1 citations
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January 2018 in “Skin appendage disorders” The complement system might be involved in the development of alopecia areata and could lead to new treatments.
May 2020 in “The journal of investigative dermatology/Journal of investigative dermatology” BIVV009 is a safe treatment for bullous pemphigoid that reduces C3 deposition without harmful side effects.
60 citations
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February 1992 in “British Journal of Dermatology” This study investigated whether serum from patients with alopecia areata (AA) and alopecia universalis (AU) affected hair growth in human scalp skin grafts on nude mice. Forty mice were used, with some receiving patients' serum and others normal serum, alongside topical treatments of cyclosporin or olive oil. Hair growth occurred in most grafts, and the serum from AA and AU patients did not inhibit this process. Although immunofluorescence showed immunoglobulin and complement deposition in hair follicles, particularly in affected skin, the injection of patient serum did not alter hair growth, indicating that the serum did not play a role in inhibiting hair growth in this model.
33 citations
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August 2006 in “Journal der Deutschen Dermatologischen Gesellschaft” Pregnancy can cause specific skin conditions that need correct diagnosis and treatment to protect both mother and baby.
3 citations
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July 2017 in “Elsevier eBooks” Skin reactions are a common reason for emergency visits due to drug allergies, with some severe cases needing intensive care.