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      community For Those Thinking of Giving Up

      in Chat  32 upvotes 5 months ago
      A user shares their experience with hair loss treatments, including oral Dutasteride, topical Minoxidil, and Tretinoin, despite seeing no results after six months. They encourage others to continue treatments and consider options like oral Minoxidil, Nizoral shampoo, and possibly hair transplants.

      community 24M - Dut + Min not working. How cooked am I?

       3 upvotes 10 months ago
      A 24-year-old is struggling with hair loss despite using treatments like dutasteride, oral minoxidil, RU58841, and considering a hair transplant. They are advised to continue medication, possibly increase dosages, and explore additional treatments like tretinoin and tacrolimus.

      community Do not recommend topical finasteride after two years.

       117 upvotes 3 weeks ago
      Topical finasteride was ineffective for some users, leading to hair loss, while others found it beneficial. Alternatives like oral finasteride, dutasteride, minoxidil, and combinations with tretinoin and keto shampoo were suggested.

      community Trialing the probiotics BB536, PTA 6475 so you don’t have to

       75 upvotes 1 year ago
      Probiotics like L. reuteri ATCC PTA 6475 and B. longum BB536 may improve hair growth and density by reducing inflammation and reversing DHT damage. The user is trialing these probiotics personally, ordering them from the U.S. to Canada, and plans to continue if no adverse effects occur.

      community How much do we know about PTD-DBM?

       7 upvotes 8 years ago
      PTD-DBM is a Korean-developed treatment for hair loss, with limited information available and some users testing it personally. A user purchased PTD-DBM for $115 and plans to test it on their temples, but its effectiveness and authenticity remain uncertain.

      community Breezula / pyrilutamide vs topical fin / dut for added protection on TRT?

       2 upvotes 4 months ago
      A 35-year-old is considering Breezula, Pyrilutamide, or topical finasteride/dutasteride to protect against hair loss while on testosterone replacement therapy (TRT). They currently use finasteride, oral minoxidil, and dutasteride but experienced increased hair shedding with TRT.

      community ABS-201 Trial - What should I know going in

      in Research/Science  28 upvotes 6 months ago
      The conversation is about a user preparing to join the ABS-201 clinical trial for hair loss treatment, which involves a prolactin inhibitor. The user plans to update others on their progress if enrolled.

      community PTD-DBM Update: Q&A With Dr. Kang-Yell Choi

       15 upvotes 7 years ago
      PTD-DBM is being explored for hair regrowth by targeting CXXC5, with clinical trials expected after pre-clinical studies. Users express anticipation and skepticism about its effectiveness.

      community Breezula phase 3 results said to be released next month

       26 upvotes 1 year ago
      Breezula's phase 3 results are expected soon, with discussions on the effectiveness of androgen receptor antagonists like spironolactone and the potential of GT20029. Users express skepticism about new treatments and discuss the complexities of male pattern baldness, often relying on finasteride despite its side effects.

      community TH07 by Triple Hair entering phase III trial

      5 months ago
      A new topical treatment, TH07, combining finasteride, latanoprost, and minoxidil, is entering phase III trials with promising early results. Some users express skepticism, noting the treatment uses existing products.

      community Trial for TDM-105795 update from research office

       16 upvotes 2 years ago
      The trial for TDM-105795 has been completed, and it was in phase 2A. The discussion seeks input on the next phases, 2B or 3, based on safety and efficacy.

      community Potential role of TB-500 Thymosin Beta-4

       7 upvotes 1 year ago
      The conversation discusses hair loss treatments, specifically mentioning Minoxidil, finasteride, RU58841, and TB-500 Thymosin Beta-4. It critiques the credibility of biohacking claims.

      community (MTF 35) Results of 18 Months of HRT

       775 upvotes 8 months ago
      A transgender woman experienced significant hair regrowth after 18 months of hormone replacement therapy (HRT) with estrogen and bicalutamide. The discussion notes HRT's effectiveness for hair regrowth but warns against its use for cisgender men due to feminizing effects.

      community Any experiences with Ptd-dbm??

       8 upvotes 3 months ago
      The user experienced reduced hair loss using an online serum but found it too expensive and is seeking a vendor for ptd-dbm. They are also interested in KY19382 but are unable to find it.

      community The Breezula 539% headline is doing a lot of heavy lifting right now.

       16 upvotes 4 months ago
      Breezula shows promising results for hair loss, with one trial showing a 539% improvement and another 168%, but lacks combination data with treatments like minoxidil or dutasteride. Its mechanism differs from finasteride, potentially offering fewer side effects by blocking receptors locally at the follicle.

      community Oral PTD-DBM available online, worth giving a shot?

       4 upvotes 6 years ago
      Oral PTD-DBM was discussed as a potential hair loss treatment, but it was deemed ineffective in humans despite promising results in mice. The conversation concluded that trying it without VPA might be unwise.

      community Tresless Bingo - This sub in a nutshell

       269 upvotes 3 weeks ago
      The conversation humorously critiques common hair loss discussions, mentioning treatments like Minoxidil, finasteride, and RU58841. It highlights confusion over progress pictures, pet safety concerns, and unrealistic expectations for new treatments.

      community How much more risk does TRT really put on hair?

       2 upvotes 1 month ago
      TRT may increase hair loss, but using treatments like dutasteride, minoxidil, and RU58841 can help mitigate it. Individual responses vary, and some users report regrowth while others see stabilization or continued loss.

      community Peptide Therapy -> GHK-CU, ZN-Thumulin, PTD-DBM

       4 upvotes 2 years ago
      The conversation is about the use of peptide therapies for hair loss, specifically GHK-CU, ZN-Thymulin, and PTD-DBM. The user is seeking feedback on the effectiveness of these treatments from those who have tried them.

      community CB-03-01 / Breezula Personal Results

       17 upvotes 7 months ago
      The user shared their experience with CB-03-01 (Breezula/Clascoterone) for hair loss, noting reduced shedding and improved hair appearance but experiencing significant sleep disturbances and low energy due to HPA axis suppression. They decided to stop using it due to these side effects and are waiting for GT20029 as an alternative.

      community Starting trt had good come back from meds been on off user for years been fighting the good fight since my 20s I’m now 40. ( sorry for the pics but you get the idea dead bald thin hair to curly thick )

       1 upvotes 1 year ago
      The user is using testosterone replacement therapy (TRT) at 250mg per week and is concerned about hair loss, managing it with 0.5mg dutasteride daily, 2.5mg oral minoxidil, topical minoxidil, RU58841, and other supplements. They seek advice on whether increasing dutasteride dosage would help if hair loss resumes.

      community Experience with CB (Breezula)?

       4 upvotes 6 years ago
      CB 03 01 (Breezula) was tried for hair loss but showed no significant improvement, with issues in dissolving and application. Finasteride and dutasteride remain the most effective treatments, while minoxidil is also used; CB's effectiveness is questioned, and topical alternatives like bicalutamide are considered.

      community RootBioTec? Basil extract for hair growth

       3 upvotes 1 year ago
      RootBioTec, a basil hairy root extract, claims to reduce hair loss by 31% in two months by inhibiting 5α reductase II and stimulating hair follicles. There is limited independent information available about its effectiveness.