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      community How to Keep Your Hair on Steroids

      in Treatment  16 upvotes 2 months ago
      To minimize hair loss while using steroids, use finasteride or dutasteride and apply topical anti-androgens like RU58841. Avoid high doses of hair-toxic steroids; prefer testosterone, nandrolone, and boldenone.
      FCE 28260: A Forgotten 5α-Reductase Inhibitor

      community FCE 28260: A Forgotten 5α-Reductase Inhibitor

      in Research  330 upvotes 3 months ago
      FCE 28260 (PNU 156765), an under-explored 5α-reductase inhibitor, showcases promising results in research by Giudici et al., outperforming well-known treatments like Finasteride in reducing the conversion of testosterone to DHT. Its superior efficacy, demonstrated through lower IC50 values in both natural and human recombinant enzyme studies, suggests it could offer more effective management of DHT-related conditions. Additionally, its lower molecular weight hints at better potential for topical application, potentially offering advantages in treating conditions such as androgenic alopecia. Despite its potential, it has not advanced in development, possibly due to financial limitations, leaving its therapeutic prospects and side effect profile largely unexplored.

      community From June 22 to August 23 slowww progress

      in Progress Pictures  13 upvotes 1 year ago
      The conversation is about a person's slow progress in treating hair loss using finasteride, microneedling, testosterone replacement therapy, dutasteride, RU58841, and minoxidil. They experienced a significant hair shed after adding dutasteride.

      community Does Ashwagandha cause hair loss?

      in Chat  24 upvotes 1 year ago
      User asks if Ashwagandha causes hair loss while using Finasteride and Minoxidil. Replies suggest Ashwagandha may increase shedding, but raising testosterone within normal levels likely won't significantly affect hair loss.

      community Blood DHT Levels – before and after creatine

      in Research/Science  41 upvotes 1 year ago
      The impact of creatine on DHT levels, and whether it could cause accelerated male pattern baldness (MPB). The user taking a 5 alpha reductase inhibitor found that their DHT levels actually reduced despite taking creatine for nine weeks. Replies suggested looking into testosterone levels as well and debating the safety of creatine use in relation to MPB.

      community Gyno & testoterone level

      in Finasteride  282 upvotes 5 months ago
      Switching from finasteride to dutasteride and back to finasteride led to gynecomastia and fatigue, likely due to hormonal imbalances. Suggested treatments include Tamoxifen, Raloxifene, or low-dose Anastrozole, with a recommendation to test testosterone and estradiol levels.

      community Dutasteride 1 year regression. Depressing. (With pictures for proof)

      in Progress Pictures  14 upvotes 11 months ago
      A user shared their experience of hair loss progression after one year on dutasteride, expressing disappointment with no improvement and considering other treatments like RU58841. Other users offered mixed responses, some seeing no change, others suggesting the hair loss might have been worse without treatment, and discussing the role of testosterone and DHT in hair loss.

      community 16month progress on crazy stack

      in Finasteride/Dutasteride  8 upvotes 1 year ago
      The user has been using a strong combination of hair loss treatments for 16 months, including Finasteride, Minoxidil, Dutasteride, and RU-58841, but their hair loss has worsened. They're questioning whether their high testosterone levels or residual scalp DHT are causing further hair loss, with a reply suggesting that even small amounts of DHT can cause hair loss if one is sensitive to it.

      community Long term results are real: 11 years on fin. then dut. + min. then oral min. - first pic at 18 with massive miniaturization and the others last night at 29

      in Progress Pictures  758 upvotes 1 year ago
      The conclusion of the conversation is that the user, who has been using finasteride for 11 years and then switched to dutasteride and minoxidil, has experienced minimal side effects and significant hair regrowth. They also mention that side effects are rare and often related to other factors such as poor diet and low testosterone levels.

      community My hair after 3 steroid cycles

      in Progress Pictures  26 upvotes 4 months ago
      A user shared their hair progress after three steroid cycles, using 5% minoxidil and 100mg RU58841 daily. They are considering a hair transplant due to paranoia about shedding.

      community High Nicotine use and Hair Loss

      in Chat  79 upvotes 3 months ago
      Heavy nicotine use can lead to hair thinning and loss, but quitting can reverse these effects. The user noticed significant hair regrowth after quitting vaping.

      community Give me courage, friends! / Is finasteride response correlated with aggressiveness of hair loss?

      in Finasteride/Dutasteride  6 upvotes 1 year ago
      The user has been using topical finasteride for seven months and minoxidil for three years, with added tretinoin gel for ten months, and is experiencing continuous shedding without signs of regrowth. They are questioning if the amount of shedding is normal at this stage of treatment and if there's a correlation between finasteride response and the rate of hair loss.

      community Pyrilutamide - your experience?

      in Product  12 upvotes 1 year ago
      The conversation is about the lack of improvement in hair loss after using Pyrilutamide for 14 weeks, with the original poster unable to use Finasteride due to depression. Replies suggest that Pyrilutamide, like RU58841, may not work for everyone, and a more potent drug is being developed by Kintor.

      community Ru-58841 vs KX-826/pyrilutamide while on steroids

      in Finasteride/Dutasteride  3 upvotes 3 weeks ago
      The user increased their steroid dosage and noticed hair shedding, so they adjusted their regimen by reducing steroid doses and adding oral dutasteride. They are also experimenting with combining RU-58841 and KX-826/pyrilutamide in minoxidil to address hair loss.

      community RU58841 alone vs. with Fin / Dut

      in Finasteride/Dutasteride  11 upvotes 1 year ago
      RU58841 combined with finasteride or dutasteride is more effective than RU58841 alone for hair loss. Users suggest combining these with minoxidil and microneedling for better results.

      community does lowering your prolactin levels regrow hair?

      in Research/Science  9 upvotes 1 year ago
      The potential of lowering prolactin levels to regrow hair, with a reference to Bayer's drug HMI 115 which has been indicated as having this effect. Treatments mentioned include Minoxidil and Finasteride, as well as RU58841.

      community I’ve been using min and nizoral for 7 years, losing a lot of hair in the meantime. Here’s what happened when I added 1mg fin daily and 1.5mm micro needling weekly.

      in Progress Pictures  211 upvotes 2 years ago
      The positive effects of Finasteride, a hair loss treatment; and various other treatments such as Minoxidil and Nizoral that can be used to treat hair loss. Additionally, other methods are discussed, such as micro needling and taking spearmint supplements, which have been seen to help in some cases.

      community Zix + Topical Fin : Blood Test Before/After, AMA and suggestions

      in Treatment  49 upvotes 4 years ago
      A user's plan to use Zix and topical finasteride (5AR inhibitors) for hair loss, followed by blood testing before/after. The user has suggested creating a fund to cover part of the cost of their blood tests. Replies to their post discuss the effectiveness of the treatments.

      community 3 month into 2.5mg dutasteride - no hairs fall out of my head anymore

      in Technology  37 upvotes 1 month ago
      OP reports that after 3 months on 2.5mg dutasteride, their hair has stopped falling out and is thick again, but they are considering stopping due to potential mood and energy side effects. Other users discuss experiences with finasteride, dutasteride, and side effects, with some suggesting lower doses or alternative treatments like topical applications.