Dutasteride at 0.5 mg/day does not significantly alter allopregnanolone levels, but higher doses (2.5 mg/day) do. Dutasteride may also have anti-neuroinflammatory effects, but the impact on neurosteroids is still debated.
NMN shows promise in promoting hair growth by reducing oxidative stress and weakening androgens. It may be a beneficial addition to hair loss treatments like Minoxidil and Finasteride.
The conversation discusses using topical finasteride for hair loss, with concerns about its safety around family members, especially pregnant women and infants. One user plans to try topical finasteride due to side effects from the pill.
Hair loss theory involves 3alpha-hydroxysteroid reductase (3AHD) converting DHT to androstenol. Discussion explores potential treatments and encourages more research.
A user expressed frustration with hair loss treatments, including finasteride, minoxidil with micro-needling, and RU58841, which all failed to stop hair thinning and miniaturization. Suggestions from others included accepting baldness, considering hair systems, and continuing prescribed antidepressants for depression.
A 20-year-old who started balding in 2020 and has been using a treatment routine for 4 months that includes daily Minoxidil (1.5ml), Finasteride three times a week, and a derma roller twice a week, along with a 2-month course of vitamin supplements. The treatment has significantly improved their hair loss, boosting their confidence.
The user experienced significant hair regrowth using Propecia (finasteride) 1 mg and topical minoxidil twice a day over 16 months, despite initial shedding. The user no longer needs a hair transplant and reports no side effects from the treatment.
Hair loss treatments mentioned: finasteride, dutasteride, and hair transplant. Misunderstandings in conversation involve wordplay on "bill," "check," and "to pay" sounding like names and phrases.
The conversation discusses hair loss treatments, specifically Minoxidil, finasteride, and RU58841. Users are asked to share their experiences with Pyri/Koshine.
A user shared their 10-month hair loss progress using Propecia, oral minoxidil, and topical minoxidil. The results were highly praised, with requests for more details on dosages and routine.
The conversation is about the double standard in the hair loss community regarding shedding when using different treatments. The conclusion is that shedding is considered normal when starting finasteride or minoxidil, but not when starting dutasteride, despite the fact that dutasteride is more effective at reducing DHT.
A user in their mid-30s experienced unexpected hairline regrowth after starting a new supplement stack, despite being on a regimen of finasteride, minoxidil, and Nizoral for over four years. The new supplements include Tongkat Ali, Fadogia Agrestis, Panax Red Ginseng, Vitamin B1, Vitamin D3, Zinc Picolinate, Magnesium Glycinate, Maca, and L-Citrulline.
Hair loss treatment with 3 months Minoxidil and Microneedling, 1 month 0.25 finasteride daily. User reports progress, others discuss effectiveness of Microneedling.
A young man in his mid-20s started using finasteride and biotin for hair thinning and has seen less hair loss after three months. Others shared their positive experiences with minoxidil and finasteride, discussed potential side effects, and encouraged early treatment for hair loss.
Dutasteride's half-life varies with dosage, and lower doses can be effective with fewer side effects compared to finasteride. Some users report different side effects with dutasteride and finasteride, and extreme dosages of dutasteride are unnecessary and potentially harmful.
A user shared a nine-month hair regrowth progress using 5mg oral Minoxidil and 1.25mg oral Finasteride daily, with noticeable improvement and no side effects, despite a high-protein diet, occasional smoking, and regular exercise. They also mentioned using keto shampoo and having naturally increased body hair by about 10%.
A 24-year-old male has been using finasteride and minoxidil for a year with little hope. Suggestions include adding dutasteride, oral minoxidil, micro needling, and considering a hair transplant.
Person shared 7-month progress of hair growth using finasteride, minoxidil, and nizoral shampoo. Happy with results, experienced minimal shedding, and applies double dose of minoxidil at night.
Actor Paul Mescal, who has a receding hairline, and how it affects his success in the entertainment industry. People discussed how styling can help disguise hair loss, and that hair loss doesn't necessarily mean one's appearance is immediately ruined. Treatments such as Minoxidil and Finasteride were mentioned to combat hair loss.
A user's hairline recovery after severe hair loss, which was treated with Dutasteride and Minoxidil; other users offered their opinions on the severity of the hair loss.
Hair loss treatments, specifically 5AR inhibitors, can impact neurosteroids and sexual health. The effects of topical fin/dut on tissue-specific DHT levels are unclear.
The user "Specialist_Let_9455" shared their positive results after 6 months of using finasteride for hair loss. They plan to continue using finasteride for one year before considering other treatments.
A user shared their 10.5-month progress using oral finasteride, topical minoxidil, a derma roller, biotin, and Omega 3, despite losing over 150 hairs daily. They also mentioned starting "bald showers" after leg workouts for the last two months.
A user shared their 9-month progress using Propecia and minoxidil for hair loss, noting significant daily shedding. Others suggested potential vitamin/mineral deficiencies and offered encouragement.
User reports two-month progress using Min, dermarolling, and Hair Savior Oil. Others suggest adding Ketoconazole for dandruff and hair growth, and continuing Min use to maintain results.
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This conversation is about a user's progress while using minoxidil and finasteride to treat hair loss, with emphasis on taking oral finasteride at night before bed for optimal results. They also discuss the brand of medication being used (Morr F 5%) and the importance of taking a generic version of the same drug.
The conversation discusses the complexity of hair loss causes, suggesting that DHT sensitivity alone doesn't fully explain it. Treatments mentioned include finasteride and dutasteride.