Gastroenterology”

A 78-year-old man with Cronkhite-Canada syndrome improved significantly after treatment and remains symptom-free.

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