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GlossaryTotal Antioxidant Capacity (Total Antioxidant Status)

measure of a sample's ability to neutralize free radicals

Total Antioxidant Capacity (TAC) is a measure of the combined antioxidant effect of all the compounds present in a sample, such as blood, food, or tissue. It reflects the ability of these compounds to neutralize free radicals, which are unstable molecules that can cause cellular damage and contribute to aging and diseases. TAC is important in both research and clinical settings to assess the antioxidant status and potential health benefits of various substances.

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community Looks like a real cure to the root of baldness (DHT-induced senescence) was proven earlier this year

in Research/Science 732 upvotes 2 years ago

A study that outlines the full model for androgenic alopecia (AGA) which links DHT to cellular senescence in dermal papilla cells, and suggests black chokeberry as a source of cyanidin 3-O-arabinoside polyphenol with potential anti-oxidant properties that could reverse this process. The post encourages reaching out to experts in anti-aging and longevity to research treatments involving the polyphenol.

community Have people with aggressive balding genetics genuinely had any results after applying any natural remedies ie:rosemary oil,coconut oil,Onion Juice etc

in Research/Science 42 upvotes 1 year ago

Natural remedies like rosemary oil, coconut oil, and onion juice are generally seen as less effective compared to medical treatments like finasteride, minoxidil, and microneedling. Some users believe natural oils can help, but modern medicine is often more reliable.

community People need to start accepting that only medical therapy (Fin/Dut) can save your hair in the long run.

in Treatment 112 upvotes 10 months ago

Minoxidil can regrow hair but doesn't address the underlying issue of DHT, leading to continued hair loss. Users discuss their experiences with finasteride and dutasteride, mentioning side effects, personal outcomes, and alternatives like microdosing topical finasteride.

community Started aggressively losing my hair at 16 and I'm now 30

in Progress Pictures 835 upvotes 1 year ago

The user started losing their hair at 16 and got a hair transplant. They used Minoxidil and finasteride as treatments. The transplant has held up well and they have not experienced graft loss.

community Got a microscope camera. Here’s the difference between healthy and miniaturized hair

in Progress Pictures 492 upvotes 2 years ago

A user who shared progress pictures of their scalp using a microscope camera, demonstrating the difference between healthy and miniaturized hair. Various explanations for the cause of this were discussed, such as DHT build-up in scalp sebum causing an autoimmune response leading to inflammation and eventual hair loss, with some suggesting a do-it-yourself treatment involving adding ascorbic acid powder to shampoo.

community My Theory Regarding a Cause and Cure for Androgenetic Alopecia

in Treatment 98 upvotes 4 years ago

Hair loss theory suggests imbalance between Vitamin D Receptor (VDR) and Androgen Receptor (AR) activation. Proposed treatment includes upregulating VDR, downregulating AR, and improving mitochondrial health.

community 15 months total on Dut/Min/RU and microneedling 1mm every other week

in Progress Pictures 1746 upvotes 2 months ago

The user reported significant hair improvement over 15 months using dutasteride, minoxidil (oral and topical), RU58841, ketoconazole, and microneedling. They are considering a hair transplant in 4-6 months.

community It’s time for total war on hair loss.

in Treatment 26 upvotes 1 year ago

A user's experience with hair loss, their attempts to treat it using topical minoxidil and finasteride, and other suggested treatments such as oral minoxidil and finasteride. Replies included advice against wasting time or money on scalp massages or oils.

community Uptade 3 Months after (6 months total)

in Update 11 upvotes 1 week ago

The user reports using finasteride, topical minoxidil, ketoconazole shampoo, and a dermaroller for hair loss. They notice more hair growth, but doubt full regrowth on the crown.

community ‏My recovery journey is a total of 12 months. Fin,min

in Progress Pictures 742 upvotes 2 months ago

A 36-year-old user shared their 12-month hair recovery journey using oral Propecia, topical minoxidil, a derma roller, ketoconazole shampoo, biotin, and omega-3. They reported seeing results by the second month, with some setbacks but overall progress.

community 2 months of difference with estradiol and spiro (4 months total w/ estradiol & spiro; 4 years of minoxidil and finasteride) (you should not take estradiol or spiro if you look manly and want to continue looking manly)

in Transgender 115 upvotes 1 month ago

Hair regrowth using estradiol, spironolactone, minoxidil, and finasteride, showing significant improvement over four years. HRT is not advised for cis men solely for hair loss due to feminizing effects.

community Update 7 months post op HT from Dr.Serkan Aygin 3100 total grafts…Topical Fin/Min + Men’s Viviscal,Biotin and it’s a 10 sulfate free shampoo mixed with Nizoral and I added donor area photos too this time. Enjoy and wish you the best.

in Transplants 53 upvotes 1 year ago

A 7-month update from Markoj44 regarding their hair transplant results, which includes the use of topical finasteride and minoxidil in combination with Viviscal, biotin, Nizoral shampoo, and donor area photos. People responded positively to the post.

community Is CosmeRna a scam? Terminal hair count vs Total hair count.

in Treatment 12 upvotes 1 year ago

The conclusion of the conversation is that CosmeRna may not be an effective treatment for hair loss compared to topical minoxidil 2%. It is suggested to wait for more reviews before purchasing it.

community Reddit’s Amatorial microneedling meta analysis of 11 different Clinical studies for a Total of 559 patients (Scalp microneedling + topical minoxidil 5%, safety, efficacy and Ideal protocol)

in Microneedling 329 upvotes 2 years ago

Microneedling with 5% minoxidil improves hair growth for hair loss patients. Best protocol: 1.5mm dermaroller weekly for 12 weeks or 0.6mm dermapen every 2 weeks for 12 weeks, skipping topicals for 24 hours.

community 4 month progress update. hair transplant, 1000 grafts each temple, plus 1000 grafts on crown (3000 total). I take oral oral dutasteride + topical minoxidil daily since the surgery

in Progress Pictures 28 upvotes 1 year ago

A hair transplant surgery involving 3000 grafts and the daily use of oral finasteride and topical minoxidil for four months since that procedure.

community Apparently finasteride lowers Free Testosterone?

in Finasteride 20 upvotes 6 years ago

Finasteride raises total testosterone but lowers free testosterone, which is important for male health. Users report mixed experiences with their fitness levels and blood test results after using finasteride.

community Using Topical Minoxidil And Pyrilutamide Together

in Treatment 1 upvotes 3 months ago

Mixing 1ml of topical Minoxidil and Pyrilutamide (2ml total) together in a container and applying immediately is being discussed. The concern is whether this method degrades or compromises the efficacy of either compound.

community About Pyrilutamide Phase II US Trial

in Research/Science 11 upvotes 1 year ago

The conversation discusses the comparison of Pyrilutamide Phase II US trial results with 1 mg finasteride for hair loss treatment. It mentions that the total hair count increase in the US trial was not as good as the China trial.

community H as anyone done sperm/fertility test before and after staring finasteride?

in Finasteride/Dutasteride 7 upvotes 4 years ago

The conversation discusses the impact of finasteride on sperm, including potential side effects like decreased ejaculate volume and total sperm count. Users share experiences and concerns about fertility tests before and after starting finasteride.

community Had a hair transplant with Dr. Feriduni - 6850 grafts (6000 from scalp, 850 from chest/beard)

in Progress Pictures 447 upvotes 11 months ago

A user had two hair transplant surgeries, using a total of 6850 grafts from the scalp, beard, and chest, costing around $20,000 USD, and is happy with the results, though the crown may not be as dense as the hairline. They experienced no scarring from the donor areas and noted that transplanted beard and chest hair are thicker and curlier.

community RU58841 and impact onmale fertility?

in Chat 2 upvotes 4 months ago

The conversation is about the potential impact of RU58841 on male fertility, specifically regarding sperm concentration, total count, and motility. The user is curious about the likelihood of RU58841 reducing fertility based on its mechanism of action and comparisons to similar substances.

community What blood markers to get tested before starting any 5-AR inhibitor?

in Treatment 4 upvotes 6 months ago

The conversation is about which blood markers to test before starting a 5-AR inhibitor for hair loss. The user mentions already testing Total T, Free T, SHBG, Estradiol, Haematocrit, Red blood cell count, and White cell count, and asks if DHT or additional markers are needed.

community Before and After - My journey so far

in Progress Pictures 575 upvotes 7 months ago

A 28-year-old used oral finasteride and minoxidil, and underwent two hair transplants in Turkey, with a total of 3150 grafts, resulting in a natural-looking hairline. The first procedure cost £3300, and the second was a free touch-up, with additional costs for flights and accommodation.

community How much do you pay a Month for your Medication?

in Treatment 6 upvotes 2 months ago

The user spends around 200€ monthly on hair loss treatments, including Kx826, Alfatradiol, Minoxidil, Nizoral Shampoo, Stemoxydine, Tretinoin, and a Dermastamp. The total cost is approximately 220$.

community Topical Dutasteride - Non-Hormonal, Side Effect Free 5ARI

in Finasteride/Dutasteride 26 upvotes 3 months ago

The conversation discusses the effectiveness and skepticism around topical dutasteride for hair loss, with mentions of combining it with other treatments like minoxidil and oral medications. Some users doubt its efficacy due to lack of independent studies and potential conflicts of interest.

community Hormonal panel after 1 year of treatment - DHT levels doubled!!

in Finasteride/Dutasteride 7 upvotes 11 months ago

A 27-year-old man shared his hormonal panel results after one year of taking finasteride 1mg/day for hair loss, showing his DHT levels nearly doubled. He reported stabilized hair loss with mild side effects that resolved, and he is considering a hair transplant but is concerned about the increased DHT levels and potential treatment options.

community Started my treatment 2 months ago, wanted to share some progress pictures and regime. What do you guys think?

in Progress Pictures 44 upvotes 1 year ago

PreparationAbject378 has been following a comprehensive regime of medications and lifestyle changes for the past two months to help with hair loss, including Dut, Minoxidil, Finasteride, RU58841, Keto shampoo, Derma pen, a running routine, diet modifications and supplements.

community What are your thoughts on Redensyl? 85% success rate?!

in Treatment 6 upvotes 2 years ago

Hair loss discussion mentions Redensyl with 85% success rate and visible regrowth. Users skeptical, prefer Minoxidil, Finasteride, and RU58841.

community 10 month update! Fin/min/dermaroller/niz

438 upvotes 5 years ago

A 10 month update on the effectiveness of a hair loss treatment regimen involving minoxidil, finasteride, dermarolling and nizoral. Questions were asked about using minoxidil alone, dermaroller length, age, and when results were seen.

community 11 weeks on topical minox/finasteride/microneedle/LLT. Are these good results?

in Is this regrowth? 70 upvotes 1 month ago

The user has been using topical minoxidil, finasteride, microneedling, and laser light therapy for 11 weeks to address hair thinning. They report difficulty applying the treatment due to increased hair thickness and are unsure if the results are significant.