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a JAK inhibitor for alopecia areata and other autoimmune conditions
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5 / 39 resultslearn RU58841
a potent but unapproved and potentially problematic topical anti-androgen
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powerful topical and oral anti-androgen used mostly by women
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learn Finasteride
Frontline, gold standard treatment for combatting androgenic alopecia
Research
5 / 1000+ results
research Severe Cardiac Conduction Abnormalities Associated with Atypical Toxic Shock Syndrome
A boy with toxic shock syndrome had severe heart rhythm problems but recovered with treatment.
research Reduced Plakoglobin Increases the Risk of Sodium Current Defects and Atrial Conduction Abnormalities in Response to Androgenic Anabolic Steroid Abuse
This study investigates the impact of androgenic anabolic steroids (AAS) on atrial conduction abnormalities, particularly in the context of arrhythmogenic right ventricular cardiomyopathy (ARVC), which is linked to desmosomal gene defects like reduced plakoglobin expression. Analyzing clinical records from 146 ARVC patients, the study found a higher prevalence of ARVC in males, who also exhibited increased atrial arrhythmias and P wave changes. In an experimental setup, young male mice with reduced plakoglobin expression showed exacerbated atrial electrical remodeling when exposed to 5α-dihydrotestosterone (DHT), including P wave abnormalities, slowed atrial conduction, and sodium current depletion. The findings suggest that AAS use, combined with plakoglobin deficiency, heightens the risk of atrial arrhythmias, particularly in males with desmosomal gene variants.
research Correlation Between the 24-Hour Urine Aldosterone Levels and Atrial Electromechanical Conduction Time
Men with male pattern baldness have increased arterial stiffness.
research Heat Transfer in Human Hair
Heat transfer in hair is slower in groups of hair, increasing the risk of damage from high-temperature styling tools.
research Macrophages Regulate Schwann Cell Maturation After Nerve Injury
Macrophages help heal nerves by aiding the maturation of Schwann cells and are important for nerve repair.
Community Join
5 / 1000+ resultscommunity Minoxidil hairs not growing to full length
New hair growth from minoxidil and finasteride is not reaching full length, possibly due to slow growth cycles. Users discuss dosing strategies for oral minoxidil to improve efficacy and minimize side effects, with advice against consuming topical minoxidil orally.
community New and Interesting HairLoss Studies/Papers/Reviews
Hair loss treatments discussed include Dutasteride with Ketoconazole, tissue engineering strategies, and androgenetic alopecia therapies. Massage doubles follicular retention, improving treatment effectiveness.
community I'm conducting the biggest study on Creatine Monohydrate's effects on Hair Health
Creatine monohydrate's potential link to hair loss, with mixed opinions on its effects. Treatments like minoxidil, finasteride, and RU58841 are discussed.
community Kintor is conducting a phase III trial of Pyrilutamide in combination with Minoxidil 💀
Kintor is testing Pyrilutamide with Minoxidil for hair loss. Users are skeptical about its effectiveness and concerned about limited treatment options if this fails.
community Update about Hair Follicle Glucose Metabolism: New Clinical Data Collection with Ex-President Of American Board Of Hair Restoration Surgery.
David Barreto shared that a London-based research group is conducting a 12-month trial for a new nutraceutical treatment for pattern hair loss, designed with Dr. Carlos Puig. The trial aims to provide robust data, with results expected in 1-2 years, potentially representing a significant advancement since finasteride’s introduction in 1997.