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GlossaryEpidermis (upper dermis)

outermost skin layer providing protection against environmental factors

The epidermis is the outermost layer of the skin, serving as a protective barrier against environmental factors such as pathogens, UV radiation, and physical injury. It is composed of multiple layers of cells, primarily keratinocytes, which undergo a continuous process of renewal and shedding. This layer also contains melanocytes, which produce melanin, the pigment responsible for skin color.

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community What are the chances I do more harm than good with microneedling?

in Microneedling 18 upvotes 1 year ago

The user reported progress with hair regrowth using a topical solution combining finasteride and minoxidil, but experienced scalp irritation which improved after adjusting the treatment. They are considering microneedling but are concerned about the risk of scarring.

community I started rapidly diffuse thinning at 22. I'm 42 now and have as much hair as I did at 16. AMA

in Treatment 445 upvotes 4 years ago

Hair loss treatments like finasteride, minoxidil, ketoconazole, PRP, and microneedling helped maintain hair for 20 years. Research and try evidence-based treatments for best results.

community 24 weeks of treatment. Best decision of my life

in Progress Pictures 918 upvotes 2 weeks ago

A 32-year-old male used 1.25mg oral finasteride daily and 1ml topical minoxidil twice daily for 24 weeks, experiencing improved skin and hair growth with initial side effects that resolved after three weeks. He plans to try dermastamping to address a stubborn cowlick area.

community 4 months on fin, min and micro. 20M

in Progress Pictures 63 upvotes 11 months ago

A 20-year-old has seen positive results for hair loss after 4 months using 1 mg finasteride daily, minoxidil twice daily, and weekly dermastamping with a 1.5 mm needle. They also used ketoconazole shampoo initially and recommend starting treatment early.

community Success sttory – 22 to 27

in Progress Pictures 4 years ago

A user's success story of improving their hair loss with treatments that include finasteride, dutasteride, minoxidil, nizoral, and dermastamping; other products that have been tried with varying results; and potential side effects.

community M22 1 year 4 months topical min + oral fin

in Finasteride/Dutasteride 216 upvotes 1 year ago

A user's experience with hair loss treatments, specifically Minoxidil (topical) and Finasteride (oral), over a period of 1 year and 4 months. The user reported best results after 6 months, a significant hair shed 4 months ago, and current regrowth, while also using a 1.25mm dermastamp. The user adjusted Finasteride dosage over time and experienced high testosterone and nipple sensitivity.

community What's the general consensus on microneedling here?

in Microneedling 21 upvotes 5 months ago

The conversation discusses microneedling for hair loss, focusing on optimal needle depth and frequency. Users report varying practices, with some using Minoxidil after microneedling and others suggesting different depths and frequencies based on personal tolerance.

community Why should more people explore the "new frontiers" of treatment (Megathread).

in Treatment 7 upvotes 2 months ago

The conversation discusses exploring new hair loss treatments beyond popular ones like Finasteride, Minoxidil, and Ketoconazole. Specific treatments mentioned include ozone therapy, Dutasteride mesotherapy, RegeneraActiva, microcurrent electrical hair stimulation, Nourkrin, and BioEqua Enercharger.

community PCOS female who posted before; saw Endo today. prescribed spironolactone and minox 5%

in Update 1 upvotes 1 year ago

PCOS female visited doctor for hair loss concerns, prescribed spironolactone and minox 5%. Doctor advised against finasteride or dutasteride, user considering self-medication with dutasteride.

community What other factors than DHT causes hair loss – and what to do about it?

in Treatment 2 years ago

Factors that can cause hair loss other than DHT, such as inflammation and diet, and potential treatments like scalp massages, minoxidil, citrulline, stretches, meditation, iron sulfate/Vitamin C, Vitamin D, protein and Dutasteride.

community The no BS guide to saving your hair without finasteride (improvement in 90% of patients in the study) with a low side effect profile or improvement in 100% of patients but a higher side effect profile and increased dosage. The future is here?

in Minoxidil 92 upvotes 4 years ago

Hair loss treatments, specifically the use of oral minoxidil in combination with micro-needling. Oral minoxidil has been found to improve hair density in 90% of patients with a low side effect profile, but using 5mg per day can result in higher side effects including hypertrichosis and edema. Other treatments mentioned include finasteride and RU58841.

community 9 months of minoxidil , finasteride, spironolactone, estradiol

in Progress Pictures 64 upvotes 4 months ago

User shared progress pictures after 9 months of using minoxidil, finasteride, spironolactone, and estradiol for hair loss. Significant regrowth was noted, especially after starting estradiol.

community My 6months progress (good thing I caught it early)

in Progress Pictures 52 upvotes 9 months ago

After 6 months of using 1mg finasteride daily and ketoconazole shampoo twice a week, an individual saw hair loss improvement. They also maintain a good diet and regular gym routine but do not train their calves.

community Just started my journey, wish me luck

in Product 97 upvotes 2 years ago

A user's journey to treat hair loss with a combination of oral medication, topical treatments, microneedling and different shampoos and supplements. It includes warnings about an OGX biotin shampoo potentially causing further hair loss.

community Dutasteride Mesotherapy Works – Just 1 month results

in Progress Pictures 109 upvotes 2 years ago

The effectiveness of using dutasteride mesotherapy as a hair loss treatment, with other protocols such as microneedling, vitamin D and B12, zinc, and biotin. The user's results were positive after 4-6 months without any serious side effects.

community The theory that explains everything. Please help me make this big!

in Research/Science 2453 upvotes 3 years ago

The post and conversation are about the role of the enzyme 3alpha-hydroxysteroid reductase in hair loss and the potential of compounds like procyanidin B2 and sulforaphane to boost its activity for hair regrowth. Further research is needed to develop effective treatments based on this theory.

community 1 Year progress on topical fin and min

in Progress Pictures 735 upvotes 3 years ago

User shares 1-year progress using topical finasteride and minoxidil for hair loss, with positive results. Some users discuss trying topical dutasteride and varying dosages, while others share their experiences and ask about specific products.

community 6 month hairline results (dutasteride and microneedling)

in Progress Pictures 799 upvotes 4 years ago

A user's 6 month hairline results from using dutasteride and microneedling, which resulted in successful regrowth of their thinning temples. Other users commented with similar experiences that were also achieved through the use of finasteride, dutasteride and minoxidil.

community Discussion on Finasteride and life.

in Chat 162 upvotes 1 month ago

Finasteride can aid hair regrowth but may cause side effects like depression and sexual dysfunction. Users discuss experiences with finasteride, minoxidil, and RU58841, highlighting varied responses and the importance of informed treatment choices.

community Have been on treatment for close to two years, need to know if I should continue or take dut

in Progress Pictures 52 upvotes 2 months ago

A 22-year-old male has been using finasteride, topical minoxidil, and oral minoxidil for hair loss but sees minimal improvement and is considering adding dutasteride. Users suggest additional treatments like dermarolling, PRP, and consulting a dermatologist, or considering a hair transplant.

community The grim reaper won some battles, but I won the war- 3 Month Progress (Hairline + Crown (21yo)

in Progress Pictures 170 upvotes 2 months ago

User shared 3-month hair loss progress using foam Minoxidil, finasteride, microneedling, and shampoos. They experienced side effects with oral Minoxidil but had success with topical treatments and finasteride.

community Medication works - First Pic June 2020

in Progress Pictures 684 upvotes 9 months ago

The user improved their hair loss using finasteride, switched to dutasteride, micro-needling, Nizoral shampoo, and changed from topical to oral minoxidil, resulting in thicker hair, eyebrows, beard, and body hair. Commenters are impressed with the transformation, some mistaking the before and after photos for different people, and the user reports no side effects from the treatments.

community Minoxidil seems logistically impossible and impractical to use

in Minoxidil 136 upvotes 1 year ago

The post discusses concerns about the practicality of using Minoxidil foam for hair loss, including the frequency of application, preparation, coverage area, and drying time. Responses suggest that missing a dose isn't detrimental, it can be applied once a day, it works on all hair areas, and it doesn't need to be perfectly dry before application.

community Almost 8 months. 40 years old. Owe it all to this sub.

in Progress Pictures 815 upvotes 1 year ago

A 40-year-old man successfully regrew his hair in 8 months using 0.5mg Dutasteride, 2.5 oral minoxidil, minoxidil foam twice a day, derma rolling/stamping twice a week, and retinol serum. The community praised his progress, asked about his routine, and shared their own experiences.

community What an amazing time to be alive

in Finasteride/Dutasteride 184 upvotes 1 year ago

The post discusses a user's experience with hair loss treatments, specifically topical finasteride, minoxidil, and micro-needling, and their plan to switch to oral versions and add Dutasteride. The conversation includes various responses, with some users sharing their own experiences and side effects, and others expressing desire for a more permanent hair loss solution.

community Ashton Kutcher talked about on the tonight show how he was quitting dut. Looks like the Norwood reaper has already come to collect.

in Satire 623 upvotes 1 year ago

The conversation is about Ashton Kutcher's hairline and how some people think it looks good for his age, while others criticize it. Some mention that he used to use medication for hair loss but stopped.

community Eliminating scalp itch leads to regrowth (and my RU58841 progress)

in Research/Science 61 upvotes 1 year ago

User experienced hair regrowth after eliminating scalp itch with RU58841. Others discussed itch and hair loss connection, and effectiveness of combining RU58841 with 5AR inhibitors.

community New study shows that microneedling is an ineffective hair loss treatment

in Research/Science 1 year ago

The effectiveness of microneedling as a hair loss treatment, with evidence from studies and anecdotal accounts from other users. It is suggested that combining microneedling with minoxidil or finasteride may be more effective than using microneedling alone, although some people have had success using only microneedling.

community Why do I see so many people here recommend microneedling?

in Microneedling 108 upvotes 1 year ago

The efficacy of microneedling for hair regrowth as either a stand-alone therapy or adjunct to Minoxidil, and whether Tretinoin is a safer and more effective option. Replies include personal accounts from users who have had success with microneedling in combination with minoxidil and peptide serums, as well as considerations of technique, depth, and potential scarring.

community Starting Pyrilutamide BID. First dose was yesterday. Diffuse thinning. I will put my full regimen below.

in Research/Science 89 upvotes 2 years ago

A user's regimen to help with their diffuse thinning, which includes taking Pyrilutamide BID, 1mg finasteride daily, 2.5mg oral minoxidil daily, topical minoxidil since August 2021, LLLT every two days, topical fin, progesterone, melatonin, minoxidil (started one week ago), pumpkin seed oil and not dermarolling; other commenters suggested Nizoral for dandruff control and caution when using pre-mixed products with Pyrilutamide.