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      community Now That PP405 Hype is Gone What is Everyone Coping with as the Next Cure?

       41 upvotes 1 month ago
      People are discussing various hair loss treatments, including finasteride, minoxidil, RU58841, and new potential treatments like vdphl01, ABS-201, and KX-826. Some express hope in future developments like hair cloning and CRISPR, while others emphasize acceptance and sticking with current treatments.

      community DNA Trichotest reliable? & topical spironolactone for Cis males

       1 upvotes 1 year ago
      The DNA Trichotest is considered unreliable for predicting hair loss treatment responses, and topical spironolactone is questioned for its effectiveness and safety in cis males. Finasteride and Dutasteride are recommended as more reliable treatments for androgenic alopecia.

      community When could we expect pp405 to hit the market?

       31 upvotes 1 year ago
      PP405 is expected to finish Phase 2 trials in late 2025, with potential market availability around 2028-2029 if all goes well. Current treatments like finasteride and minoxidil are still popular, while new options like KX-826 and Breezula are anticipated soon.

      community Any chemists want to manufacture PP405 / JXL069? (Steps inside)

       89 upvotes 10 months ago
      The conversation discusses the synthesis and potential use of JXL069 and PP405 for hair loss treatment, with skepticism about their effectiveness and concerns about safety. Users mention that JXL069 has shown no results in hair growth, and there is confusion about its identity and effectiveness compared to PP405.

      community DUPA - Impossible to cure, so giving up

      in Update  3 upvotes 1 year ago
      The user diagnosed with DUPA tried treatments like dutasteride, finasteride, RU58841, and minoxidil without success and is considering a hair system. They hope for a future cure, possibly with PP405, and others suggest options like scalp biopsy and SMP.

      community I had GPT create a comparison of pp405 week 8 results vs Fin and Min

       1 upvotes 1 year ago
      PP405 shows significantly better early-stage hair regrowth results compared to minoxidil and finasteride, with 31% of users experiencing over 20% density increase in 4–8 weeks. Minoxidil and finasteride show minimal or no visible regrowth in the same timeframe.

      community can someone help me identify these pls

      in Treatment 10 months ago
      The user is experiencing diffuse thinning and inflammation despite using 2.5mg dutasteride daily, ciclopirox, and ketoconazole shampoos. They are considering treatments like hydroxychloroquine and JAK inhibitors due to suspected scarring alopecia and have faced challenges in obtaining a scalp biopsy.

      community I think its working…. (23 years old 3 month treatment)

      in Progress Pictures  89 upvotes 1 year ago
      A 23-year-old is using oral dutasteride, topical minoxidil with finasteride, PRP, and microneedling for hair loss treatment over three months, showing noticeable progress. Some users suggest caution with hormonal treatments and discuss the cost-effectiveness of PRP.

      community Ben Greenfield Podcast : CHK-Cu & C-60

       4 upvotes 5 years ago
      CHK-Cu (copper peptide) and C-60 (branched carbon chain) are discussed as potentially more effective than minoxidil for hair regrowth. Some users are skeptical about the claim that DHT isn't the root cause of hair loss, and others are trying these products to see if they work.

      community RT1640 - Gray Hair Reversal Recipe

       3 upvotes 4 years ago
      The conversation discusses a hair loss treatment formulation containing cyclosporin, minoxidil, and tacrolimus, and mentions ongoing research on hair color reversal. The treatment showed high efficacy in restoring hair color in trials with 40 to 50 people.

      community Min Non responder. Tretinoin to become responder?

       2 upvotes 10 months ago
      The user did not respond to minoxidil and is considering using tretinoin to improve results. They also explored finasteride, microneedling, adapalene, red light therapy, and oral minoxidil as potential treatments.

      community legit source for RU58841 in Germany?

       3 upvotes 8 months ago
      The conversation is about finding a legitimate source for RU58841 in Germany, with suggestions including Receptorchem and GeneTherica. Anageninc and Chemyo do not deliver to Germany.

      community Chinese source for pyrilutamide or ru8841 ?

       3 upvotes 11 months ago
      The conversation is about finding a reliable Chinese source for pyrilutamide or RU58841, ideally with a third-party Certificate of Analysis from Janoshik Analytical. The user is seeking recommendations for these hair loss treatments.

      community Bloodwork: what to test for?

       6 upvotes 6 years ago
      The user has been taking oral Finasteride and topical Essengen 6 Plus for hair loss and is experiencing increased depression. They plan to get bloodwork to check hormone levels and are seeking advice on which tests to include.

      community Clascoterone 12 months phase 3 result out

       42 upvotes 5 months ago
      Clascoterone is promising for hair loss, showing 24.5% improvement in satisfaction compared to placebo. Users consider it an alternative to finasteride, with concerns about absorption and side effects.

      community Update on PP405 Trails - Pelage

       14 upvotes 7 months ago
      The conversation discusses interest in participating in PP405 trials for hair loss treatment, with users expressing uncertainty about eligibility due to location. Participants are eager for updates and willing to pay for shipping if trials are limited to America.

      community Hair Loss Inflammation Prevention Stack

       48 upvotes 1 year ago
      The conversation discusses a hair loss and scalp care routine involving ciclopirox shampoo, benzoyl peroxide, clindamycin gel, clobetasol propionate, and calcipotriol to manage seborrheic dermatitis, folliculitis, and inflammation. It also touches on the role of diet and other treatments like oral minoxidil and pioglitazone for scalp health.

      community Sooo whats the consensus about pp405 now?

      in Chat  75 upvotes 5 months ago
      PP405 may help with hair regrowth, especially when combined with minoxidil and finasteride, but its long-term effectiveness is unclear. Phase 3 trials are expected to begin soon, with results in a few years.

      community Stopping finasteride for chemo

      in Finasteride/Dutasteride  108 upvotes 1 year ago
      A user diagnosed with lymphoma is advised to stop finasteride during chemotherapy, with suggestions to consider treatments like Dutasteride and Minoxidil post-recovery. The focus is on prioritizing health over hair loss, with encouragement and advice from others who have experienced similar situations.

      community Will PP405 render Minox and Fin obsolete?

       30 upvotes 1 year ago
      PP405 might make minoxidil unnecessary, but finasteride or other 5AR inhibitors may still be needed. PP405 is expected to be expensive and not available until at least 2028, with limited information on its effectiveness.