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Elevated bile acids can inhibit the enzyme AKR1C2, leading to increased DHT levels, which may accelerate hair loss in those predisposed to androgenetic alopecia. Treatments mentioned include topical minoxidil and finasteride.

Finasteride may seem less effective over time due to increased DHT sensitivity or aging, but it still suppresses DHT. Switching to dutasteride offers stronger DHT suppression but may increase estrogen levels.

Caffeine intake may increase DHT levels, but its impact on hair loss is minimal compared to genetic factors. Excessive caffeine can cause health issues, and its effects on hair loss are not directly applicable to humans based on rat studies.

A 27-year-old male reported significant hair improvement after 6 months on 0.5 mg Dutasteride daily and 2.5 mg Minoxidil daily, with Nizoral shampoo twice a week. He experienced increased body/facial hair but no other side effects, and his hair density and hairline improved.

The user is trying to maximize minoxidil's effectiveness by applying it for only one hour to avoid spreading it to furniture and pets, especially cats. They experience side effects when combining minoxidil with dermarolling and are considering alternatives like oral minoxidil or microneedling.

Onion juice helped with hair loss but was smelly and inconvenient. The user now uses dutasteride and minoxidil, finding them more effective and practical.

User shared progress on hair regrowth using Fin 1 mg/day for 4 years, Min 2x/day for 3 years, Estradiol 4mg/day, and Spironolactone 100mg/day for 3.5 months. They noted significant hairline recovery and advised against HRT for cis men due to feminizing effects.

The conversation discusses the possibility of transplanting leg and arm hair to the scalp for hair loss treatment. Minoxidil is mentioned as a potential aid for hair growth, but concerns about the effectiveness and appearance of body hair on the head are raised.

The conversation is about overcoming fear of finasteride/dutasteride for hair loss treatment. Users suggest starting with a small supply, noting side effects are rare and reversible, and emphasize personal comfort and confidence.

Finasteride increased libido for some users, with effects normalizing after a few weeks to months. Other treatments mentioned include Dutasteride and Minoxidil.

Users discuss their experiences with finasteride, expressing regret over delayed use due to misinformation and sharing mixed outcomes, including side effects and benefits. Treatments mentioned include finasteride, dutasteride, and minoxidil.

Topical finasteride results in plasma levels 100 times lower than oral finasteride, potentially reducing systemic side effects. Users report similar efficacy with fewer side effects, suggesting a preference for topical application.

Finasteride can impact neurosteroids, potentially causing depression and other side effects in some users. Despite these concerns, many continue using it for hair loss, with some switching to topical applications to mitigate side effects.

A user has been taking finasteride for 7.5 months and experiencing shedding since the second month, leading to significant hair thinning. Other users suggest continuing the treatment, as shedding is normal, and some have seen improvements after 8 months.

The conversation discusses future hair loss treatments, with mentions of dutasteride potentially gaining FDA approval and increased popularity. Skepticism remains about significant advancements due to limited funding and reliance on cosmetic companies.

The conversation humorously speculates on whether an elderly man's good hairline is due to finasteride, dutasteride, or genetics. It also discusses the role of DHT and genetics in hair loss.

Finasteride and minoxidil significantly improved the user's hair and acne, boosting their confidence and helping them regain self-esteem. Dermarolling also contributed to hair regrowth, and the user continues to see improvements at 27 years old.

The conversation expresses frustration over the lack of clear evidence regarding the effectiveness and systemic impact of topical Dutasteride for hair loss treatment, despite years of discussion. People are criticized for not conducting proper research and for providing contradictory anecdotal claims.

A 25-year-old man discusses his struggles with his mother's opposition to his use of Finasteride for hair loss treatment, despite it improving his condition and self-control after a hair transplant. He expresses frustration over her blaming the medication for various issues and the stress caused by her insistence to stop taking it.

The conversation discusses various celebrities who reportedly use hair loss treatments like finasteride and dutasteride. Users share their experiences and opinions on starting treatment, with some encouraging the original poster to consult a dermatologist and consider treatment before it's too late.

A user shared their 2-month hair growth progress using only Minoxidil, noting significant improvement and plans to continue despite a genetic predisposition to baldness. They apply Minoxidil twice daily, experienced a heat rash, and chose not to use Finasteride due to side effects.

The conversation discusses personal experiences with hair loss treatments, specifically Minoxidil and Finasteride, with some users regretting not starting treatment earlier and others experiencing side effects. Some users are considering or have switched to topical formulations due to side effects from oral medications.

The user has been using finasteride for almost a year, starting at age 18, and added tretinoin and 5% topical minoxidil 1-2 months ago. They are concerned about hair receding again despite the treatments.

A 25-year-old has been using finasteride for four years to treat hair loss, starting at age 21, and has experienced significant hair thickening without side effects. Others in the conversation share varied results and experiences with finasteride, with some considering adding minoxidil to their treatment.

TDM-105795 showed promising hair growth results, with higher efficacy than placebo and minimal side effects. It activates dormant hair follicle stem cells and may maintain gains without immediate loss, unlike minoxidil.

The conversation is about Jordan Peterson allegedly getting a hair transplant, with various users mocking his way of speaking and debating the ethics of him potentially hiding the procedure. Some users discuss the natural look of the transplant and the implications of getting one at an older age.

The conversation compares Finasteride and Dutasteride for hair loss treatment, discussing their effectiveness and side effects. Users share personal results and consider combining treatments like Dutasteride with RU58841.

An 18-year-old male used anti-androgens and oral Minoxidil for 10 months to treat hair loss. He initially used 1mg Finasteride and 5% topical Minoxidil for 5 months, then switched to Dutasteride for 4.5 months and inconsistently used 5mg oral Minoxidil for 2 months due to availability issues.

A user has been using minoxidil for hair loss and has seen positive results, but is seeking additional treatments to enhance its effects. One suggestion given is to use finasteride alongside minoxidil.

A user shared their frustration about their cousin's refusal to take their advice on using finasteride for aggressive hair loss, despite the cousin's desperation and current use of minoxidil and consideration of PRP injections. The user, who has done extensive research, suggested the cousin needs a 5ar inhibitor, but the cousin dismisses the advice because the user isn't a doctor.