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GlossaryTransglutaminase 3 (TGase 3)

enzyme crucial for skin and hair protein cross-linking

Transglutaminase 3 (TGM3) is an enzyme that plays a crucial role in the formation and maintenance of the outer layer of the skin and hair follicles. It helps in the cross-linking of proteins, which strengthens the structural integrity of these tissues. Deficiencies or malfunctions in TGM3 can lead to skin disorders and hair loss conditions.

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community Reminder that Kintors Pyrilutamide results will be out this month

in Treatment 178 upvotes 3 years ago

Kintor's Pyrilutamide results for hair loss treatment will be released soon. The treatment may replace current treatments like finasteride and minoxidil without systemic side effects.

community The Finasteride Shed is real.

in Finasteride/Dutasteride 159 upvotes 2 months ago

Increasing finasteride dosage can cause significant hair shedding initially. Users suggest adding minoxidil or switching to dutasteride for better results.

community Wasn't Breezula supposed to post some results soon?

in Question 16 upvotes 5 years ago

The conversation is about expecting results from Breezula, a hair loss treatment, with no new information released as of April 1st. Some joked it's just onion juice, while another comment suggested a conspiracy to cause baldness.

community Finally progress! - 4 month on 1.25mg FIN (daily) + MIN + Dermarolling

in Progress Pictures 199 upvotes 10 months ago

The conversation discusses a user's progress after 4 months of using 1.25mg finasteride daily, minoxidil, and dermarolling to treat hair thinning, particularly on the sides and crown. The user believes finasteride made the most difference, and they share tips on managing hair loss and tracking progress.

community New potential hair loss treatment (news release)

in Treatment 186 upvotes 4 years ago

New potential hair loss treatment uses molecules from hairy moles to stimulate follicle growth. Topical solution requires less frequent application, like Botox injections a few times per year.

community The worst thing about hair loss? Rant here!

in Chat 125 upvotes 5 months ago

Hair loss deeply affects self-esteem and mental health. Treatments mentioned include hair transplants, Minoxidil, Finasteride, and RU58841.

community Is it normal to lose body hair on finasteride?

in Research/Science 11 upvotes 8 months ago

Finasteride can cause body hair loss, which is normal. It may also be due to disease or nutrient deficiencies.

community My dad 61y/o healed from full bald to full head of hair

in Finasteride/Dutasteride 173 upvotes 10 months ago

A user's 61-year-old father regained a full head of hair after four years on dutasteride for his prostate and five months of weight loss and exercise. The user decided to switch from finasteride to dutasteride and continue exercising, inspired by his father's results.

community Finasteride vs Dutasteride, some helpfully info I put together as a physician

in Finasteride/Dutasteride 18 upvotes 10 months ago

The conversation discusses the pros and cons of dutasteride for male pattern baldness, with a focus on its long half-life. The user, a physician, also mentions that switching from finasteride to dutasteride can cause temporary hair loss until dutasteride reaches effective levels or accelerates the hair cycle.

community Holy shit. Verteporfin may actually be the cure

in Research/Science 1014 upvotes 1 year ago

The post and conversation discuss Verteporfin's potential as a hair loss treatment. It's shown promise in regrowing hair after transplants and might be effective with microneedling.

community The crazy thing with diffuse thinning is one day you think you have no hair loss, and another day you think you have no hair

in Chat 398 upvotes 1 year ago

The post and conversation discuss the unpredictable nature of diffuse thinning, a type of hair loss. Users share personal experiences, with some mentioning treatments like oral finasteride and toppik, and the need for patience with these treatments.

community Trying to understand finasteride side effects and post finasteride syndrome

in Finasteride/Dutasteride 74 upvotes 4 years ago

The conversation discusses the side effects of finasteride, including low libido and erectile dysfunction, and the possibility of these effects being permanent, known as post-finasteride syndrome (PFS). Some users report personal experiences with PFS and debate whether the condition is real, with varying opinions on the reversibility of side effects and the role of individual biology.

community 16 months or so. Back from the dead. Age 41

in Progress Pictures 555 upvotes 5 months ago

A user shared their 16-month hair regrowth progress using oral and topical minoxidil, dutasteride, derma rolling, and occasional keto shampoo. The conversation includes positive reactions and jokes about their impressive results.

community Is there any new drug that looks promising ?

in Research/Science 25 upvotes 8 months ago

The conversation discusses GT20029, a drug in Phase II trials that targets androgen receptors with minimal systemic effects, and TDM-105795, a growth stimulant with a different mechanism than minoxidil that may revive papilla stem cells. Both are potential new treatments for hair loss.

community New Treatments, and a Huge Group Buy with Lots of Research

in Research/Science 109 upvotes 1 year ago

A user is organizing a group buy for various compounds aimed at reversing hair loss and gray hair, and improving brain health and fat loss. The user has developed a treatment plan based on extensive research and is inviting others to participate, with the option to choose only the compounds they need.

community Shrooms have done more for my hair loss than all of my hair supplements/medications combined.

in Satire 408 upvotes 1 year ago

Finding acceptance of hair loss through psychedelics, and the potential benefits of shrooms. Discussions include sharing experiences with minoxidil, finasteride, nutrafol, laser therapy, micro needling, as well as mental health concerns such as depression, suicidal thoughts, and self-esteem.

community Bald groom beaten over fake hair.

in Satire 881 upvotes 1 year ago

A bald groom was beaten by the family of the bride for wearing a wig. The conversation discusses the cultural stigma around baldness in India and the consequences of deception in arranged marriages.

community Listen to anyone besides your Mom while fighting hair-loss

in Satire 464 upvotes 4 years ago

Hair loss treatments, with people sharing their experiences of trying to get help from family members and how genetics can affect the severity of hair loss. Treatments mentioned include finasteride, minoxidil, RU58841, scalp massage, whey protein and bleaching.

community I rather have receding temples than diffused thinning all over

in Chat 102 upvotes 3 years ago

User with diffused thinning hair prefers receding temples, as hair transplant could fix it. Finasteride and minoxidil suggested to improve hair density.

community Has anyone had success Dermarolling without Min?

in Microneedling 12 upvotes 3 years ago

The conversation is about the effectiveness of Dermarolling for hair loss without using Minoxidil. Some people consider using peppermint oil as an alternative.