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      community Do you guys deal with tingling

       4 upvotes 5 days ago
      A 21-year-old male has been experiencing hair loss with tingling sensations and has been using oral finasteride, minoxidil, and coal tar shampoo. Finasteride has reduced tingling, but thinning persists, and others suggest possible DHT-related inflammation and recommend treatments like dutasteride and ketoconazole shampoo.

      community Update for PP405 - phase 2b underway

       122 upvotes 1 year ago
      PP405 is advancing to Phase 2b trials, showing promise from Phase 2a. It may be available in 3-6 years, with trials using a topical gel.

      community Best Tretinoin for Topical Minoxidil

       5 upvotes 2 weeks ago
      Tretinoin can enhance the effects of topical minoxidil for hair loss, with Altreno recommended for its less irritating formula. Users suggest applying tretinoin first, waiting 20 minutes, then applying minoxidil or finasteride.

      community European release of clascoterone

       13 upvotes 4 months ago
      Clascoterone's European release is expected in Q4 2026, with FDA approval anticipated by mid-2027. The discussion includes questions about the approval timeline and potential acceleration due to unmet needs.

      community Just had my first dermatologist appointment - unsure on Oral Minox vs Compounded Min/Fin/Tret (while already on Dut)

      in Minoxidil  2 upvotes 1 year ago
      A 28-year-old male, previously on dutasteride for hair loss, is considering oral minoxidil or a compounded treatment of minoxidil, finasteride, and tretinoin after noticing hairline recession. The dermatologist suggested oral minoxidil and mentioned a compounded option, but the user is unsure about its benefits compared to current treatments.

      community My home made topical dutasteride

      in Finasteride/Dutasteride  3 upvotes 1 year ago
      The conversation is about a user making a homemade topical dutasteride solution to use alongside testosterone replacement therapy (TRT) and oral dutasteride. The user aims to reduce DHT locally at the testosterone injection site and on the scalp.

      community What do we currently know about clascoterone?

       7 upvotes 8 months ago
      Clascoterone is seen as a promising topical treatment for hair loss, similar to finasteride but without side effects, though concerns exist about its long-term effectiveness. Other treatments discussed include topical minoxidil, ketoconazole, microneedling, and oral options like dutasteride and minoxidil.

      community What kind of tretinoin should i get?

       1 upvotes 9 months ago
      OP is seeking advice on which percentage of tretinoin to use to enhance the effectiveness of minoxidil for hair loss. They are unsure about choosing between 0.1%, 0.025%, or 0.05% tretinoin.

      community Tretinoin and minoxidil. How do you guys use this combo

       14 upvotes 1 year ago
      Tretinoin is used with minoxidil to enhance hair growth, with some users applying tretinoin before minoxidil to improve results. Some users report success with this combination, while others experience irritation or dryness.

      community Switching from oral to topical dut

      in Finasteride/Dutasteride  1 upvotes 7 months ago
      Switching from oral to topical dutasteride can cause shedding due to changes in DHT levels, and it's recommended to overlap both treatments to minimize this effect. Topical dutasteride may cause scalp irritation, and the user is considering dutasteride mesotherapy as an alternative.

      community New to tretinoin, when to apply?

       2 upvotes 8 months ago
      The conversation is about using tretinoin to enhance the effectiveness of minoxidil for hair loss. Tretinoin should be applied at night on dry skin, and it can be used daily, either before or after minoxidil, with a starting dose of 0.025%.

      community My kotoconazole shampoo contain this

      6 months ago
      The conversation discusses the safety and use of ketoconazole shampoo for hair loss, with mentions of zinc pyrithione and selenium sulfide. Users debate the safety of these ingredients, particularly zinc pyrithione, and share opinions on regulatory differences between Europe and the US.

      community Anti androgen shed all over scalp

       3 upvotes 2 years ago
      The user is experiencing intense hair shedding all over the scalp after applying pyrilutamide to the hairline and taking oral castor oil. They are also using topical finasteride and latanoprost, but are unsure which treatment is causing the shedding.

      community PELAGE PHASE 2 TRIALS FOR PP405 - Volunteers Needed

       24 upvotes 2 years ago
      PP405 is a topical gel being tested for hair regrowth in adults with androgenetic alopecia. Volunteers aged 18-55 are needed for a 16-week trial in several US locations.

      community Scared of Oral Minoxidil Dread Shed

       1 upvotes 1 week ago
      A woman with PCOS, AGA, and TE is worried about hair loss from oral minoxidil (OM) and is considering topical treatment to avoid shedding. A user reassures her that while shedding may occur, it won't lead to baldness, just temporary thinning.

      community SUBE3 for sale in the gray market?

       5 upvotes 1 year ago
      SCUBE3 is available online but poses risks like tumor promotion and high costs. Users advise against using it due to health concerns and inefficacy as a standalone treatment.

      community Why was this compound abandoned ?

       1 upvotes 6 months ago
      KY19382, a promising compound for hair loss, is not widely discussed or used. One user is currently testing it and plans to share results in a few weeks.

      community PP405 ON TEMU....seriously come on

      in Satire  145 upvotes 5 months ago
      A fake hair loss product called "PP405" is being humorously discussed, with users joking about its effectiveness and availability on resale websites. The consensus is that it's a scam, with some users sarcastically claiming miraculous results.

      community M25 - Need Non alcoholic minoxidil options available in India

       1 upvotes 4 months ago
      The conversation is about finding non-alcoholic minoxidil options in India due to irritation from propylene glycol-based formulations. Suggestions include Tugain 5% foam, Morr Max 5%, minoxidil gel, and Morr F Aqua plus, with OP avoiding finasteride due to side effects.

      community Dutasteride 0.05% topical vs Finasteride 0.1% topical foam

       5 upvotes 1 year ago
      The conversation discusses two hair loss treatments: Minoxidil 5% with Azelaic Acid 1.5% and Dutasteride 0.05% topical foam, and Finasteride 0.1% with Minoxidil 5% topical foam. Users express uncertainty about the effectiveness of topical Dutasteride, while topical Finasteride is generally considered effective.

      community Sandalore experiment

       18 upvotes 7 years ago
      A user added sandalore to minoxidil for hair loss, observing some vellus hair growth and less scalp inflammation. Others tried sandalore with mixed results, discussing dosage and effectiveness compared to minoxidil and finasteride.

      community Started tretinoin, lost a bunch of new hairs - normal?

       37 upvotes 1 year ago
      The user experienced increased hair shedding after adding tretinoin to their regimen of finasteride, minoxidil, and dermarolling, but noticed new vellus hairs appearing. They plan to restart tretinoin more gently, as some users suggest shedding indicates treatment effectiveness, while others warn it may cause severe thinning for a minority.