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      community Coegin Pharma to release Follicopeptide (FOL005) by Q2 2025

      in Treatment  117 upvotes 2 months ago
      Follicopeptide (FOL005) by Coegin Pharma will launch as a cosmetic hair growth treatment by Q2 2025, showing similar efficacy to finasteride. Users discuss the benefits and skepticism of releasing hair loss treatments as cosmetics rather than drugs.
      FCE 28260: A Forgotten 5α-Reductase Inhibitor

      community FCE 28260: A Forgotten 5α-Reductase Inhibitor

      in Research  330 upvotes 3 months ago
      FCE 28260 (PNU 156765), an under-explored 5α-reductase inhibitor, showcases promising results in research by Giudici et al., outperforming well-known treatments like Finasteride in reducing the conversion of testosterone to DHT. Its superior efficacy, demonstrated through lower IC50 values in both natural and human recombinant enzyme studies, suggests it could offer more effective management of DHT-related conditions. Additionally, its lower molecular weight hints at better potential for topical application, potentially offering advantages in treating conditions such as androgenic alopecia. Despite its potential, it has not advanced in development, possibly due to financial limitations, leaving its therapeutic prospects and side effect profile largely unexplored.

      community Hair loss treatment tier list by Dr Oscar Muñoz

      in Treatment  920 upvotes 3 months ago
      Dr. Oscar Muñoz's hair loss treatment tier list suggests oral minoxidil and finasteride are highly effective, while topical treatments like RU58841 and microneedling are less effective. Users discuss the effectiveness of various treatments, with some favoring oral options for their practicality and higher response rates.

      community Am discouraged, tried just about everything....

      in Chat  2 upvotes 3 months ago
      The user has tried finasteride, minoxidil, dutasteride, microneedling, retinol, topical finasteride, and ketoconazole for hair loss but continues to experience hair recession. They are considering adding oral minoxidil or RU58841 and are unsure about the next steps.

      community Proof that finasteride messes with neurosteroids

      in Research/Science  230 upvotes 4 months ago
      Finasteride can impact neurosteroids, potentially causing depression and other side effects in some users. Despite these concerns, many continue using it for hair loss, with some switching to topical applications to mitigate side effects.

      community At least my hair is getting thicker. 1.25 oral min

      in Is this regrowth?  117 upvotes 6 months ago
      The user reports hair thickening after 2 months on 1.25mg oral minoxidil and 1mg oral finasteride, having previously used topical minoxidil with no improvement. Other users suggest taking consistent progress photos and share their own experiences with similar treatments.

      community Oral minoxidil is not an option anymore

      in Minoxidil  42 upvotes 7 months ago
      A user can't refill their oral minoxidil prescription due to it being out of stock and is seeking alternative hair loss treatments. Suggestions include finding it at another pharmacy, ordering online, using topical minoxidil orally, and considering finasteride or dutasteride.

      community Approximation of Scalp DHT Suppression Between 0.05 mg to 2.5 mg

      in Research/Science  63 upvotes 9 months ago
      The conversation discusses the effectiveness of various doses of Dutasteride in reducing scalp DHT and its impact on hair count. Users shared personal experiences with hair loss treatments, including Dutasteride, Finasteride, and Minoxidil, with one reporting significant hair loss reduction using a combination of oral Dutasteride and topical Minoxidil and Finasteride.

      community 18M 10 months on anti-androgens and oral min

      in Progress Pictures  50 upvotes 1 year ago
      An 18-year-old male used anti-androgens and oral Minoxidil for 10 months to treat hair loss. He initially used 1mg Finasteride and 5% topical Minoxidil for 5 months, then switched to Dutasteride for 4.5 months and inconsistently used 5mg oral Minoxidil for 2 months due to availability issues.

      community Are there ever going to be any oral DHT blocking treatments in the future?

      in Product  6 upvotes 1 year ago
      The discussion revolves around the need for future oral DHT blockers for hair loss treatment that don't have the side effects of current options like Finasteride and Dutasteride. One user suggests that the future of hair loss treatment will likely be topical anti-androgens, as they can target hair follicles without affecting the entire system.

      community 11 month progress on a cocktail regiment

      in Progress Pictures  439 upvotes 1 year ago
      The user "Dismal_Library_2264" shared their 11-month progress on a hair loss treatment regimen. They used dutasteride, topical minoxidil, dermarolling, a hair serum, and specific shampoos. They experienced some side effects but were overall satisfied with the results.

      community (M24) ~5 years progress on Fin & Min. AMA

      in Progress Pictures  1693 upvotes 1 year ago
      The user "LandB4TimeIn3D" shared their hair loss progress using finasteride (Fin) and minoxidil (Min). They experienced shedding for the first few years but saw significant regrowth after about 2-3 years. They also mentioned using topical liquid minoxidil twice a day.

      community Starting over at 40 with microneedling

      in Progress Pictures  9 upvotes 1 year ago
      A person had success with micro-needling for hair growth but stopped and noticed hairline recession. They plan to restart treatment at age 40, using micro-needling, oral minoxidil, finasteride, a laser cap, topical minoxidil with tretinoin, collagen, and other supplements.

      community 1.5 year progress update 1mg Fin and 5% minoxidil

      in Progress Pictures  343 upvotes 1 year ago
      A user shared a 1.5-year hair loss treatment progress using 1mg Finasteride and 5% Minoxidil, planning to switch to oral Minoxidil and considering adding RU58841. They saw gradual improvement, suspecting Finasteride as the main contributor since they might not respond to topical Minoxidil.

      community Love me some Dutasteride. 40 years old. March to now

      in Progress Pictures  753 upvotes 1 year ago
      The conclusion of this conversation about hair loss is that the user, "mynameisbogus," has been using Dutasteride, oral minoxidil, topical minoxidil, RU58841, dermarolling, scalp massaging, and keto shampoo to treat their hair loss. They have not experienced any side effects and have seen positive results.

      community Why I Will be Accepting Baldness

      in Chat  204 upvotes 1 year ago
      User decides to accept baldness due to mental health issues with finasteride. Others suggest considering hair systems, topical finasteride, or RU58841 as alternatives.

      community 2 months on minoxidil 5% GOOD RESULTS?

      in Progress Pictures 2 years ago
      Asteride into your routine In this conversation, the user Icy-Indication267 was asking when they should start finasteride to treat their hair loss, which had responded well to minoxidil after two months. Other users shared advice on incorporating micro-needling and topical finasteride into their routine for optimal results.

      community Around 11 months of progress on hairloss medication.

      in Finasteride/Dutasteride  344 upvotes 2 years ago
      Royal_Woodpecker0007: Hahaha . No i am not naked . This conversation is about Royal_Woodpecker0007's 11-month progress on hair loss medications, including topical finasteride and minoxidil, as well as oral finasteride and keto 1% shampoo. The treatments have shown positive results, reducing his hairfall from 200 hairs per day to 40-50, and thickening his hairline. He plans to wait another year before considering a transplant.

      community Oral Minoxidil Users In A Nutshell

      in Satire  1210 upvotes 2 years ago
      This conversation is about hair loss treatments, specifically oral minoxidil and finasteride. Users discussed the potential side effects of using these drugs, as well as their experiences with them.