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GlossaryPrecocious Puberty (CPP)

early onset of puberty before age 8 in girls

Precocious puberty, also known as early puberty, is a condition where a child's body begins to develop into that of an adult (puberty) at an unusually early age, typically before age 8 in girls and before age 9 in boys. This early onset of puberty can lead to rapid growth, development of secondary sexual characteristics, and potential psychological and social challenges. It may be caused by various factors, including hormonal imbalances, genetic conditions, or underlying medical issues.

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research Investigation of Follicular and Non-Follicular Pathways for Polyarginine and Oleic Acid-Modified Nanoparticles

47 citations, November 2012 in “Pharmaceutical research”

Surface-modified nanoparticles mainly use non-follicular pathways to enhance skin permeation of ibuprofen and could improve treatment for inflammatory skin diseases.

research Case 5: A Very Tall 7-Year-Old Boy with Medulloblastoma

1 citations, January 2018 in “Pediatrics in review”

A 7-year-old boy with a brain tumor developed early puberty, which was successfully treated with medication.

The Effect of Gonadotropin-Releasing Hormone Analog Treatment in Precocious Puberty on Polycystic Ovarian Syndrome Prevalence in Adulthood

research The Effect of Gonadotropin-Releasing Hormone Analog Treatment in Precocious Puberty on Polycystic Ovarian Syndrome Prevalence in Adulthood

January 2024 in “Frontiers in endocrinology”

Treating early puberty with hormone therapy may increase the risk of polycystic ovary syndrome in adults.

Canonical and Dominant Negative Peroxisome Proliferator-Activated Receptor Gamma Isoforms Are Differentially Expressed in Human Skin and Skin Appendages

research Canonical and Dominant Negative Peroxisome Proliferator-Activated Receptor Gamma Isoforms Are Differentially Expressed in Human Skin and Skin Appendages

November 2022 in “The journal of investigative dermatology/Journal of investigative dermatology”

Different types of PPARγ are found in varying amounts in human skin and its parts, which could affect how skin treatments work.

A Randomized Placebo-Controlled Multicenter Study to Evaluate the Safety and Efficacy of Finasteride for Male Chronic Pelvic Pain Syndrome (Category IIIA Chronic Nonbacterial Prostatitis)

research A Randomized Placebo-Controlled Multicenter Study to Evaluate the Safety and Efficacy of Finasteride for Male Chronic Pelvic Pain Syndrome (Category IIIA Chronic Nonbacterial Prostatitis)

127 citations, May 2004 in “PubMed”

Finasteride may help some male chronic pelvic pain patients, but more research needed.

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community 2 years finasteride about 6 months of dutasteride

in Progress Pictures 109 upvotes 2 weeks ago

The user switched from finasteride to dutasteride due to a prostate condition and noticed mixed results, with some improvement in the middle hairline but worsening at the temples, while also using minoxidil. Other users shared similar experiences with shedding and emphasized the need for patience, as dutasteride can take several months to show full effects.

community Does finasteride decrease free testosterone?

in Research/Science 186 upvotes 4 months ago

Finasteride may decrease free testosterone by increasing SHBG, potentially causing side effects like reduced libido and hormonal changes. Some find it effective for hair loss, while others experience negative effects.

community 33M, Fin only, If I can then so can you! 4 years of progress on my hairline.

in Finasteride/Dutasteride 2 years ago

A user's 4-year journey of using Finasteride to improve their hairline, which they started noticing results from within the first month, and experienced significant shedding during the first year. They also tried Minoxidil but had heart palpitations so stopped taking it.

community My mum is mad annoying about Fin.

in Chat 245 upvotes 1 year ago

A 25-year-old man discusses his struggles with his mother's opposition to his use of Finasteride for hair loss treatment, despite it improving his condition and self-control after a hair transplant. He expresses frustration over her blaming the medication for various issues and the stress caused by her insistence to stop taking it.