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This study found that murine vibrissa hair follicle stem cells can be differentiated into corneal epithelial-like cells in vitro using limbus-specific microenvironmental factors, suggesting a potential therapeutic source for ocular surface disorders.

This study demonstrates that bulge KSCs from hair follicles can transdifferentiate into corneal epithelial-like cells under specific conditions, which could support bioengineered cornea development.

This study found that murine vibrissa hair follicle stem cells can differentiate into corneal epithelial-like cells in vitro when cultured with limbus-specific microenvironmental factors.

This study found that dedifferentiated corneal epithelial cells can revert to a stem-cell-like state, aiding tissue homeostasis and repair, with this plasticity limited to the epithelial lineage and enhanced by niche-derived cytokines.

This review summarizes recent insights into corneal limbal stem cell differentiation and the potential role of progenitor-like cells, but reports no new experimental results.