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      community CAUTION: My Experience with RU58841

      in Treatment  13 upvotes 1 year ago
      The user experienced concerning side effects like throat irritation, shortness of breath, chest pain, and testicle pain after using RU58841 for hair loss, despite also using finasteride and minoxidil. Other users shared mixed experiences, with one advising to stop using RU58841 due to similar side effects, while another reported significant hair loss reduction without side effects.

      community Quit vaping/smoking = 80% less loss

      in Research/Science  235 upvotes 8 months ago
      Quitting vaping significantly reduced hair loss for a user who was a heavy vaper and also taking finasteride. Some participants suggest nicotine's vasoconstrictive properties may worsen hair loss, while others share personal anecdotes of hair improvement after quitting smoking or vaping.

      community DHT and 5AR respect post, it's importance within the brain

      in Research/Science  111 upvotes 9 months ago
      The conversation discusses whether to use finasteride for hair loss, considering its role in inhibiting DHT and 5AR, which can affect brain function and mood. Some users report anxiety and depression from finasteride, while others do not experience these side effects and emphasize the importance of DHT for brain and prostate health.

      community My nuclear protocol (scary but very effective)

      in Treatment  81 upvotes 2 years ago
      A hair loss treatment protocol involving topical and oral medications such as Minoxidil, RU58841, Finasteride, Dutasteride, Melatonin, Zinc, Vitamin B6, NAC, Caffeine, Biotin, Ginseng, and Semen; other treatments including Microneedling, Laser Helmet, Nizoral shampoo, Scalp Massage and supplements like Vitamin C, Vitamin D, Fish Oil, and Biotin; and the potential side effects of using this protocol.

      community 4.5 months of microneedling – progress

      in Microneedling  300 upvotes 4 years ago
      A user who has had positive results from using a regimen of microneedling, finasteride, minoxidil, peppermint oil, keto shampoo and DHT organic shampoo for hair growth. The conversation also addressed whether to use .5mg or 1mg of finasteride and the difference between dermapens and rollers.

      community Solvent for topical fin with low absorption

      in Product  2 upvotes 5 months ago
      The conversation is about using distilled water as a solvent for topical finasteride to reduce systemic absorption. The user is considering avoiding ethanol and propylene glycol to achieve this.

      community Ru with gloves because of Systemic absorption?

      in Research/Science  10 upvotes 1 year ago
      The conversation is about whether to use gloves when applying 5% RU58841 to avoid systemic absorption and if washing hands with water is sufficient. Users question the concern, noting it is applied to the scalp.

      community Can I mix finasteride in just water for topical?

      in Finasteride/Dutasteride  5 upvotes 2 years ago
      The conversation is about whether finasteride can be mixed with just water for a topical solution and if Isopropyl Alcohol and Propylene Glycol are necessary for effectiveness and faster drying. The user is seeking advice on the formulation of topical finasteride.

      community switched from topical to oral minoxidil (topical mixed with water) 3 months ago and aside from being much easier i’ve also had much more density overall. My results aren’t even finished yet!

      in Progress Pictures 2 years ago
      This user discussed using oral minoxidil as a hair loss treatment, and was cautioned against mixing topical minoxidil with water and drinking it due to potential side effects and risks. Other users shared their concerns about the dangers of self-prescribing medications without consulting a doctor.

      community RU58841 vehicle penetration (Study for minoxidil)

      in Treatment  12 upvotes 1 year ago
      The user mixes their own RU58841 solution and found that increasing the ethanol content improved absorption and reduced scalp itching. A study on minoxidil showed that penetration increased with higher ethanol concentrations, reaching maximum penetration at 90% ethanol.

      community Do not use oral dutasteride from Strut Health.

      in Finasteride/Dutasteride  29 upvotes 2 years ago
      The ineffectiveness of Strut Health's dutasteride capsules, which are filled with raw powder instead of liquid and don't contain any buffering agents that would allow for absorption into the bloodstream. It is suggested to use other brands of liquid-filled dutasteride capsules for better results.

      community Dermarolling for the next 4 months

      in Treatment  10 upvotes 5 years ago
      The user plans to dermaroll and use minoxidil for hair loss over the next 4 months, documenting progress monthly. They will also consider finasteride later and include vitamins, a custom shampoo, castor oil, scalp massages, and increased water intake in their regimen.

      community Is microneedling + minoxidil better than oral minoxidil

      in Chat  29 upvotes 1 month ago
      Oral minoxidil is considered more effective for hair regrowth than topical minoxidil, but it carries higher risks. Combining microneedling with topical minoxidil can enhance absorption, but oral minoxidil with microneedling shows significant results.

      community The "DHT" itch myth - it's more complicated

      in Product  7 upvotes 1 year ago
      A user found that scalp itch might be linked to inflammation rather than DHT alone and noticed hair improvement with certain cancer drugs. They also discovered that black seed oil relieved their scalp itch and are experimenting with a mix of essential oils for dry scalp, questioning if oils affect minoxidil absorption.

      community Are carbohydrates needed for hair growth

      in Research/Science  26 upvotes 4 months ago
      A 47-year-old male experienced significant hair loss after losing 37 kg in 6 months on a low-carb diet and started taking biotin, zinc, iron, selenium, and spectral dcn-n. Replies suggest that while carbs are not directly needed for hair growth, they help regulate hormones and nutrient absorption, and rapid weight loss can also contribute to hair loss.

      community Anything you use without scientific backing, just trusting your gut?

      in Research/Science  12 upvotes 2 years ago
      The conversation discusses using peppermint oil for hair loss, with one user applying it undiluted to the scalp and another combining it with finasteride and microneedling. Some believe in its effectiveness despite limited scientific evidence, and also mention rosemary oil as potentially beneficial.

      community Ultimate Stack without nuking your gender (you'll go broke)

      in Treatment  81 upvotes 1 month ago
      A hair loss treatment plan includes finasteride, dutasteride, RU58841, pyrilutamide, minoxidil, and microneedling to inhibit DHT and promote hair growth. It also recommends supplements like Reishi and Lion’s Mane mushrooms, and a shampoo with ketoconazole, caffeine, and melatonin.

      community Liquid minoxidil + pyrilutamide

      in Treatment  17 upvotes 2 years ago
      Potential treatments for hair loss, specifically the combination of liquid minoxidil and pyrilutamide, with some suggesting that adding finasteride may be beneficial.

      community 4 Months Results on Big 3.5

      in Progress Pictures  79 upvotes 4 years ago
      A 20-year-old male shared his 4-month hair regrowth results using finasteride, minoxidil, nizoral, and dermarolling. Commenters noted improved hair density and the potential for further progress.