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    GlossaryTransforming Growth Factor Beta 1 (TGFB1)

    protein regulating cell growth, differentiation, and immune responses

    Transforming Growth Factor Beta 1 (TGF-β1) is a protein that plays a crucial role in regulating cell growth, differentiation, and immune responses. It is involved in various biological processes, including wound healing and the development of fibrosis, and can influence hair growth by affecting the hair follicle cycle.

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      community Group Buy for MR antagonist finerenone

      in Product  11 upvotes 1 year ago
      User discusses group buy for finerenone, a third-gen mineralocorticoid antagonist for hair loss treatment. Finerenone inhibits TGFb, NOX, and ROS, and improves renal and cardiac function; topical dose should be no more than 10mg per day.

      community Taurine supplements work for hair growth?

      in Product  8 upvotes 6 months ago
      The conversation discusses taurine supplements for hair growth, highlighting their potential to reduce DHT and improve hair health. A user comments that people often try alternatives to finasteride.

      community Hairloss - what hormones to check?

      in Finasteride/Dutasteride  10 upvotes 11 months ago
      The user is concerned about hair loss despite using oral finasteride, oral minoxidil, and topical minoxidil. They are seeking advice on additional blood tests to identify potential causes.

      community HLT Megathread on HMI-115 (key takeaways in comments)

      in Research/Science  38 upvotes 1 year ago
      HMI-115, a newly discovered hair loss treatment that could potentially be effective for those with diffuse thinning and telogen effluvium. It is based on prolactin receptor antagonist signaling and has already undergone Phase I trials in women, with potential commercialization by 2027.

      community Opinions on Scalp fibrosis and DHT?

      in Research/Science  9 upvotes 2 years ago
      The conversation discusses the theory that scalp fibrosis contributes to male pattern baldness (MPB) by increasing DHT concentration, and mentions treatments like Minoxidil. The user seeks opinions on the theory and the effectiveness of scalp massages.

      community Hair loss causes are still a myth.

      in Chat  16 upvotes 3 years ago
      The conversation discusses the complexity of hair loss causes, suggesting that DHT sensitivity alone doesn't fully explain it. Treatments mentioned include finasteride and dutasteride.