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Glossary Tet3

enzyme involved in DNA demethylation affecting gene expression

Tet3 is an enzyme that plays a crucial role in DNA demethylation, a process that can activate or deactivate genes. It is part of the TET (Ten-Eleven Translocation) family of enzymes, which are important for regulating gene expression and maintaining cellular functions. In the context of hair biology, Tet3 could influence the expression of genes involved in hair growth and development.

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community mallia therapeutics 8T3 scd83 molecule for ffa/lpp mainly and aga

in Technology 9 upvotes 7 months ago

A user applied the 8T3 product for hair loss, targeting LPP and AGA, and plans to update on its effectiveness. The product uses a saline buffered phosphate vehicle, suitable for those intolerant to ethanolic vehicles.

community Rejux-3x - the copper peptide combo that tressless overlooks.

1 upvotes 5 months ago

Rejuv-3X, a topical blend with GHK-Cu, AHK-Cu, and JXL-089, is used for hair loss, offering a targeted option without finasteride's side effects. The user plans to combine it with microneedling for enhanced results.

community Expectations control for SCUBE3

20 upvotes 2 years ago

SCUBE3, a protein linked to hair growth in moles, was discovered over 25 years ago and is being developed by Amplifica for potential hair loss treatment. Concerns exist about SCUBE3's association with cancer, as it is a protein that promotes cell growth, which could potentially trigger cancer development if used for hair growth therapy.

community Can somebody tell my why Scube3 is not going to work?

7 upvotes 2 years ago

The conversation discusses concerns about Scube3's effectiveness and potential cancer link. It questions whether Scube3 can regrow hair and how well it works according to researchers.

community SUBE3 for sale in the gray market?

5 upvotes 1 year ago

SCUBE3 is available online but poses risks like tumor promotion and high costs. Users advise against using it due to health concerns and inefficacy as a standalone treatment.

community Twist-1 vs Scube-3. Is it worth pursuing both?

15 upvotes 4 years ago

Twist-1 is being explored as a promising early-stage hair loss treatment, while Scube-3's effect on Twist-1 in breast cancer cells raises concerns about its use for hair loss. The conversation discusses the potential differences in protein effects across various cell types.

community Any success at regrowth without the big3?

5 upvotes 6 years ago

Some users report minor hair regrowth using natural treatments like peppermint oil, dermarolling, and lifestyle changes, but results are limited. Others find more success with treatments like minoxidil, finasteride, and nizoral, while some remain skeptical of natural methods.

community SCUBE3 and GT20029 could be the closet thing to a cure: Hair Follicle Regeneration and Protection Against DHT

14 upvotes 3 years ago

SCUBE3 and GT20029 are potential treatments for hair loss, with SCUBE3 stimulating hair growth and GT20029 protecting against DHT. A combined approach using SCUBE3, finasteride or dutasteride, and later GT20029 could provide a comprehensive treatment for androgenetic alopecia.

community DUT 3 times a week is the holy grail sweet spot, better than FIN every day.

6 upvotes 4 years ago

User "logart89" claims DUT 3 times a week is better than daily FIN for hair loss. Their routine includes DUT, topical DUT, stemoxydine and alfatradiol mix, 5% minoxidil with tretinoin, and weekly derma stamping.

community 3 months treatment (m23) is there any progress?

29 upvotes 5 months ago

The user reported progress in hair regrowth after 3 months using finasteride, biotin, and minoxidil, with no sexual side effects. Most responses noted significant improvement, encouraging continued use for full results.

community What are we thinking about this SCUBE3 boys

in Product 7 upvotes 11 months ago

SCUBE3 is a promising new molecule that can restart hair growth by reawakening dormant hair follicles. Users express skepticism about its availability timeline, with some hoping for release by 2026.

community New ingredients - GHK-Cu or Acetyl Tetrapeptide-3?

2 upvotes 7 months ago

GHK-Cu and Acetyl Tetrapeptide-3 are ineffective for hair regrowth according to user experiences. Effective treatments mentioned are finasteride, dutasteride, and minoxidil.

community Japan-led "Third Cell" Discovery: Is this the missing link for full follicle regeneration?

in Technology 132 upvotes 6 months ago

A new "third cell" discovery in Japan could be key to fully regenerating hair follicles, with human trials possibly starting in 2027-2028. AI is expected to accelerate medical discoveries, potentially leading to a hair loss cure within a few years.

community Wrap it up everyone. CB-03-01 is another failed treatment

79 upvotes 1 year ago

CB-03-01 is considered a failed treatment for hair loss, with future hopes pinned on PP-405 and GT-20029, expected by 2030. Alternatives like hair transplants and SMP are discussed, while some users express frustration over the slow progress of treatments like Breezula.

community 3 month results - ready to grow my hair again.

in Progress Pictures 5 upvotes 10 months ago

A user shared their positive 3-month hair regrowth results using a 3-in-1 pill containing finasteride, minoxidil, and biotin, with no side effects. They also started microneedling, Nizoral, and caffeine shampoo to enhance growth.

community The Big 3 Worked for Me - 610 Days

in Progress Pictures 111 upvotes 1 year ago

The user experienced successful hair regrowth over 610 days using Finasteride, Minoxidil, and Nizoral shampoo, with no side effects and improved mood. They encourage patience in the hair growth process.

community Amplifica and AMP-303 clinical phase 1

9 upvotes 2 years ago

Amplifica is testing a compound called AMP-303 for hair loss, but it's not Scube3 or osteopontin. The timing for the results from the clinical trial is unknown.

community When Scube3 even start trial 1?

in Research/Science 12 upvotes 2 years ago

Scube3 trials have not started yet. Treatments discussed include Minoxidil, finasteride, and RU58841.

community Is this regrowth? 3 month progress since mixing treitinoin with minoxidil

in Is this regrowth? 7 upvotes 1 year ago

The user mixed tretinoin with minoxidil and noticed hair regrowth after three months, despite initial dryness. Their regimen includes 0.5mg dutasteride every other day, daily topical minoxidil with 0.025% tretinoin gel, and ketoconazole shampoo twice weekly.

community Proof DHT is not the main cause of hair loss. TRPS1 Gene and Protein might be. PP405 won’t work. AMP-303 might!

153 upvotes 6 months ago

Hair loss may be linked to the TRPS1 gene and protein, not just DHT. Amplifica's AMP-303 targets mesenchymal stem cells and shows promise in treating hair loss, unlike Pelage's PP405.

community PTD-DBM Update: Q&A With Dr. Kang-Yell Choi

15 upvotes 7 years ago

PTD-DBM is being explored for hair regrowth by targeting CXXC5, with clinical trials expected after pre-clinical studies. Users express anticipation and skepticism about its effectiveness.

community 3 month progression w/ BIG 3. Fin/ Min & Keto Shampoo

in Progress Pictures 10 upvotes 1 year ago

The user shares a 3-month hair loss treatment progress using finasteride, minoxidil, and ketoconazole shampoo. They plan to add a dermatologist pen to their routine for the next 3-6 months.

community Anyone tried CB-03-01?does it work ?

in Research/Science 2 upvotes 1 year ago

CB-03-01, also known as Breezula, is being considered as an alternative to DHT blockers for hair loss. Users are discussing its effectiveness, potential regrowth, side effects like scalp irritation, and hormonal impacts.

community Any experiences with Ptd-dbm??

8 upvotes 3 months ago

The user experienced reduced hair loss using an online serum but found it too expensive and is seeking a vendor for ptd-dbm. They are also interested in KY19382 but are unable to find it.

community TH07 by Triple Hair entering phase III trial

6 months ago

A new topical treatment, TH07, combining finasteride, latanoprost, and minoxidil, is entering phase III trials with promising early results. Some users express skepticism, noting the treatment uses existing products.

community TDM-105795 phase 2 results are in!

27 upvotes 2 years ago

TDM-105795 showed promising hair growth results, with higher efficacy than placebo and minimal side effects. It activates dormant hair follicle stem cells and may maintain gains without immediate loss, unlike minoxidil.

community 3 Month Results with Nuclear Stack - 42M

in Progress Pictures 114 upvotes 2 years ago

A user shared 3-month hair regrowth results using a combination of oral Dutasteride, daily Minoxidil, RU58841, micro-needling, Keto shampoo, scalp massages, and supplements. Positive progress was noted, and encouragement to continue was given.

community Pp405 trials question - 2a/2b,

6 upvotes 10 months ago

PP405 trials have completed phase 2a, showing promising results with a 31% stat for hair density increase, and are moving directly to phase 3. Detailed results will be presented at a medical conference in 2026.

community Positive Hair Result in Patient using Tirzepatide

4 upvotes 1 year ago

A 57-year-old man with male pattern hair loss and insulin resistance experienced hair regrowth and weight loss after using tirzepatide, without other hair treatments. Dysregulated glucose metabolism is linked to hair loss, with tirzepatide potentially improving hair density by normalizing insulin resistance.

community when is kintor going to start phase 3 for gt20029?

6 upvotes 2 years ago

The conversation is about the timeline for Kintor's phase 3 trials for GT20029 and the potential release of the product in three years. It also mentions treatments like Minoxidil, finasteride, and RU58841.