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GlossaryTNF inhibitors

medications that block inflammation-causing proteins in autoimmune diseases

TNF inhibitors, also known as Tumor Necrosis Factor inhibitors or TNF blockers, are medications that reduce inflammation by blocking the activity of TNF-alpha, a substance in the body that causes inflammation and can lead to immune system diseases. They are commonly used to treat autoimmune conditions such as rheumatoid arthritis, psoriasis, and inflammatory bowel disease by preventing the immune system from attacking healthy tissues.

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community The MPB itch aka DHT itch is very real.

in Chat 9 upvotes 1 year ago

Hair loss itch is caused by DHT attacking follicles and stimulating nerves. Finasteride users who respond well don't experience this itch.

community UPDATE: The theory that explains everything. Please help me make this big!

in Research/Science 449 upvotes 3 years ago

Hair loss theory involves 3alpha-hydroxysteroid reductase (3AHD) converting DHT to androstenol. Discussion explores potential treatments and encourages more research.

community What is the real impact of dutasteride on neurosteroids? A little review of 2 scientific datas

in Research/Science 21 upvotes 4 months ago

Dutasteride at 0.5 mg/day does not significantly alter allopregnanolone levels, but higher doses (2.5 mg/day) do. Dutasteride may also have anti-neuroinflammatory effects, but the impact on neurosteroids is still debated.

community Diffuse hair loss and scalp biopsies

in Research 692 upvotes 3 months ago

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

community NMN Promotes Cell Proliferation and Hair Growth by Reducing Oxidative Stress

in Research/Science 14 upvotes 5 months ago

NMN shows promise in promoting hair growth by reducing oxidative stress and weakening androgens. It may be a beneficial addition to hair loss treatments like Minoxidil and Finasteride.

community 3 months. Dut, Min, Keto, Vitamin D, exercise

in Progress Pictures 353 upvotes 2 years ago

A user's experience using dutasteride, minoxidil, ketoconazole, vitamin D, scalp massage, exercise, and avoiding vaping and 2-in-1 shampoo/conditioner to treat hair loss; they also discussed the side effects of finasteride.

community Topical Finasteride update by H&W

in Finasteride 28 upvotes 7 years ago

The conversation discusses using topical finasteride for hair loss, with concerns about its safety around family members, especially pregnant women and infants. One user plans to try topical finasteride due to side effects from the pill.