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      community Clascoterone - Why are there so few posts if it’s already on the market?

      in Chat  34 upvotes 8 months ago
      Clascoterone is being discussed for hair loss, but its current acne formulation may not be suitable for scalp use due to potential skin irritation and lower dosage compared to Breezula. Users mention other treatments like finasteride, minoxidil, and pyrilutamide, with some expressing skepticism about clascoterone's effectiveness for hair loss.

      community What do your guys routine look like?

       5 upvotes 3 months ago
      People are using various treatments for hair loss, including minoxidil, finasteride, dutasteride, tretinoin, and RU58841. Some are experimenting with additional compounds like GhK-cu and are interested in future treatments like extended-release oral minoxidil.

      community What product does David Dobrik use

      in Chat  336 upvotes 1 year ago
      David Dobrik uses Minoxidil and possibly Finasteride for hair loss but applies them incorrectly. Users suggest he consider surgery due to his financial capability.

      community Minoxidil works only with Retinoic acid

       314 upvotes 1 year ago
      Minoxidil is more effective when combined with retinoic acid, such as tretinoin or tazarotene, enhancing hair growth. Some users experience significant regrowth, while others see minimal effects or side effects.

      community We already know how to permanently fix hair loss. The science is done. The only thing missing is the funding to run one experiment.

      in Technology  613 upvotes 4 months ago
      A permanent hair loss solution could involve reprogramming hair follicles to resist DHT using mRNA and siRNA. However, high costs, safety concerns, and the pharmaceutical industry's preference for ongoing treatments over one-time cures are major obstacles, with finasteride and minoxidil remaining standard treatments.

      community I had claude create a protocol only using fda approved drugs.

       4 upvotes 8 months ago
      A new hair loss protocol using FDA-approved topical treatments targets eight pathways, potentially improving results by 60-75% compared to the standard 40-50% from oral minoxidil and finasteride. The protocol includes minoxidil, finasteride, tacrolimus, cetirizine, bimatoprost, lithium gluconate, losartan, melatonin, NAC, caffeine, and tretinoin, with a monthly cost of $35-50 in Mexico and $80-150 in the US.

      community Chat is this real? Compound called clascoterone

       581 upvotes 9 months ago
      Clascoterone shows promising results for hair regrowth in men with androgenetic alopecia, with potential FDA approval by 2026. It acts as a topical androgen receptor blocker, offering a new treatment option with minimal side effects compared to existing treatments like finasteride.

      community Currently Trending Twitter Post: Clascoterone Hailed as New Cure

       1897 upvotes 9 months ago
      Clascoterone is being discussed as a promising new hair loss treatment, showing significant improvement in trials. Despite this, skepticism persists about its effectiveness, cost, and side effects, with some users preferring minoxidil and finasteride.

      community I just made 60x of 5mg minoxidil sugar cubes

       1339 upvotes 1 year ago
      A user created oral minoxidil sugar cubes due to lack of prescription access, leading to a humorous discussion about unconventional and potentially unsafe methods of using minoxidil. The conversation highlights the lengths people go to for hair growth.

      community DHT and 5AR respect post, it's importance within the brain

      in Research/Science  111 upvotes 2 years ago
      The conversation discusses whether to use finasteride for hair loss, considering its role in inhibiting DHT and 5AR, which can affect brain function and mood. Some users report anxiety and depression from finasteride, while others do not experience these side effects and emphasize the importance of DHT for brain and prostate health.

      community Where to get Tretinoin? UK delivery

      in Treatment  3 upvotes 1 year ago
      The conversation is about finding affordable tretinoin with UK delivery options. Users discuss a finasteride, minoxidil, and tretinoin spray from e-surgery and suggest other sources like Zing meds and Skinorac.

      community Winlevi 1% Cream - Lets See how it goes

       3 upvotes 1 month ago
      The conversation is about using Winlevi 1% cream, Pyri (Koshine) 0.5%, and minoxidil for hair loss treatment. The user is hopeful for results with Winlevi but is sensitive to 5AR blockers.

      community Question about ppl who use Hair+ me topical solution

      in Research/Science  4 upvotes 5 months ago
      Minoxidil and finasteride topical solutions may last longer than their labeled best before date, with users experiencing varying side effects and effectiveness over time. Some users report reduced side effects and increased hair loss towards the end of the second month of use.

      community RESULTS: 1% Clascoterone Cream. (3 months Jan-Mar 2026)

       18 upvotes 5 months ago
      The user reported slight improvement in hairline using 1% Clascoterone cream over three months but found it too costly to continue. They expressed interest in trying a 5% concentration if it becomes available at a reasonable price.

      community The urge to buy Clascoterone 5% solution

       11 upvotes 9 months ago
      Clascoterone 5% solution is not yet commercially available, with only the 1% solution currently sold for acne. Users discuss the potential of Clascoterone as a hair loss treatment, comparing it to other anti-androgens like RU58841 and Eucapil.

      community Clascoterone phase 3 results are out!

       80 upvotes 9 months ago
      Clascoterone phase 3 results show promising improvements in hair count, but concerns about high costs and lack of detailed data remain. Users compare it to existing treatments like Minoxidil and Finasteride, expressing skepticism about its accessibility and effectiveness.

      community Mix tretinoin into minoxidil bottle

      in Treatment  1 upvotes 1 year ago
      Mixing tretinoin with minoxidil for hair loss treatment. Some users prefer separate application or professional compounding due to potential solubility issues.

      community The expected timeline for PP405 - Next update at AAD Annual Meeting in March 2026 ?

       34 upvotes 8 months ago
      A new hair loss treatment, PP405, showed promising Phase 2a results with 31% of patients experiencing over 20% hair density increase without systemic absorption, avoiding hormonal side effects. The treatment is expected to be expensive, with Phase 3 trials starting mid-2026, and there is skepticism about the data's strength.

      community Topical min once a day and 0,5mg dut EOD

      in Progress Pictures  131 upvotes 9 months ago
      The user experienced significant hair regrowth after 7 months using topical minoxidil once a day and 0.5mg dutasteride every other day, with noticeable results in the last two to three months. They reported no side effects and did not use dermarolling.

      community Women complaining of bad effects from Winlevi (Clascoterone 1%)

       11 upvotes 9 months ago
      Women experienced severe reactions, including Topical Steroid Withdrawal (TSW), from using Winlevi (Clascoterone 1%) on their faces. Concerns were raised about the potential risks of higher concentrations, especially for hair loss treatment.

      community The amazing fast pace of PP405.

      in Chat  327 upvotes 11 months ago
      PP405 is a new hair loss treatment advancing quickly in trials, generating excitement and skepticism about its effectiveness and marketing claims. Some see it as a potential alternative to minoxidil and finasteride, but concerns about long-term effects and the need for DHT blockers persist.

      community Is Retinol effective by itself?

       4 upvotes 1 year ago
      Retinol is not effective alone for hair loss; tretinoin is more potent and sometimes mixed with minoxidil. Retinoids do not stop hair loss, and finasteride or dutasteride is necessary for that.

      community I will never more buy any hairloss traitements in public pharmacy

      in Minoxidil  420 upvotes 1 year ago
      A user was embarrassed by a pharmacist's loud mention of "minoxidil" for hair loss, sparking a discussion on the stigma and unprofessionalism. Users suggested online purchases or different pharmacies for privacy and reassured that most people don't notice others' purchases.

      community Are they going to Ban Finasteride in the EU ?

      in Finasteride/Dutasteride  68 upvotes 1 year ago
      There is concern about a potential ban on finasteride in the EU, but many believe it is unlikely unless serious side effects are found. Users rely on finasteride for hair loss and other health benefits, and a petition has been created to oppose any restrictions.