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      community Why is dutasteride's volume of distribution so much bigger than finasteride? Is it more lipophilic and crosses barriers better?

       23 upvotes 1 year ago
      Dutasteride has a larger volume of distribution than finasteride due to its lipophilic nature, allowing it to concentrate in hydrophobic areas and making it difficult to excrete. A user experiencing hair loss has been using oral finasteride for 10 months with minimal regrowth and is considering switching to dutasteride or adding oral minoxidil.

      community Has anyone tried these? What was your experience?

      1 year ago
      A user is experiencing hair loss and is trying New Nordic Hair Volume gummies, which contain zinc, biotin, horsetail, and apple extract. Other users suggest that only minoxidil and finasteride/dutasteride are effective, and recommend testing for deficiencies before using supplements.

      community Minoxidil 5% + Finasteride 0.25% Foam - 1 week

       2 upvotes 1 year ago
      The user started a hair loss treatment using Minoxidil 5% and Finasteride 0.25% foam, along with ketoconazole shampoo and derma-stamping. After one week, they noticed stronger hair with more volume and a slight drop in libido.

      community Taking Charge of Your Hair: The "Big 3 Stack" Explained for 2023

       129 upvotes 3 years ago
      The "Big 3 Stack" for hair loss treatment, which includes Minoxidil for hair density improvement, Ketoconazole shampoo for enhancing hair volume and thickness, and Finasteride for blocking hair loss causing hormones. Microneedling can boost Minoxidil's effects.

      community (37 M) Fin for 5 o years, Dut for 9 months. I’d like to talk to Dut’s manager

      in Progress Pictures  138 upvotes 1 year ago
      A 37-year-old male has been using finasteride for 5 years and dutasteride for 9 months to address hair loss, noticing improvements but also some recent thinning. He experienced no significant side effects from either treatment, except a slight decrease in semen volume with dutasteride, and is considering trying oral minoxidil again despite previous side effects.

      community This is my one year of experimental supplemention for my hair:

      2 years ago
      The user found Merz Spezial capsules to be the most effective supplement for improving hair volume and reducing hair loss over a year. Other users suggest using finasteride and minoxidil for better results against male pattern baldness.

      community currently active protocols, working so far

      3 years ago
      The conversation is about a person's hair loss treatment routine, which includes Metformin, sleep in darkness, avoiding EMF at night, Nizoral, Dermarolling, Castor oil, and Collagen. They have observed less hair shedding and increased hair volume.

      community Update after 15 years on finasteride and 4 on dutasteride

       210 upvotes 1 week ago
      A 55-year-old male has been managing hair loss with finasteride for 15 years and switched to dutasteride in 2022 due to thinning. He also uses minoxidil, PRP treatments, and ketoconazole shampoo, and is considering a shorter hairstyle for more volume.

      community The curious case of John Cazale’s hair

      in Satire  322 upvotes 5 months ago
      John Cazale's hairline showed strong recession at the temples but maintained solid volume and density, sparking discussion on different hair loss patterns and the importance of overall hair density. Treatments like Minoxidil and Spironolactone were mentioned as potential factors in maintaining hair, though genetics and styling were also considered significant.

      community My experience with finasteride and outlook on hairloss

       13 upvotes 5 years ago
      The user started finasteride at 21.5 years old and saw significant improvement in hair volume and maintenance of the hairline, though some recession continued. They are optimistic about future hair loss treatments like CRISPR and are not currently using additional treatments like minoxidil or derma-rolling.

      community 9 months of treatment as an aggressive diffuse thinner

       67 upvotes 4 months ago
      The user has been using oral minoxidil, dutasteride, RU58841, and other treatments for hair loss over nine months, seeing some improvement in hair thickness and crown volume but continued thinning at the hairline. They plan to continue treatment for another nine months despite being sensitive to DHT fluctuations and are considering increasing dosages or other options like a hair transplant.

      community One year on minoxidil, one month on finasteride

       127 upvotes 8 months ago
      A 25-year-old has been using topical minoxidil for one year and oral finasteride for one month to combat hair loss, with no side effects from finasteride so far. The user reports that minoxidil has helped maintain their hair, with some improvement in temple volume, and is considering adding dermarolling.

      community Anyone had similar experience ?

       4 upvotes 8 months ago
      The user experienced rapid diffuse hair thinning and is questioning if a vitamin D level of 32 could be the cause. They noticed a sudden loss of hair volume and density over 1-2 months.

      community Anyone used Copper Peptide yet?

       5 upvotes 3 years ago
      Copper peptide topical is being discussed for hair health, with some users noting it may improve hair volume. There is uncertainty about its effectiveness against hair loss.

      community 10 months progress pictures oral min+fin. It worked!

       267 upvotes 8 months ago
      A 24-year-old male experienced significant hair regrowth after 10 months of using oral minoxidil and finasteride chewables from Hims, with no side effects. He noticed increased hair volume, especially at the front, and recommends trying the medication for hair loss.

      community If sea salt spray makes thinning worse, then what?

       7 upvotes 1 year ago
      Sea salt spray may not be ideal for thinning hair, and alternatives like texture powder, thickening tonic, and styling clay are suggested for volume without damage. Some users recommend thickening sprays or mousse for a fuller appearance, while others suggest considering medication for hair loss.

      community Hair Loss “Cure” for Inflammation: Topical Roflumilast

      in Research/Science  32 upvotes 8 months ago
      Topical roflumilast is effective for reducing inflammation in various scalp conditions like seborrheic dermatitis, psoriasis, and eczema, but not proven to stop scarring alopecia. Alternatives like apremilast and Vtama are also discussed for their anti-inflammatory benefits.

      community Hair loss continues after 1mg fin daily

      in Finasteride/Dutasteride  6 upvotes 4 years ago
      The user has been using finasteride 1mg daily, minoxidil once daily, and various oils but continues to experience hair loss. They are considering whether to increase the finasteride dosage or maintain the current regimen until a hair transplant.

      community Hair loss mental effect is so bad

      in Satire  177 upvotes 1 year ago
      Hair loss negatively affects mental health, causing anxiety and depression. Minoxidil and finasteride are discussed as treatments, but side effects and mental health concerns remain.

      community Is it worth using anti-hair loss shampoo?

      in Product  2 upvotes 7 months ago
      Anti-hair loss shampoos, like the one with rosemary, quillaja, and jaborandi extracts, mainly support scalp health but are not effective for hair regrowth compared to treatments like finasteride or minoxidil. Ketoconazole 2% is noted as the only effective anti-hair loss shampoo, while others are often considered scams.

      community Hair loss treatments rated (by gpt-4)

       249 upvotes 3 years ago
      Rating treatments for hair loss, with the help of GPT-4, according to efficacy, evidence and tolerability; a combination of chemicals from research papers, custom compounds, and some suggestions from other users were included.

      community HELP: Hair shedding/loss advice?

      1 week ago
      A 26-year-old woman is experiencing significant hair loss and thinning over the past few years, possibly linked to hair dye, keratin treatments, and a curly hair routine. She has tried spironolactone for acne without success in stopping hair shedding and is seeking advice on regrowing her hair.