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GlossaryAndrogen Suppression (Testosterone Suppression)

reducing or blocking male hormones to slow cancer growth

Androgen Suppression, also known as Androgen Deprivation Therapy (ADT), involves reducing or blocking the action of androgens (male hormones like testosterone) to slow the growth of certain cancers, such as prostate cancer. This can be achieved through medications that inhibit androgen production or through surgical procedures like orchiectomy (removal of the testes).

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community Comparing the effect of T suppression and DHT suppression

in Transgender 52 upvotes 6 months ago

Trans women discuss using finasteride and dutasteride for hair loss and whether to continue after testosterone suppression. One user reduced dutasteride dosage after achieving undetectable testosterone levels.

community Comparing the effect of T suppression and DHT suppression

in Transgender 76 upvotes 6 months ago

The conversation discusses the use of 5-alpha-reductase inhibitors like finasteride and dutasteride for hair loss in transgender women, particularly in relation to testosterone suppression. The original poster has been using dutasteride and is considering stopping it due to undetectable testosterone levels.

community Dont stop using Minoxidil i beg you! Dont be fool like me.

in Minoxidil 507 upvotes 3 months ago

Stopping minoxidil causes significant hair loss, as continued use is necessary for maintaining gains. Combining minoxidil with finasteride may help maintain hair, but both treatments are typically lifelong commitments.

community Do hair follicles ever really "die"? Or does all your front, mid, and crown hair just become vellus?

in Chat 139 upvotes 5 months ago

Hair follicles don't truly die but become severely miniaturized. Treatments like finasteride, dutasteride, and minoxidil can help restore hair by providing nutrients and reducing harmful effects on hair roots.

community If Minoxidil Beards are permanent, why should Finasteride be unable to keep Minoxidil Gains on the scalp?

in Minoxidil 104 upvotes 2 years ago

Whether Finasteride can keep alive the hair gained by Minoxidil after quitting it, and why beard hairs are not as susceptible to miniaturization. It is suggested that scalp hair may be dependent on Minoxidil and that DHT could be countered with Finasteride to some extent, but there is no definitive data proving this.

community Is 2years+ telogen effluvium possible?

in Finasteride/Dutasteride 2 upvotes 6 months ago

The user has been losing hair for over two years despite taking dutasteride and RU58841, even increasing dutasteride to 2.5mg. They are questioning if their hair loss could be due to telogen effluvium instead.

community Why creatine and gym cause MPD

in Finasteride/Dutasteride 1 year ago

Gym and creatine can cause hair loss by increasing testosterone and androgenic activity. DHT blockers may help some, while others need androgen suppression with topical AA like RU or Pyri.

community Testosterone in Reference Range Doesn't Cause Hair Loss

in Research/Science 51 upvotes 11 months ago

Testosterone within the normal range does not significantly contribute to male pattern baldness (MPB); DHT is the main factor that can be controlled. Genetics play a crucial role in hair loss, and treatments like finasteride and dutasteride, which block DHT, can help despite potentially raising testosterone levels.

community DHT/Testosterone levels in scalp Fin VS Dut.

in Finasteride/Dutasteride 65 upvotes 6 months ago

Dutasteride raises scalp testosterone by 99%, which may not be ideal for those sensitive to all androgens. Some argue finasteride's balancing act might be better, while others believe dutasteride is superior for hair regrowth.

community Dutasteride , bloodwork and dht.

in Finasteride/Dutasteride 16 upvotes 8 months ago

The user reported high testosterone and estradiol levels within range, but unexpectedly high DHT levels after using finasteride and dutasteride for hair loss. Another person suggested the dutasteride might be fake or a bad batch and recommended using the branded Avodart.

community Since Dutasteride is dose dependent, is there any real difference in taking 0.5mg daily vs every other day?

in Finasteride/Dutasteride 16 upvotes 2 months ago

Taking dutasteride daily at higher doses results in more effective DHT suppression compared to every other day dosing, due to its dose-dependent nature and long half-life. Even at lower doses, dutasteride is more effective than finasteride for hair loss.

community Does Ashwagandha cause hair loss?

in Chat 24 upvotes 1 year ago

User asks if Ashwagandha causes hair loss while using Finasteride and Minoxidil. Replies suggest Ashwagandha may increase shedding, but raising testosterone within normal levels likely won't significantly affect hair loss.

community Does Nuking Scalp DHT Theoretically Make Minoxidil Gains Permanent?

in Minoxidil 36 upvotes 2 months ago

Minoxidil gains are not permanent without continued use, even with DHT suppression. Combining treatments like Dutasteride, Finasteride, and RU58841 may help maintain hair, but stopping Minoxidil typically results in hair loss.

community Anything stronger than DUT out there?

in Finasteride/Dutasteride 14 upvotes 10 months ago

The conversation discusses seeking a stronger treatment than Dutasteride (DUT) for hair loss. Suggestions include combining DUT with RU58841, increasing DUT dosage, and using transgender hormone replacement therapy or testosterone blockers, though some options may have feminizing side effects.

community my Body hair has stopped working

in Finasteride/Dutasteride 44 upvotes 11 months ago

A user on dutasteride for hair loss noticed hair regrowth on their head but a significant reduction in body hair growth. They plan to switch to finasteride and dutasteride and are considering testosterone replacement therapy but are concerned about its effects on hair growth.

community I am horny as hell due to fin.

in Finasteride/Dutasteride 225 upvotes 1 year ago

Some individuals taking finasteride for hair loss report increased libido and frequent masturbation, with no immediate hair regrowth but darker hair appearance. A dermatologist explains that finasteride may raise testosterone levels temporarily, which could lead to increased sex drive in some people.

community Dutasteride High Libido. How come we don't talk about this?

in Finasteride/Dutasteride 208 upvotes 3 months ago

Dutasteride and finasteride can affect libido differently, with some experiencing increased libido and others decreased libido or erectile dysfunction. Dutasteride may increase testosterone levels but can also cause side effects like liver enzyme changes, while topical finasteride may have fewer sexual side effects.

community How to Keep Your Hair on Steroids

in Treatment 17 upvotes 4 months ago

To minimize hair loss while using steroids, use finasteride or dutasteride and apply topical anti-androgens like RU58841. Avoid high doses of hair-toxic steroids; prefer testosterone, nandrolone, and boldenone.

community Discussion: High DHT levels while on Fin+Dut with substantial progress (pics)

in Progress Pictures 63 upvotes 2 years ago

A user's experience with using 5AR inhibitors (Finasteride and Dutasteride) in combination with Minoxidil foam and microneedling, which resulted in substantial improvements to their crown density and hairline, despite high systemic levels of testosterone and dihydrotestosterone.

community Gyno & testoterone level

in Finasteride 282 upvotes 7 months ago

Switching from finasteride to dutasteride and back to finasteride led to gynecomastia and fatigue, likely due to hormonal imbalances. Suggested treatments include Tamoxifen, Raloxifene, or low-dose Anastrozole, with a recommendation to test testosterone and estradiol levels.

community 16month progress on crazy stack

in Finasteride/Dutasteride 8 upvotes 1 year ago

The user has been using a strong combination of hair loss treatments for 16 months, including Finasteride, Minoxidil, Dutasteride, and RU-58841, but their hair loss has worsened. They're questioning whether their high testosterone levels or residual scalp DHT are causing further hair loss, with a reply suggesting that even small amounts of DHT can cause hair loss if one is sensitive to it.

community Ultimate Stack without nuking your gender (you'll go broke)

in Treatment 84 upvotes 1 month ago

A hair loss treatment plan includes finasteride, dutasteride, RU58841, pyrilutamide, minoxidil, and microneedling to inhibit DHT and promote hair growth. It also recommends supplements like Reishi and Lion’s Mane mushrooms, and a shampoo with ketoconazole, caffeine, and melatonin.

community Feeling energyless and think my 2.5mg dut per day might be causing it

in Research/Science 20 upvotes 4 months ago

Taking 2.5mg of dutasteride daily can cause feelings of low energy, ambition, and motivation, likely due to hormonal imbalances. Many users suggest lowering the dose to 0.5mg to alleviate these side effects.

community Shouldn’t it be impossible for dutasteride to make hair loss worse?

in Finasteride/Dutasteride 39 upvotes 5 months ago

Dutasteride is unlikely to worsen hair loss; shedding is often temporary. Other factors like inconsistent use, placebo effect, or additional treatments may influence perceived results.

community Let's talk about natural options and last resorts.

in Chat 7 upvotes 8 months ago

The user discusses their long struggle with hair loss, considering various treatments like hair transplants, hair systems, and natural methods such as micro-needling, vitamin supplements, and a healthy lifestyle. They express concerns about side effects from drugs like finasteride and ultimately lean towards using a hair system for better appearance and confidence.

community Finasteride increase in Estradiol?

in Update 17 upvotes 11 months ago

A user experienced increased estradiol, nipple tenderness, and ED after taking finasteride. They are considering dose reduction to mitigate these effects.

community Are these all the anti androgen products?

in Treatment 6 upvotes 1 year ago

The conversation lists hair loss treatments including finasteride, dutasteride, RU58841, pyrilutamide, breezula, and fluridil, and suggests ketoconazole as another option. Some users warn against using certain treatments like cyproterone acetate, bicalutamide, and spironolactone due to their strong anti-androgen effects and potential impact on masculinity.

community Should I start Fin with these blood tests?

in Finasteride/Dutasteride 17 upvotes 1 year ago

A 25-year-old male with normal hormone levels is considering starting finasteride and minoxidil for hair loss but is concerned about high estradiol levels and potential side effects. Responses vary, with some suggesting blood tests before starting treatment and others emphasizing individual tolerance and the importance of consulting a doctor.

community Ru, Stemoxydine or Alfatradiol? What has your experience been with any of these 3?

in Treatment 3 upvotes 1 year ago

The user is seeking advice on which treatment to add to their current regimen for male pattern baldness. They have previously tried Dutasteride, Nizoral, and oral Minoxidil, but experienced continued hair loss. They are specifically asking for experiences with RU58841, Stemoxydine, or Alfatradiol.

community [19M] Before and after pics 8 months after consistent use of Finasteride 1 mg and Minoxidil 5% 1ml every night, ketokonazole2%+salicylic acid mild shampoo everyday. I've used minoxidil only for the frontal, most significant area of the scalp for regrowth as 1 ml is not enough for entire scalp

in Progress Pictures 223 upvotes 3 years ago

User shared before and after photos of 8 months using Finasteride 1mg and Minoxidil 5% 1ml nightly, with positive results and no side effects. Others praised the progress and suggested alternative treatments like topical fin, CB-03-01, or RU58841.