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12-Methoxy Carnosic Acid Efficacy Determination and Optimization Through Computational Tools for 5-Alpha Reductase Enzyme and Using Finasteride as Reference Molecule

research 12-Methoxy Carnosic Acid Efficacy Determination and Optimization Through Computational Tools for 5-Alpha Reductase Enzyme and Using Finasteride as Reference Molecule

December 2023 in “Research Square (Research Square)”

12-Methoxy carnosic acid from rosemary might be a good natural treatment for hair loss.

research Computational Drug Discovery in Chemotherapy-Induced Alopecia via Text Mining and Biomedical Databases

3 citations, April 2019 in “Clinical Therapeutics”

Computational tools identified 29 drugs that could potentially target 19 genes involved in chemotherapy-induced hair loss, which could lead to more effective treatments.

research Regenerative Medicine Meets Mathematical Modelling: Developing Symbiotic Relationships

25 citations, April 2021 in “npj Regenerative Medicine”

Mathematical modeling can improve regenerative medicine by predicting biological processes and optimizing therapy development.

research Homology Modeling of 5-Alpha-Reductase 2 Using Available Experimental Data

5 citations, January 2018 in “Interdisciplinary sciences: computational life sciences”

Accurate protein modeling can help develop new treatments for prostate cancer and other diseases.

research Role of Beta-Catenin Activation Levels and Fluctuations in Controlling Cell Fate

28 citations, February 2019 in “Genes”

Proper control of β-catenin activity is crucial for development and preventing diseases like cancer.

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Community Join

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community Fats on your Head to Stop Hair Loss?

in Research/Science 138 upvotes 9 months ago

The conversation discusses the potential of long-chain unsaturated fatty acids, like oleic and linoleic acid, as an additional treatment for hair loss, which may inhibit the enzyme responsible for converting testosterone to DHT and promote hair growth. Users humorously suggest using oils topically and discuss other hair loss treatments, but the main focus is on the science behind fatty acids and their role in hair health.

community So we have 20k dollars human like machines available but no new effective treatment for hairloss since finasteride :)

in Chat 237 upvotes 1 month ago

There have been no new effective hair loss treatments since finasteride, despite technological advancements. Current treatments include finasteride, minoxidil, and RU58841, with ongoing challenges and potential future solutions in research.