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research Genomewide analysis of copy number variants in alopecia areata in a Central European cohort reveals association with MCHR2

29 citations , June 2016 in “Experimental Dermatology”

This study provides suggestive evidence that duplications in the MCHR2 gene may be involved in the pathogenesis of alopecia areata.

Integrative Analysis of Rare Copy Number Variants and Gene Expression Data in Alopecia Areata Implicates an Etiological Role for Autophagy

research Integrative analysis of rare copy number variants and gene expression data in alopecia areata implicates an aetiological role for autophagy

20 citations , June 2019 in “Experimental Dermatology”

This study identified 14 genes affected by copy number variants that may contribute to alopecia areata, including four genes notably involved in autophagy and chromatin remodeling.

research De novo single-nucleotide and copy number variation in discordant monozygotic twins reveals disease-related genes

36 citations , March 2019 in “European Journal of Human Genetics”

This study found genetic variations, including de novo variants and copy number variations, that may be associated with phenotypic discordance in monozygotic twins with various clinical conditions.

research Genomic Analysis of Trichotillomania

1 citations , January 2025 in “medRxiv”

In this case-control study, researchers did not find genome-wide significant genetic variants for trichotillomania, but cases had higher polygenic risk for psychiatric disorders and certain neuropsychiatric-associated copy number variants.

research Compilation of a comprehensive gene panel for systematic assessment of genes that govern an individual’s drug responses

13 citations , October 2010 in “Pharmacogenomics”

This study constructed a panel of pharmacokinetic and pharmacodynamic genes, revealing that current SNP chips insufficiently capture many drug-response gene variants, highlighting the need for complementary genetic approaches.

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community Does it work? Maneup GHK-Cu hair growth serum

10 upvotes 2 years ago

The conversation is about the effectiveness of Maneup GHK-Cu hair growth serum, a topical treatment for hair loss. The user is considering trying it but is skeptical due to issues others have had with DIY injections of a similar substance.

community So we have 20k dollars human like machines available but no new effective treatment for hairloss since finasteride :)

in Chat 237 upvotes 1 year ago

There have been no new effective hair loss treatments since finasteride, despite technological advancements. Current treatments include finasteride, minoxidil, and RU58841, with ongoing challenges and potential future solutions in research.

community I am actually regrowing my hairline without minoxidil or finasteride (mechanical stimulation)

129 upvotes 8 years ago

Regrowing hairline without the use of Minoxidil or Finasteride, and instead using mechanical stimulation such as Derma Roller, Nizoral, Zinc Pyrithione, Scalp Massage, Scalp Exercise, Fish Oil and other topical solutions. It is cautioned that there are risks associated with not using medically-prescribed treatments, but it is suggested to consider mechanical stimulation in addition to those prescribed treatments.

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