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GlossaryArtificial Skin (Engineered Skin Substitutes)

laboratory-created substitute mimicking natural human skin functions

Artificial skin, also known as synthetic skin or bioengineered skin, is a laboratory-created substitute designed to mimic the properties and functions of natural human skin. It is often used in medical treatments for burn victims, chronic wounds, and other skin injuries, providing a temporary or permanent covering that promotes healing and reduces the risk of infection. This engineered tissue can be composed of various materials, including collagen, silicone, and biodegradable polymers, and may incorporate living cells to enhance integration with the patient's own tissue.

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community Verteporfin update - donor hair regeneration human trial

Synizs in Research/Science 22 upvotes 2 years ago

A human trial of verteporfin, a potential treatment for hair loss, with some users noting potential improvements in scarring and overall healing compared to control areas.

community So we have 20k dollars human like machines available but no new effective treatment for hairloss since finasteride :)

Busy-Order-9093 in Chat 237 upvotes 3 months ago

There have been no new effective hair loss treatments since finasteride, despite technological advancements. Current treatments include finasteride, minoxidil, and RU58841, with ongoing challenges and potential future solutions in research.

Compressed part of research of theory of androgenic/anabolitic balance. AGA h-responders analytic. Theory of physio-metabolitic method of anti AGA treatment

community Compressed part of research of theory of androgenic/anabolitic balance. AGA h-responders analytic. Theory of physio-metabolitic method of anti AGA treatment

MagicBold in Research 823 upvotes 3 months ago

The treatment for androgenetic alopecia involves using finasteride and minoxidil with intense exercise and cold exposure to boost metabolism and reduce androgenic effects, potentially leading to hair regrowth. This approach may activate biological pathways for improved hair and overall health.

community Can Minoxidil be Aging My Skin?

ScoutisaSniper in Minoxidil 6 upvotes 3 years ago

Minoxidil may cause skin aging effects like wrinkles and dark circles, but evidence is mixed. Alternatives like dermarolling and retinol are suggested.

community Unofficial Dermapen/Roller Guide

X211499Reddit in Treatment 251 upvotes 6 years ago

Treatments for hair loss, including microneedling (dermarolling and dermapen) and the use of minoxidil, finasteride, and RU58841. It provides detailed information about cost and usage of the various treatments, as well as potential side effects.

community Binding affinity of pyrilutamide!

alexffy66433 in Update 171 upvotes 2 years ago

Pyrilutamide, a nonsteroidal antiandrogen drug under development for the potential treatment of androgenic alopecia. The conversation discusses its binding affinity to the androgen receptor and the timeline for possible availability after trials are completed in the United States and China.

community Solving Hair Loss with Research at MIT

ekkolapto1 in Research/Science 594 upvotes 3 months ago

Hair loss treatments like minoxidil, finasteride, TDM-105795, and PP405. MIT is hosting a hackathon to find innovative hair loss solutions.

community UPDATE: The theory that explains everything. Please help me make this big!

joaopassos4444 in Research/Science 448 upvotes 3 years ago

Hair loss theory involves 3alpha-hydroxysteroid reductase (3AHD) converting DHT to androstenol. Discussion explores potential treatments and encourages more research.

community Why is everyone not directly advised Dutasteride?

Jamelco123 in Finasteride/Dutasteride 169 upvotes 4 months ago

Dutasteride is less commonly prescribed for hair loss because it is not FDA-approved for this purpose, unlike finasteride, which is more accessible and preferred due to fewer side effects. Dutasteride may be more effective in reducing DHT but has a longer half-life and potentially more significant side effects.

community Finasteride won’t make all your problems go away

idhke in Finasteride/Dutasteride 323 upvotes 1 year ago

A user shared that while finasteride improved their hair, it didn't solve all their insecurities, suggesting that self-acceptance is key. Others in the conversation expressed varying opinions, with some feeling that finasteride significantly boosted their confidence and quality of life, while others acknowledged it as a solution to hair loss but not a cure-all for other personal issues.

community Hair Cloning Nears Reality as Baldness Cure - Nov 4, 2004

Youwillbetossed 62 upvotes 5 years ago

Hair cloning was predicted to be a baldness cure within 3-4 years in 2004, but it has not materialized. Users express frustration and skepticism about the delay.

community Breezula phase 3 results said to be released next month

Fast_Midnight_6666 in Product 26 upvotes 1 month ago

Breezula's phase 3 results are expected soon, with discussions on the effectiveness of androgen receptor antagonists like spironolactone and the potential of GT20029. Users express skepticism about new treatments and discuss the complexities of male pattern baldness, often relying on finasteride despite its side effects.

community dht becoming active since the scalp is tight en cause inflammation

DashcubeBM in Research/Science 6 upvotes 2 years ago

User discusses tight scalp causing hair loss and suggests treatments like scalp massages, PRP, saw palmetto, and eucapil. They share their experience with saw palmetto and eucapil and consider adding PRP and scalp massages for better results.

community Hello everyone! I just wanted to show you guys my hair transplant result so far. I actually really liked it. And I recommend a hair transplant for everyone who suffering from baldness. I'm 37 and I feel regret that why I didn't have a hair transplant till that time.

SolutionDifficult127 in Treatment 611 upvotes 3 years ago

A user's successful hair transplant result, and other users recommending finasteride to maintain it.

community 15 months on the Big 3! My journey so far…

No-Organization-2585 in Progress Pictures 162 upvotes 2 years ago

A user's progress after 15 months of using the "Big 3" treatments for hair loss (finasteride, minoxidil and micro needling) as well as Nizerol 2%. The post encourages others to seek out available information on hair loss treatment and reassures them that if it doesn't work, it is only hair.

community How promising is th RCH-01/Replicel treatment? Is there any new info that suggests it will be as successful as it claims? What other promising treatments are close?

ickiestofthesticki in Technology 14 upvotes 5 years ago

The conversation is about the potential of the RCH-01/Replicel hair loss treatment and its lack of updates since 2013, with the user expressing hope for its success and considering using Minoxidil, finasteride, and dermarolling in the meantime. Other treatments mentioned as promising are Breezula and Tsuji.

community Dutasteride half life - conflicting information

JonnyKilledTheBatman in Finasteride/Dutasteride 10 upvotes 11 months ago

The half-life of Dutasteride is commonly stated as around 5 weeks, but some sources suggest it is 170 hours for men aged 20–49, with further information indicating it varies from 3 days to 5 weeks depending on the dose. The user is seeking clarity on these conflicting figures.

community [HELP!] TOPICAL FINASTERIDE BLOOD TEST DONE! [0.025% vs 0.015%]

tryingbro in Finasteride/Dutasteride 7 upvotes 1 year ago

User experienced good results with topical finasteride, noting reduced DHT and increased testosterone. They plan to revert to a lower dosage after observing slight libido reduction.

community Dutasteride takes 1-3 months to work in the scalp. Not weeks. Be careful.

noeyys in Finasteride/Dutasteride 41 upvotes 5 months ago

Dutasteride takes 1-3 months to affect scalp DHT levels, not just a week. The prostate absorbs Dutasteride faster than the scalp due to different vascular networks and enzyme densities.

community Update: 16 months deep - big 3

Interesting-Art-2447 in Progress Pictures 407 upvotes 1 year ago

The user has seen positive results after 16 months of using topical Finasteride/Minoxidil, microneedling weekly, and Tretinoin for hair loss. There are no reported side effects, and the user advises that the effectiveness of microneedling depends on the pressure applied.

community A systematic bro-science review of DHT, 5AR, neurosteroids, sexual health and 5AR inhibitors

rhguven in Research/Science 37 upvotes 2 years ago

Hair loss treatments, specifically 5AR inhibitors, can impact neurosteroids and sexual health. The effects of topical fin/dut on tissue-specific DHT levels are unclear.

community How Does Exosome Therapy Work for Hair Loss?

healthyhair01 in Research/Science 5 upvotes 1 year ago

Exosome hair therapy involves injecting stem cell-derived exosomes into the scalp to boost hair follicle regeneration and repair. Exosomes, which are not stem cells but products of them, contain bioactive chemicals and specific growth factors that promote new blood vessel formation, increase cell proliferation, reduce inflammation, and improve tissue repair, all crucial for hair health.

community Pyrilutamide update number 2 - 2 week use

ljammm in Update 174 upvotes 2 years ago

An update on the use of Pyrilutamide, a new drug for hair loss, which has resulted in no shedding or testicle ache; other users have questioned the science behind this and shared their own experiences with Finasteride, Minoxidil, and microneedling.

community Just got a dermastamp, and it is FAR superior to a roller. I’ll never go back.

72012122014 in Microneedling 101 upvotes 11 months ago

A user switched from a 1.5 mm derma roller to an adjustable dermastamp for microneedling to treat hair loss and found it less painful and more effective. Some users prefer different depths and tools like the Dr.Pen for microneedling, while others debate the necessity of depth and tool type.

community Sharing my (relatively short) Success Story

paulsac11 in Progress Pictures 77 upvotes 1 year ago

A user named "paulsac11" shares their success story of treating hair loss. They started with topical minoxidil, then switched to oral minoxidil and dutasteride. They also used a shampoo and conditioner from Keeps. After eight months of treatment, they have seen significant improvement in their hairline.

community Molecular mechanisms triggered by Micronedlling -- Intersting Publication to better understand Dermarolling

Scalperrr 25 upvotes 6 years ago

This post and conversation are about the molecular mechanisms triggered by microneedling, specifically its effects on inflammation, tissue remodeling, epithelial proliferation, differentiation, and collagen synthesis. The discussion highlights the potential benefits of microneedling for hair loss treatment.

community Verteporfin Update #2: Day 1 through Month 1 | Dr Blake Bloxham | Feller & Bloxham Medical | NY, NYC

Previous_Advertising in Research/Science 29 upvotes 1 year ago

The conversation discusses the use of Verteporfin in hair loss treatment. It suggests that Verteporfin could potentially regenerate hair follicles instead of forming scars, providing an unlimited donor supply for hair transplants.

community What’s the science behind 1mg Finasteride 3 X a week being as effective as daily?

8-bit-hero in Finasteride/Dutasteride 19 upvotes 1 year ago

The efficacy of taking 1mg finasteride three times a week instead of daily for hair loss, with some users arguing that it is just as effective because finasteride has a long half-life in the scalp tissue and lower doses have been shown to be effective. Other users suggest experimenting with various treatments such as minoxidil and finasteride to achieve best results.

community 8 months on finasteride, I will continue with only fin for one full year until I hop on anything else. 24M, 1.25mg daily. Every pic is taken at the start of every month, the first one is when i started the medication.

Specialist_Let_9455 in Progress Pictures 588 upvotes 1 year ago

A user's 8-month progress on finasteride for hair loss treatment, with plans to continue for a full year. The user experienced initial shedding and scalp itch, which subsided, leading to hair growth. Other users discussed the necessity of continuous treatment to maintain results.

community New and Interesting HairLoss Studies/Papers/Reviews

TerpsandCaicos in Treatment 41 upvotes 5 years ago

Hair loss treatments discussed include Dutasteride with Ketoconazole, tissue engineering strategies, and androgenetic alopecia therapies. Massage doubles follicular retention, improving treatment effectiveness.