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research Rejuvenating Senescent Hair Follicles: A Novel Conjugated Linoleic Acid Based Nanovesicle Approach to Treat Androgenic Alopecia

November 2025 in “Journal of Nanobiotechnology”

A new treatment using special nanovesicles with linoleic acid shows promise in improving hair growth and reducing irritation for hair loss.

research Activation of Hair Cell Growth Factors by Linoleic Acid in Malva Verticillata Seed

17 citations , April 2021 in “Molecules/Molecules online/Molecules annual”

Linoleic acid from Malva verticillata seeds may help treat hair loss by promoting hair cell growth and blocking baldness signals.

research Oleic Acid Nanovesicles of Minoxidil for Enhanced Follicular Delivery

27 citations , September 2018 in “Medicines”

Oleic acid nanovesicles improve minoxidil absorption in hair follicles for alopecia treatment.

research Combination Therapy Profoundly Improved Skin Flap Survival by Modulating KATP Channels and Nitric Oxide

1 citations , January 2019 in “Advances in Medical Sciences”

The combination of azelaic acid, minoxidil, and caffeine significantly increased the survival of skin flaps by affecting certain body channels and nitric oxide levels.

research Vitamin D Receptor: Molecular Signaling and Actions of Nutritional Ligands in Disease Prevention

271 citations , September 2008 in “Nutrition reviews”

Vitamin D receptor interacts with certain dietary components to help prevent diseases and regulate hair growth.

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community 5 alpha reductase type 1 is in brain tissue producing the main endogenous gabaergic allopregnanolone, not 2. How can finasteride as a 5ar2 lower that?

in Finasteride/Dutasteride 27 upvotes 1 year ago

Finasteride and dutasteride are discussed for hair loss, with concerns about their effects on neurosteroids and potential side effects like depression. Alternatives like topical estrogen and lifestyle changes are considered, with varying opinions on mental health and hair regrowth.

community Daily aspirin is ruining your Min. gains

in Minoxidil 6 upvotes 2 years ago

Aspirin reduces the effectiveness of minoxidil for hair loss. Quercetin and 5-ASA medications also inhibit the necessary enzyme for minoxidil to work.

community Study: There is 70x Higher Unconjugated DHT in Feces Compared To Blood Levels in Young Adults - Gut Microbiota Manages DHT Recycling and Metabolism

in Research/Science 194 upvotes 5 months ago

Gut microbiota significantly influences androgen metabolism, impacting hair loss treatments like finasteride. Probiotics, dietary changes, and fecal microbiota transplants may help manage DHT levels and improve hair health.

community Testosterone and hair loss seeming irrelevance

in Research/Science 83 upvotes 2 years ago

The conversation is about the role of testosterone in hair loss and the effectiveness of different treatments. The conclusion is that DHT is the main culprit for hair loss, and finasteride has been proven to work long-term in maintaining and regrowing hair. Testosterone may have a minor effect, but it is not the primary cause of hair loss.

community 4+ Years on Dut: Update and AMA

in Update 113 upvotes 2 years ago

Hair loss treatments, such as Dutasteride, Minoxidil, and Finasteride. Advice is given to give the medications time to work and to consider a Hair Transplant in order to fill any gaps caused by continuing hair loss.

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