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      community Dutasteride High Libido. How come we don't talk about this?

      in Finasteride/Dutasteride  206 upvotes 3 weeks ago
      Dutasteride and finasteride can affect libido differently, with some experiencing increased libido and others decreased libido or erectile dysfunction. Dutasteride may increase testosterone levels but can also cause side effects like liver enzyme changes, while topical finasteride may have fewer sexual side effects.

      community Question about medications ...

      in Finasteride/Dutasteride  2 upvotes 1 month ago
      Hair loss treatments like spironolactone often require lifelong use to maintain results. Stopping the medication can lead to increased testosterone levels and potential hair loss.
      FCE 28260: A Forgotten 5α-Reductase Inhibitor

      community FCE 28260: A Forgotten 5α-Reductase Inhibitor

      in Research  330 upvotes 2 months ago
      FCE 28260 (PNU 156765), an under-explored 5α-reductase inhibitor, showcases promising results in research by Giudici et al., outperforming well-known treatments like Finasteride in reducing the conversion of testosterone to DHT. Its superior efficacy, demonstrated through lower IC50 values in both natural and human recombinant enzyme studies, suggests it could offer more effective management of DHT-related conditions. Additionally, its lower molecular weight hints at better potential for topical application, potentially offering advantages in treating conditions such as androgenic alopecia. Despite its potential, it has not advanced in development, possibly due to financial limitations, leaving its therapeutic prospects and side effect profile largely unexplored.

      community What blood exams should I do on dut/oral min

      in Chat  1 upvotes 4 months ago
      The user checked iron, ferritin, B12, zinc, testosterone, DHT, and estrogens to understand hair loss causes and the effects of dutasteride. They also noted increased heart rate and paleness with oral minoxidil.

      community Topical Spironolactone 5% effectiveness

      in Product  2 upvotes 4 months ago
      Topical spironolactone 5% is being discussed for its effectiveness in treating hair loss, specifically receding temples. The user is inquiring if it works similarly to finasteride as a testosterone blocker.

      community How’s my pre fin lab work. Age 40

      in Chat  6 upvotes 5 months ago
      A user shared their pre-finasteride lab results, including DHT, estradiol, testosterone, SHBG, prolactin, FSH, and LH levels. Another user responded, cautioning against making unsupported claims about side effects and recovery.

      community Topical Dutasteride - DHT Levels

      in Finasteride/Dutasteride  2 upvotes 6 months ago
      A user reported using a topical hair loss treatment containing Minoxidil, Dutasteride, and other ingredients, noting a significant drop in DHT levels and a smaller decrease in testosterone after three months. They also mentioned microneedling, feeling fine with unchanged or increased libido, and taking Cialis as a preventative measure for performance issues.

      community Fin for 1 year+ no results, non-responder?

      in Finasteride/Dutasteride  10 upvotes 7 months ago
      A user has been on finasteride for over a year with minimal hair regrowth and is considering stopping it, despite no side effects. They are also planning a hair transplant and seeking additional hair growth treatments, while managing high testosterone and scalp issues like dandruff and oiliness.

      community 52M completed my first 30 day on 5% topical Minoxidil

      in Progress Pictures  37 upvotes 7 months ago
      A 52-year-old man has been using 5% Minoxidil twice daily for 30 days to treat hair loss, alongside 2.5mg Finasteride, which he reduced from 5mg despite his doctor's advice. He has a history of hair loss due to testosterone treatment and hopes to see improvement in the crown area of his scalp.

      community Reasonable and safe stack? Bloodwork within.

      in Minoxidil  1 upvotes 8 months ago
      A 26-year-old male is using a combination of clomiphene, minoxidil, tadalafil, bupropion, and lisdexamfetamine to address low testosterone, ED, depression, and focus issues. He seeks input on the safety and efficacy of this regimen, which also includes magnesium, zinc, and fish oil supplements.

      community High DHT with finasteride. Help!

      in Finasteride/Dutasteride  6 upvotes 9 months ago
      Despite using 5% minoxidil, 0.1% finasteride, and other treatments like microneedling, MK-677, and Cialis, hair loss continues with high testosterone and DHT levels. Considering oral dutasteride but concerned about further increasing testosterone levels.

      community Topical finasteride has affected my hormones

      in Finasteride/Dutasteride  26 upvotes 10 months ago
      A 21-year-old experienced hormone changes after using self-made topical finasteride for hair loss, including a 20% decrease in DHT, a 47% increase in testosterone, and a 39% increase in estradiol. The user previously used minoxidil and microneedling but is now seeking ways to balance hormones, possibly through supplements or dosage adjustments.

      community I am horny as hell due to fin.

      in Finasteride/Dutasteride  225 upvotes 10 months ago
      Some individuals taking finasteride for hair loss report increased libido and frequent masturbation, with no immediate hair regrowth but darker hair appearance. A dermatologist explains that finasteride may raise testosterone levels temporarily, which could lead to increased sex drive in some people.

      community Should I start fin with these blood tests?

      in Finasteride/Dutasteride 11 months ago
      A 25-year-old male is concerned about his blood test results, particularly the low percentage of free testosterone, and is questioning whether starting finasteride for hair loss might worsen this issue. He also notes a slight vitamin D deficiency and lack of sleep before the test.

      community Does ashwagandha improve or worsen MPB hair loss

      in Chat  1 upvotes 1 year ago
      The post discusses the impact of Ashwagandha on hair loss, highlighting its ability to lower stress levels, which is beneficial for hair health. However, there's uncertainty about its potential to increase testosterone and DHT, which could contribute to hair loss.

      community From June 22 to August 23 slowww progress

      in Progress Pictures  13 upvotes 1 year ago
      The conversation is about a person's slow progress in treating hair loss using finasteride, microneedling, testosterone replacement therapy, dutasteride, RU58841, and minoxidil. They experienced a significant hair shed after adding dutasteride.

      community A Technical Question About Pyrilutamide

      in Research/Science  5 upvotes 1 year ago
      Pyrilutamide is believed to be more effective than RU58841 and 1 mg finasteride in treating hair loss, with no systemic hormonal effects and the potential to block more than 31% of scalp DHT. It may also antagonize scalp testosterone due to its action as an androgen receptor antagonist.

      community Does Ashwagandha cause hair loss?

      in Chat  24 upvotes 1 year ago
      User asks if Ashwagandha causes hair loss while using Finasteride and Minoxidil. Replies suggest Ashwagandha may increase shedding, but raising testosterone within normal levels likely won't significantly affect hair loss.

      community Blood DHT Levels – before and after creatine

      in Research/Science  41 upvotes 1 year ago
      The impact of creatine on DHT levels, and whether it could cause accelerated male pattern baldness (MPB). The user taking a 5 alpha reductase inhibitor found that their DHT levels actually reduced despite taking creatine for nine weeks. Replies suggested looking into testosterone levels as well and debating the safety of creatine use in relation to MPB.