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GlossaryBlisters (Vesicle)

fluid-filled sacs on skin from friction, burns, or infections

Blisters, also known as vesicles or bullae depending on their size, are fluid-filled sacs that form on the skin due to friction, burns, infections, or other causes. They act as a protective barrier, allowing the underlying tissue to heal. Vesicles are typically smaller than 0.5 centimeters, while bullae are larger.

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community Hair repigmentation of poliosis circumscripta in androgenetic alopecia patient treated with exosomes and fractional picosecond laser

in Product 2 upvotes 9 months ago

Exosomes combined with fractional picosecond laser treatment were effective in treating androgenetic alopecia and promoting repigmentation in white hair patches. The role of exosomes in hair repigmentation, particularly in conditions like poliosis, is not well-studied.

community My Testosterone results before and after Finasteride

in Update 146 upvotes 3 years ago

Finasteride significantly increased testosterone levels for the user, with no major side effects except watery semen, which was resolved with zinc supplements. The user's hairline stopped receding and slightly improved.

community Peptides that Stop Hair Loss? | In-depth Literature Review Video

in Research/Science 74 upvotes 5 months ago

Peptides like TB500, KPV, GHK-CU, and BPC-157 are overhyped for hair growth with limited proven effectiveness in humans. Combining peptides with delivery methods like iontophoresis and sonophoresis shows promise, but many claims remain unproven.

community How to know if shedding is from tren or minoxidil?

in Minoxidil 5 upvotes 8 months ago

The user started using trenbolone and minoxidil simultaneously and experienced increased hair shedding, unsure which is causing it. Replies suggest both drugs could cause hair loss, with one advising to stop trenbolone to protect hair and another indicating minoxidil is unlikely the cause due to the timing.

community Topical Finasteride Doesn't Directly Reduce 5ar Enzyme on Scalp

in Finasteride/Dutasteride 72 upvotes 1 year ago

Topical Finasteride doesn't directly reduce 5ar enzyme on scalp and has the same mechanism as oral, needing to go through the liver. Users debate the accuracy of this information and discuss various studies and experiences.

community Long term finasteride users; Did you notice any improvement after 2 years?

in Finasteride/Dutasteride 14 upvotes 1 year ago

Long term Finasteride users and whether or not they have noticed improvements after two years of use, with other treatments such as Minoxidil and dermarolling also discussed. Some replies suggest that improvement is possible even beyond the two year mark while others caution against believing studies backed by the Post-Finasteride Foundation.

community PSA: Most men who stay on Fin will see the sexual side effects go away. Stop the fear mongering

in Finasteride/Dutasteride 191 upvotes 2 years ago

Finasteride can cause sexual side effects in less than 2% of men, but these often disappear over time, even if the treatment continues. Some users report persistent side effects, while others experience no issues or only temporary ones.

community Would there be ANY reason to still take 5AR inhibitors if pyrilutamide does what is intended?

in Research/Science 19 upvotes 2 years ago

A potential new treatment for hair loss, Pyrilutamide, and the discussion of whether or not people should still be taking traditional treatments like Minoxidil and Finasteride with it.

community I am having Success with RU58841 and 1mm Derma Roller

in Microneedling 19 upvotes 2 years ago

A user reported success with RU58841 and a 1mm derma roller for hair regrowth, noting significant improvement in hair density and reduced scalp visibility. They also mentioned using minoxidil and black castor oil in the past, with mixed results.

community New and Interesting HairLoss Studies/Papers/Reviews

in Treatment 42 upvotes 4 years ago

Hair loss treatments discussed include Dutasteride with Ketoconazole, tissue engineering strategies, and androgenetic alopecia therapies. Massage doubles follicular retention, improving treatment effectiveness.

community What solution to use for RU58841?

in Product 1 upvotes 1 year ago

The post is about using different solutions for RU58841, a treatment for hair loss. The user is asking for opinions on the effectiveness of different vehicles and dosages.

community Estimate of GT20029 on the grey market?

in Technology 9 upvotes 1 year ago

The conversation is about when GT20029, a hair loss treatment, might be available on the grey market, with users discussing the challenges of compounding it and speculating it might be available after phase 2 results, similar to pyri. Specific treatments mentioned are pyri, RU58841, and GT20029.

community RU58841 vehicle penetration (Study for minoxidil)

in Treatment 12 upvotes 1 year ago

The user mixes their own RU58841 solution and found that increasing the ethanol content improved absorption and reduced scalp itching. A study on minoxidil showed that penetration increased with higher ethanol concentrations, reaching maximum penetration at 90% ethanol.

community 2 years of fin, 1.5 years of minoxidil, calling it quits. Thank you.

in Shaved/buzzed 567 upvotes 1 year ago

This user has been struggling with hair loss for the past two years and attempted to treat it using finasteride and minoxidil. Despite their efforts, they have not seen any improvement in their condition, so they have decided to shave or buzz their head instead. Others gave advice on other treatments that could be tried if desired.

community Does melatonin dissolve in isopropyl alcohol

in Technology 7 upvotes 1 year ago

The conversation discusses making a topical melatonin solution for hair loss treatment, questioning if isopropyl alcohol can dissolve melatonin. Melatonin is soluble in lipids and alcohol, but it's unstable and should be mixed fresh regularly; it may help hair growth by affecting certain cellular signaling pathways and has anti-androgenic effects.

community Is it true if you have inflammation on scalp meds won’t work?

in Chat 11 upvotes 6 months ago

Inflammation on the scalp can hinder hair regrowth and the effectiveness of treatments. The user is using ketoconazole shampoo, Selsun Blue, finasteride, and oral minoxidil.

community Is Anyone using Latanoprost at all?

in Product 9 upvotes 8 months ago

A user discusses using latanoprost, a costly treatment that may extend the hair growth phase and improve hair quality, wondering why it's not more popular. They already use a combination of finasteride and minoxidil and plan to incorporate latanoprost into their routine.

community Solution vehicle used by compounding pharmacy

in Research/Science 1 upvotes 1 year ago

The user is using 0.1% dutasteride, 1% minoxidil with 2% procapil and 0.005% caffeine in the morning, and 1% minoxidil with 2% procapil and 0.01% tretinoin at night. They are concerned about the solution vehicle's effectiveness in preventing systemic absorption and ensuring the products stay around the hair follicles.

community Protac degradation of the androgen receptor in mice shows good efficacy and no systemic drug could be found

in Research/Science 47 upvotes 1 year ago

The efficacy of degrading the androgen receptor through dermal application in DP cells, a delivery system for topical drugs that involves dissolving microneedles, and rosemary oil as an alternative anti-androgen.

community Dr Kyle Gillett on topical Dutasteride

in Finasteride/Dutasteride 56 upvotes 2 years ago

The potential effectiveness of topical dutasteride, as well as other hair loss treatments such as finasteride, RU58841, minoxidil, and various vitamins. Experiences from users who have used these treatments were shared.

community Does anyone know where to buy adenosine shampoo or conditioner in the uk?

in Product 2 upvotes 2 years ago

Seeking adenosine shampoo or conditioner in the UK without minoxidil. Topical adenosine solution also considered.

community No side effects on pyrilutamide / KX-826 so far

in Research/Science 207 upvotes 3 years ago

User TopBack56 and friends tried pyrilutamide (KX-826) for hair loss without experiencing negative side effects. They observed fine vellus hairs but no thick hair growth yet, and plan to add GT20029 to their regime after safety trials.

community CB-03-01: I need help

in Treatment 7 upvotes 3 years ago

The user stopped using finasteride and RU58841 and is considering CB-03-01 for androgenic alopecia but is concerned about the cost and effectiveness, especially at a lower dose than in clinical trials. They are also using minoxidil, micro-needling, and nizoral shampoo but are unsure about the correct application method for CB-03-01.

community Heating foam minoxidil into a liquid?

in Minoxidil 18 upvotes 4 years ago

Heating foam minoxidil into a liquid for easier application and quicker drying. Effectiveness remains the same as liquid minoxidil.

community The safest way to use finasteride - my research

in Finasteride 24 upvotes 7 years ago

The post discusses microdosing finasteride to minimize side effects while treating hair loss. The user also mentions using minoxidil, biotin, and ketoconazole.

community We need actual hair loss studies on Epristeride

in Research/Science 6 upvotes 1 month ago

Epristeride is a selective 5 alpha reductase type 2 inhibitor that may reduce scalp DHT similarly to finasteride, with potentially fewer side effects. It is suggested that combining epristeride with finasteride or dutasteride could enhance hair loss treatment effectiveness.

community So we have 20k dollars human like machines available but no new effective treatment for hairloss since finasteride :)

in Chat 237 upvotes 2 months ago

There have been no new effective hair loss treatments since finasteride, despite technological advancements. Current treatments include finasteride, minoxidil, and RU58841, with ongoing challenges and potential future solutions in research.

community Hair follicle cloning is already possible

in Chat 38 upvotes 2 months ago

Hair follicle cloning is claimed to be possible but not widely available due to potential safety issues, such as cancer risks. Current treatments like finasteride and dutasteride are not effective for everyone, and there is frustration over limited access to these medications.

community This sub after taking Finasteride for one day

in Satire 907 upvotes 4 months ago

The conversation humorously discusses the side effects of finasteride, particularly sexual dysfunction. Users share mixed experiences, with some reporting issues and others not.

community Warning: Your Rogaine Foam Might Not Contain Minoxidil

in Minoxidil 373 upvotes 5 months ago

A user experienced significant hair loss after using Rogaine foam purchased from Amazon, which failed a bleach test for Minoxidil. They discovered that even legitimate Rogaine products might be faulty and advised buying from reputable sources.