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      community Any good experiences with Alfatradiol ?

       4 upvotes 6 years ago
      Alfatradiol is discussed as a weak 5ARI and estrogen, not as effective as minoxidil, RU58841, or CB-03-01, but a safe alternative for those who can't use finasteride. Users express frustration over the lack of strong FDA-approved topical antiandrogens for hair loss.

      community Anyone tried CB-03-01?does it work ?

      in Research/Science  2 upvotes 1 year ago
      CB-03-01, also known as Breezula, is being considered as an alternative to DHT blockers for hair loss. Users are discussing its effectiveness, potential regrowth, side effects like scalp irritation, and hormonal impacts.

      community Finasteride's impact on blood pressure - mechanism of action

       4 upvotes 5 years ago
      Finasteride may cause mild blood pressure-related side effects in less than 10% of users, unlike minoxidil, which has stronger effects. Alternatives like topical ketoconazole and dermarollers are suggested for those concerned about finasteride's side effects.

      community i'm Considering adding hair stimulant: stemoxydine or alphatradiol

       5 upvotes 1 year ago
      The user is considering adding Stemoxydine to their hair loss regimen, as they already use topical finasteride with rosemary and cannot use Minoxidil. They are seeking feedback on Stemoxydine and Alphatradiol, and another user mentions 2-deoxy-d-ribose as a potential option.

      community Oral dut 0.5mg and oral minoxidil 5mg

       4 upvotes 5 months ago
      The user is using oral dutasteride, oral minoxidil, topical minoxidil, finasteride solution, tazarotene, calcipotriol, and a peptide serum for hair loss but is concerned about continued hair shedding. They are advised to stop smoking as it may worsen hair loss and to give the treatments more time to work.

      community any females on RU58841/minoxidil 2.5%?

       6 upvotes 5 years ago
      A female user is considering using RU58841 with minoxidil 2.5% to reduce side effects like facial hair from minoxidil 5%, while also using copper peptides and a hair serum. Other users discuss alternative treatments like spironolactone, alfatradiol, and the side effects of finasteride.

      community Better Than Minoxidil? Topical Sodium Valproate

       50 upvotes 1 year ago
      Topical sodium valproate may promote hair growth by inhibiting GSK3β, allowing beta-catenin to proliferate, but it has potential side effects and requires more research. The conversation also mentions skepticism about a product called Vdphlo1, which includes sodium valproate and other ingredients.

      community Finasteride induced acne!? ANY suggestions pls! Zinc?

       11 upvotes 3 years ago
      Finasteride may cause acne for some users, possibly due to increased testosterone or estrogen levels. Zinc, gluconic acid, and B5 cream are suggested treatments for managing this acne.

      community Thoughts on Avixis Alfatradiol?

       4 upvotes 4 years ago
      Avixis Alfatradiol is a topical 5-alpha reductase inhibitor available in Latin America and Germany, but its effectiveness is questioned. A user reported worsened hair loss after using it and recommended finasteride instead due to its proven effectiveness and lower cost.

      community Ketoconazole vs Ciclopirox which one was better for you ?

       3 upvotes 1 year ago
      Switching from ketoconazole to a ciclopirox and zinc pyrithione shampoo significantly reduced hair fall. The user is considering whether to continue using ketoconazole occasionally or combine both shampoos weekly.

      community Zohran Mamdani is on oral minoxidil

       1027 upvotes 3 months ago
      Zohran Mamdani is using oral minoxidil for hair loss. There is discussion about the importance of using a DHT blocker like finasteride alongside minoxidil.

      community MinoxidilMax Latanoprost .01%. Has anybody found this helpful?

       1 upvotes 2 years ago
      The conversation is about the effectiveness of a hair loss treatment product containing 0.01% Latanoprost, with the user considering trying it as a vehicle for RU58841. The user questions whether the dosage is too low to be effective.

      community Losing hairs on aggressive treatment.

      in Transgender  2 upvotes 3 months ago
      The user is experiencing hair loss despite using estradiol, bicalutamide, dutasteride, and topical minoxidil. They stopped minoxidil temporarily, which worsened their condition, and are considering oral minoxidil but are concerned about side effects and cost.

      community What new hair-loss treatments actually look exciting right now (Oct 2025)

       171 upvotes 11 months ago
      New hair loss treatments include Breezula, PP405, ET-02, KX-826, GT20029, VDPHL01, and CosmeRNA, with some showing promise in reactivating stem cells and reversing greying. Breezula and VDPHL01 are highlighted as potential add-ons or alternatives to current treatments like finasteride and minoxidil.

      community My kotoconazole shampoo contain this

      6 months ago
      The conversation discusses the safety and use of ketoconazole shampoo for hair loss, with mentions of zinc pyrithione and selenium sulfide. Users debate the safety of these ingredients, particularly zinc pyrithione, and share opinions on regulatory differences between Europe and the US.

      community Does anyone take bicalutamide for fphl? If so which dose

       4 upvotes 4 years ago
      The conversation is about a female seeking advice on using bicalutamide for female pattern hair loss (FPHL) and considering switching from pumpkin seed oil pills to a stronger treatment. She is looking for dosage information to discuss with her dermatologist.

      community Alfatradiol 1% study rebuttal.

       4 upvotes 3 years ago
      Alfatradiol is often discussed at a 1% concentration, but studies typically use 0.025%. Some users report success using it as a topical treatment alongside other hair loss treatments like finasteride.

      community Farmacia Tristaina’s alfatradiol scam?

       4 upvotes 2 months ago
      The user experienced better results with Ell-Cranell (0.025% alfatradiol) compared to Farmacia Tristaina’s 0.2% alfatradiol solution, which seemed less effective in reducing hair loss. They questioned the efficacy of the compounded solution due to continued shedding and lack of side effects.

      community Vitamins Deficiency and blood works result

      in Treatment  2 upvotes 1 year ago
      The conversation is about a user planning to start minoxidil treatment and considering increasing zinc intake to improve testosterone and libido. They are concerned about potential hair loss due to increased testosterone and are advised to consider magnesium supplementation and the effects of DHT if not on finasteride or dutasteride.

      community Hydrophobic Finasteride. Why don’t we have it?

       6 upvotes 1 year ago
      The conversation discusses the potential benefits of creating a hydrophobic version of finasteride to reduce systemic side effects while maintaining scalp health. It compares this idea to fluridil, which is designed to be hydrophobic and has less systemic absorption.