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      community watch out, here comes the hair

      in Research/Science  564 upvotes 2 years ago
      A user's journey with hair loss and their use of topical finasteride, minoxidil and pyri/minoxidil ratio treatments to attempt hair regrowth. Replies focused on offering support and advice while sharing personal experiences with different treatments.

      community My microneedling journey (no min, fin, etc)

      in Microneedling  210 upvotes 5 months ago
      The user experienced positive hair growth results using microneedling with rosemary and mint oil, without Minoxidil, Finasteride, or RU58841. They switched from a dermaroller to a microneedling pen and targeted different scalp areas weekly.
      FCE 28260: A Forgotten 5α-Reductase Inhibitor

      community FCE 28260: A Forgotten 5α-Reductase Inhibitor

      in Research  330 upvotes 6 months ago
      FCE 28260 (PNU 156765), an under-explored 5α-reductase inhibitor, showcases promising results in research by Giudici et al., outperforming well-known treatments like Finasteride in reducing the conversion of testosterone to DHT. Its superior efficacy, demonstrated through lower IC50 values in both natural and human recombinant enzyme studies, suggests it could offer more effective management of DHT-related conditions. Additionally, its lower molecular weight hints at better potential for topical application, potentially offering advantages in treating conditions such as androgenic alopecia. Despite its potential, it has not advanced in development, possibly due to financial limitations, leaving its therapeutic prospects and side effect profile largely unexplored.

      community [26M] 3.5 year update. Fin+Min

      in Progress Pictures  3399 upvotes 8 months ago
      A user shared their 3.5-year hair loss treatment journey using finasteride and minoxidil, showing significant hair density improvement and no noticeable side effects. The user also mentioned the confidence boost from shaving their head and the positive impact of the treatments.

      community What do you think Jerry Seinfeld did to restore his hair?

      in Satire  937 upvotes 11 months ago
      The conversation speculates on how Jerry Seinfeld might have improved his hair appearance, suggesting various methods like hair styling, hair products, Minoxidil, Finasteride, and hair restoration, but no consensus is reached. Some comments are jokes, not serious suggestions.

      community What has helped you regrow your temples?

      in Chat  21 upvotes 1 year ago
      User seeks advice for regrowing temples, currently using Fin, oral Min, and dermarolling. Suggestions include improving scalp environment and considering RU58841 or dutasteride.

      community Homemade topical spironolactone

      in Research/Science  27 upvotes 2 years ago
      The potential effectiveness of homemade topical spironolactone in treating hair loss, with studies suggesting it is more effective than finasteride and even minoxidil when used as monotherapy. The conversation also mentions that other anti-androgens are being developed which may soon hit the market.

      community What 1 year and $6000 can do for your hair

      in Treatment  305 upvotes 2 years ago
      A hair transplant performed by Dr Bruno Ferreira in Portugal, which has improved the user's appearance and self-confidence. The user also mentioned taking finasteride for 5 years to help with their hair loss.

      community This serum outperformed Minoxidil in a recent study. Please debunk

       23 upvotes 5 years ago
      A topical solution called "Multi-Peptide Serum for Hair Density" by The Ordinary Company, which contains several ingredients that are used in alternatives to Minoxidil and was found to have better results than 5% Minoxidil in a study. People who have tried it shared their experiences with the serum as well.

      community Oils, Saw Palmetto, Microneedling every 3 days, DHT Shampoo

      in Progress Pictures  287 upvotes 2 months ago
      The user experienced positive hair regrowth using a routine of microneedling every 3 days, applying a blend of castor oil with peppermint and rosemary, bhringraj oil, and moringa oil, and using Pura D'Or DHT-blocking shampoo. They also take multivitamins and saw palmetto daily, reporting no side effects from saw palmetto.

      community What’s more reliable right now, pyrilutamide or RU?

      in Treatment  15 upvotes 2 years ago
      Treatments for hair loss, with the user considering Pyrilutamide and RU58841 as options. It is noted that although Pyrilutamide has been studied more and is allegedly more effective, there are doubts about its authenticity in the market. KX-826 is suggested as an alternative as it has a stronger effect than RU58841 and there is scientific research on it.

      community Met a doctor at the zoo who told me the TRUTH about Fin

      in Satire  748 upvotes 1 year ago
      A satirical post jokes about a user meeting a doctor at the zoo who praises finasteride (Fin) for hair loss treatment, claiming it has a low side-effect profile and is effective. Replies include humorous disbelief, comparisons to other risks, and some personal accounts of side effects from Fin.

      community Triple Hair TH-16 released. Thoughts and opinions?

      in Product  35 upvotes 3 years ago
      Triple Hair's TH-16, a product claimed to be more effective than Minoxidil 5%, has been released; it contains melatonin and resveratrol. One user reported success with topical melatonin and dermarolling.

      community 2 Weeks on Topical Melatonin .

      in Treatment  15 upvotes 3 years ago
      A user tried topical melatonin for hair loss and experienced significantly reduced shedding, similar to when they used finasteride, but stopped finasteride due to side effects. They applied liquid melatonin from a dropper and noticed a decrease in hair fall within two days.

      community My progress story for my hair loss treatment

      in Progress Pictures  403 upvotes 1 year ago
      User's hair loss treatment progress includes 1 mg finasteride, 2.5 mg minoxidil tablets twice daily, microneedling 3 times a week, and Fungoral shampoo twice weekly. Good progress and minimal side effects reported.

      community Pyrilutamide - one month update

      in Update  14 upvotes 2 years ago
      User on 5th week of Pyrilutamide and oral Minoxidil, no hair loss improvement yet. Others suggest waiting 3 months for results.

      community 26 male 1 year 9 month therapy (fin,min,dut, micro needling)

      in Progress Pictures  438 upvotes 3 months ago
      A 26-year-old male shared his hair loss treatment journey using finasteride, minoxidil, dutasteride, and microneedling, noting dissatisfaction with hair thickness but hoping for improvement. Users discussed side effects, treatment effectiveness, and shared personal experiences with similar treatments.

      community Dutasteride accelerated my hairloss, no shed tho

      in Finasteride/Dutasteride 1 week ago
      A user experienced worsening hair recession after adding 0.5 mg daily dutasteride to their regimen of topical minoxidil and finasteride, despite no initial shedding. They plan to continue monitoring the situation, as others suggest it may be too early to see results and recommend blood tests to check DHT levels.

      community So Pyrilutamide has been postponed by one year. How likely is that to happen to GT20029

      in Treatment  27 upvotes 1 year ago
      The conversation discusses the delay in the release of a new hair loss treatment, Pyrilutamide, and speculates on potential safety concerns as a reason for the delay. It also mentions GT20029 as another future treatment option, with a release at least five years away, and touches on the avoidance of research chemicals due to uncertainty about their authenticity.