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      community High DHT with finasteride. Help!

      in Finasteride/Dutasteride  6 upvotes 11 months ago
      Despite using 5% minoxidil, 0.1% finasteride, and other treatments like microneedling, MK-677, and Cialis, hair loss continues with high testosterone and DHT levels. Considering oral dutasteride but concerned about further increasing testosterone levels.
      FCE 28260: A Forgotten 5α-Reductase Inhibitor

      community FCE 28260: A Forgotten 5α-Reductase Inhibitor

      in Research  330 upvotes 4 months ago
      FCE 28260 (PNU 156765), an under-explored 5α-reductase inhibitor, showcases promising results in research by Giudici et al., outperforming well-known treatments like Finasteride in reducing the conversion of testosterone to DHT. Its superior efficacy, demonstrated through lower IC50 values in both natural and human recombinant enzyme studies, suggests it could offer more effective management of DHT-related conditions. Additionally, its lower molecular weight hints at better potential for topical application, potentially offering advantages in treating conditions such as androgenic alopecia. Despite its potential, it has not advanced in development, possibly due to financial limitations, leaving its therapeutic prospects and side effect profile largely unexplored.

      community Ultimate Stack without nuking your gender (you'll go broke)

      in Treatment  84 upvotes 1 month ago
      A hair loss treatment plan includes finasteride, dutasteride, RU58841, pyrilutamide, minoxidil, and microneedling to inhibit DHT and promote hair growth. It also recommends supplements like Reishi and Lion’s Mane mushrooms, and a shampoo with ketoconazole, caffeine, and melatonin.

      community High Nicotine use and Hair Loss

      in Chat  84 upvotes 4 months ago
      Heavy nicotine use can lead to hair thinning and loss, but quitting can reverse these effects. The user noticed significant hair regrowth after quitting vaping.

      community Stem Cells May Get Rid Of Balding FOREVER!

      in Technology  7 upvotes 6 months ago
      Stem cell therapy shows promise in treating hair loss by mimicking DHT-resistant cells from the back of the head. Traditional treatments like finasteride are also discussed, but stem cells could potentially offer a more permanent solution.

      community 15 years of finasteride/minoxidil

      in Update  194 upvotes 8 months ago
      A user shared a 15-year experience using minoxidil and finasteride for hair loss, stating that despite never missing a dose, their hairline continued to recede slowly. Other users suggested that the hair loss might be exacerbated by the use of steroids and recommended considering other treatments like dutasteride and RU58841.

      community 1 year later, min 2ml daily, fin 1mg to 0.5 daily + microneedling

      in Finasteride/Dutasteride  147 upvotes 1 year ago
      The user, Salt_Ad6339, shares their positive experience with hair regrowth after using minoxidil and finasteride for a year, along with microneedling. However, they also mention experiencing chest/nipple pain and suspect it may be a side effect of finasteride. They decide to stop using it for now and see if minoxidil alone can maintain their hair. Other users in the conversation discuss the potential side effects of finasteride and suggest using an aromatase inhibitor to counteract them.

      community I find it funny a bunch of us on here are on drugs for hairloss and maintain clean/healthy lives and then there’s these mf’s in the 90’s juiced to the gills with steroids and have better hair than all of us lol

      in Satire  353 upvotes 1 year ago
      The conversation is about the effects of steroids on hair loss. Some users believe that steroids can cause hair loss, while others argue that it depends on individual sensitivity to DHT. There is also discussion about the appearance of balding individuals who use steroids.

      community Nandrolone Replacement Therapy

      in Treatment  41 upvotes 1 year ago
      A user discusses starting nandrolone replacement therapy to stop hair loss and improve hair health, noting its benefits over finasteride. They report halted hair loss, improved skin, increased muscle, and a calm mood after three weeks.

      community Zix + Topical Fin : Blood Test Before/After, AMA and suggestions

      in Treatment  45 upvotes 4 years ago
      A user's plan to use Zix and topical finasteride (5AR inhibitors) for hair loss, followed by blood testing before/after. The user has suggested creating a fund to cover part of the cost of their blood tests. Replies to their post discuss the effectiveness of the treatments.

      community How I started reversing Male Pattern Baldness naturally ?

      in Question  6 upvotes 7 years ago
      The user reversed male pattern baldness using a pro-thyroid diet, lifestyle changes, and scalp stimulation exercises, without Minoxidil or Finasteride. They reported reduced dandruff, itchiness, oiliness, and experienced hair regrowth and thickening over 15 months.

      community Pyrilutamide ,the molecule’s true nature

      in Research  302 upvotes 4 months ago
      Pyrilutamide is a selective AR antagonist with a high binding affinity, making it effective in competing with DHT for androgen receptors. The 1% concentration is more effective than the 0.5%, but the latter may suffice for mild hair loss; the drug is considered a good option for those avoiding 5AR blockers due to side effects.

      community I enjoy taking finasteride every day

      in Finasteride/Dutasteride  241 upvotes 8 months ago
      Users discuss their positive experiences with finasteride for hair loss, mentioning halted hair loss, hair regrowth, and improved self-esteem. Some express satisfaction in taking action against baldness, while others note increased libido and energy.

      community Let's talk about natural options and last resorts.

      in Chat  7 upvotes 8 months ago
      The user discusses their long struggle with hair loss, considering various treatments like hair transplants, hair systems, and natural methods such as micro-needling, vitamin supplements, and a healthy lifestyle. They express concerns about side effects from drugs like finasteride and ultimately lean towards using a hair system for better appearance and confidence.

      community What else can I do to compliment Minoxidil?

      in Update  4 upvotes 1 year ago
      A user has been using minoxidil for hair loss and has seen positive results, but is seeking additional treatments to enhance its effects. One suggestion given is to use finasteride alongside minoxidil.

      community 1 year results finasteride and minoxidil once daily nothing else

      in Update  848 upvotes 2 months ago
      The user experienced significant hair regrowth after one year of using finasteride, minoxidil, and Nizoral shampoo, with no side effects reported. They noted improved social interactions and emphasized the importance of consistency in treatment.

      community Does finasteride/dutasteride reverse aging?

      in Chat  45 upvotes 2 months ago
      Finasteride and dutasteride can improve skin texture and reduce acne by lowering DHT but do not reverse aging. They may enhance skin and hair health for some, but can also cause side effects like dry skin and sexual dysfunction.

      community 10.5 months. Oral propecia, topical minoxidil (once daily) derma roller. And for the last two (2) months, I've been doing the bald showers after leg workouts... Biotin and Omega 3 age 35. Loses a lot of hair a day, over 150

      in Progress Pictures  243 upvotes 5 months ago
      A user shared their 10.5-month progress using oral finasteride, topical minoxidil, a derma roller, biotin, and Omega 3, despite losing over 150 hairs daily. They also mentioned starting "bald showers" after leg workouts for the last two months.

      community A hill on which I will die: The DHT itch absolutely exists

      in Research/Science  209 upvotes 7 months ago
      The DHT itch is linked to hair loss and persists despite finasteride use; switching to dutasteride helped alleviate the itch and promoted regrowth. Some users suggest seborrheic dermatitis as a cause and recommend treatments like medicated shampoos, vitamin D, and minoxidil.

      community One year later, fin won't work for everyone

      in Progress Pictures  77 upvotes 8 months ago
      The conversation is about a user's experience with finasteride not improving their hair loss and considering dutasteride as a last resort. Some users believe the user's hair appears stabilized, while others suggest surgery or patience, and one mentions heart issues as a reason for not using minoxidil.

      community Creatine's effect on Hair Loss and DHT

      in Research/Science  100 upvotes 10 months ago
      A 21-year-old male managed to control his hair loss using Nizoral, RU58841, and finasteride, but experienced increased scalp itchiness after starting creatine, which subsided upon stopping creatine. Users shared mixed experiences on whether creatine affects hair loss, with some reporting negative effects and others seeing no change or defending its benefits.

      community What’s your experience with RU58841?

      in Treatment  21 upvotes 1 year ago
      People shared mixed experiences with RU58841 for hair loss; one person saw no improvement, another had significant gains and uses it with finasteride, while a third had an allergic reaction to the premixed solution. Some mix RU58841 powder into minoxidil themselves.