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      community Pyrilutamide ,the molecule’s true nature

      in Research  302 upvotes 2 months ago
      Pyrilutamide is a selective AR antagonist with a high binding affinity, making it effective in competing with DHT for androgen receptors. The 1% concentration is more effective than the 0.5%, but the latter may suffice for mild hair loss; the drug is considered a good option for those avoiding 5AR blockers due to side effects.

      community Hello again with my second journey

      in Transplants  78 upvotes 6 months ago
      A user underwent a second hair transplant for increased density and to address hair loss in the crown area, with 3,800 grafts at a cost of 2,200 euros at Estepalace, including additional services. Some commenters discussed the appearance of the hairline and the importance of using DHT blockers like finasteride or dutasteride post-transplant.

      community Did quitting caffeine turn me into a minoxidil responder?

      in Minoxidil  2 upvotes 8 months ago
      A user shared that after quitting caffeine and restarting oral minoxidil, they experienced significant hair regrowth, suggesting that caffeine might interfere with minoxidil's effectiveness by blocking adenosine receptors. They also mentioned side effects like water retention and dizziness, which subsided after a few weeks, and are not using any DHT blockers.

      community Can you beat this 104 year old man‘s hair count?

      in Styling  751 upvotes 2 years ago
      A 104 year old man's impressive head of hair and speculations about how he has been able to maintain it; treatments such as minoxidil, finasteride, RU58841, dutasteride, 5-AR blockers, and other supplements are discussed.

      community CB-03-01 supposed hair loss cure

      in Treatment  8 upvotes 3 years ago
      The conversation discusses why CB-03-01, a potential hair loss treatment, isn't widely discussed despite evidence of its effectiveness and safety. Some users mention other treatments like melatonin, procianidin b2, and RU58841, debating their effectiveness and safety.

      community Update 6 months natural treatments

      in Is this regrowth? 3 months ago
      A user discusses their hair loss and current natural treatments, including derma stamp, rosemary oil, wild growth hair oil, biotin, omega 3, and a small DHT blocker. Another user suggests the hair loss is androgenic alopecia and recommends either taking finasteride or accepting the hair loss.

      community Results so far on Finasteride and biotin

      in Progress Pictures  145 upvotes 2 years ago
      The conversation is about someone experiencing significant hair regrowth after 23 days on Finasteride and Biotin, with others suggesting additional treatments like Minoxidil and microneedling. Some doubt the speed of hair growth, while others believe Biotin isn't contributing to the results.

      community Turning vellus hairs into terminal hair

      in Research/Science  12 upvotes 2 weeks ago
      People are discussing hair loss treatments, including minoxidil, finasteride, and RU58841, to turn vellus hairs into terminal hairs. Some users also mention using antibiotics, oral minoxidil, dutasteride, DHT blockers, biotin, and natural remedies like onion juice and seeds to improve hair growth.

      community LeBron James has the most mysterious hair

      in Progress Pictures  166 upvotes 2 months ago
      LeBron James likely uses hair transplants and possibly hair fibers or sprays to maintain his hairline, but his crown remains problematic. Despite his wealth, he hasn't fully resolved his hair loss, leading to speculation about his treatments and choices.

      community Does Ashwagandha cause hair loss?

      in Chat  24 upvotes 1 year ago
      User asks if Ashwagandha causes hair loss while using Finasteride and Minoxidil. Replies suggest Ashwagandha may increase shedding, but raising testosterone within normal levels likely won't significantly affect hair loss.

      community Minoxidil seems logistically impossible and impractical to use

      in Minoxidil  136 upvotes 1 year ago
      The post discusses concerns about the practicality of using Minoxidil foam for hair loss, including the frequency of application, preparation, coverage area, and drying time. Responses suggest that missing a dose isn't detrimental, it can be applied once a day, it works on all hair areas, and it doesn't need to be perfectly dry before application.

      community NW5 at 19. How many grafts do I need?

      in Transplants  140 upvotes 1 year ago
      A 19-year-old with rapid hair loss since 16 is considering a hair transplant but refuses to take finasteride or any 5α-Reductase inhibitors. They are currently using minoxidil, tretinoin, and microneedling with a Derminator 2, and only want hair until age 27.

      community Anybody using topical melatonin or zix in 2024?

      in Chat  12 upvotes 4 months ago
      The conversation is about using topical melatonin or zix for hair loss without affecting hormones. The user is seeking advice on which treatment is more effective.

      community Finasteride saved my life, 1.5y in (23M)

      in Progress Pictures  1178 upvotes 1 year ago
      The conclusion of the conversation is that some users have had positive results with finasteride for hair loss, while others have not. The effectiveness of finasteride varies from person to person.

      community Maintaining hair until Breezula without Fin

      in Treatment  6 upvotes 4 years ago
      A 21-year-old male experienced side effects from topical finasteride and is seeking alternative treatments to maintain hair until Breezula is available. He is considering using minoxidil, Nizoral, micro-needling, and vitamin D supplementation, and may try CB or RU58841 if necessary.

      community M23 , on finaestride and minoxidil for 4.8 months

      in Progress Pictures 1 year ago
      . This conversation is about a user's progress while using minoxidil and finasteride to treat hair loss, with emphasis on taking oral finasteride at night before bed for optimal results. They also discuss the brand of medication being used (Morr F 5%) and the importance of taking a generic version of the same drug.

      community where does the renewed spironolactone hype come from?

      in Research/Science  7 upvotes 1 year ago
      Topical spironolactone is gaining attention as an alternative hair loss treatment, but it's not as effective as other options like finasteride. Oral spironolactone can cause side effects in men, and there are better topical alternatives like RU, Pyril, and CB.

      community Parents think that I need a therapist because I obsess over my hair loss

      in Chat  75 upvotes 10 months ago
      A 19-year-old is concerned about going bald and disagrees with their parents who suggest therapy, believing hair loss will negatively impact their life. Some suggest therapy can help with the emotional aspects, while others support using finasteride and focusing on what makes the individual happy.

      community 17M Need y’all’s help with topical I was prescribed and what action to take

      in Treatment  1 upvotes 11 months ago
      A 17-year-old male experiencing significant hair loss is using a prescribed topical treatment containing Minoxidil, Tretinoin, Dutasteride, and Latanoprost. He expresses concerns about the potential side effects of Dutasteride and oral Finasteride, and seeks advice on whether to continue with the treatment or consider alternatives.

      community Dutasteride 2 years 3 month results

      in Finasteride/Dutasteride  251 upvotes 1 year ago
      The user tried dutasteride for hair loss for 2.5 years but experienced drastic thinning and receding hairline. They decided to switch back to finasteride, along with minoxidil, LLLT, and ketoconazole, due to dissatisfaction with dutasteride's results and side effects.

      community High Nicotine use and Hair Loss

      in Chat  76 upvotes 2 months ago
      Heavy nicotine use can lead to hair thinning and loss, but quitting can reverse these effects. The user noticed significant hair regrowth after quitting vaping.

      community Proof that finasteride messes with neurosteroids

      in Research/Science  230 upvotes 3 months ago
      Finasteride can impact neurosteroids, potentially causing depression and other side effects in some users. Despite these concerns, many continue using it for hair loss, with some switching to topical applications to mitigate side effects.