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GlossarySystemic Medications (Systemic Treatment)

drugs that affect the entire body via bloodstream

Systemic medications are drugs that work throughout the entire body rather than targeting a specific area. They are often taken orally or injected, allowing the active ingredients to enter the bloodstream and reach various tissues and organs. This type of treatment is commonly used for conditions that affect multiple parts of the body, such as autoimmune diseases or widespread infections.

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Tracking 8 products like 13 Lonitab 10 mg, 125 Polaris Research NR08 7%, 127 Polaris Research NR11 12% Minoxidil Sulfate, 171 Hyphoral 200mg and 252 Hair Solution Pyrilutamide Powder from by companies like AllDayChemist, Minoxidil Express, Inhouse Pharmacy and MV supplements . View all 8 products »

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community Most Recent Interesting Hairloss Studies: 10% Minox vs 5% Minox / Radio Rrequency Treatment for AA / Topical Ketoconazole / PRP+Minox vs Minox vs PRP / Alopecia as a systemic disease

in Treatment 92 upvotes 4 years ago

Treatments for hair loss, such as topical minoxidil, platelet-rich plasma therapy with or without minoxidil, ketoconazole, non-abative radio frequency, natural products, finasteride and cortexolone 17 alpha propionate. The post evaluates the efficacy and safety of these treatments in various studies.

community 15 months fin and keto, thinking about starting oral min. What’s the best way to get ahold of it?

in Progress Pictures 142 upvotes 1 year ago

The post discusses the user's successful hair regrowth after 15 months of using finasteride and ketoconazole. The user is considering starting oral minoxidil, but others suggest sticking with the current treatment or trying topical minoxidil instead.

community 2024 guide for male pattern baldness: 10 take home messages from Dr. Moreno-Arrones

in Research/Science 244 upvotes 1 month ago

Effective treatments for male pattern baldness include finasteride, dutasteride, and oral minoxidil. Non-effective approaches include oils, shampoos, serums, laser therapies, massages, vitamins, and microneedling.

community Evidenced Based Meta-Analyses and Systemic Reviews of Androgenic Alopecia and Treatments

in Research/Science 13 upvotes 4 years ago

Evidence-based treatments for androgenic alopecia, such as minoxidil, finasteride, low-level laser light therapy, dutasteride, platelet-rich plasma, and topical ketoconazole. It discusses the efficacy, safety, and mechanism of action of these treatments, as well as future developments in understanding this polygenic condition.

community New systematic review on topical and systemic spironolactone (2023)

in Research/Science 7 upvotes 1 year ago

Hair loss treatments discussed include Minoxidil, Finasteride, and RU58841. Topical and oral spironolactone show potential in improving hair growth when combined with topical Minoxidil.

community RU58841, Topical dutasteride minoxidil and tretonin, dermarolling, serioxyl, and redensyl for about 3 months. Each picture is about 2 weeks of growth. I used to have thick hair with big curls. Am I on track to get it back? Age 32

in Progress Pictures 25 upvotes 2 years ago

Treatments for hair loss, including topical dutasteride minoxidil, tretonin, dermarolling, serioxyl, and redensyl over a period of 3 months; switching from RU58841 to pyrilutamide was suggested with potentially less risk of systemic side effects; and encouragement to not give up hope.

community How is there no topical anti-androgen that doesn’t go systematic?!

in Treatment 6 upvotes 4 years ago

Hair loss treatments discussed include Minoxidil, Finasteride, RU58841, Alfatradiol, and Eucapil. Topical treatments must penetrate skin and may go systemic, with effectiveness varying.

community Any Topilutamide/Fluridil/Eucapil and/or topical Dutasteride experiences?

in Finasteride/Dutasteride 4 upvotes 5 months ago

The conversation discusses the effectiveness and systemic absorption of Topilutamide/Fluridil/Eucapil and topical Dutasteride for hair loss. Users are sharing their experiences and seeking success stories with these treatments.

community What makes breezula different than formula 82f?

in Question 9 upvotes 4 years ago

Breezula (clascoterone) and Formula 82F (topical finasteride) are treatments for hair loss that block DHT differently; Breezula competes with DHT at the hormone receptor site without systemic effects, while 82F inhibits the enzyme that converts testosterone to DHT. Breezula may work for those who don't respond to finasteride and vice versa.

community Topical Dutasteride and Mesotherapy Dutasteride: It Works

in Finasteride/Dutasteride 11 upvotes 11 months ago

Topical dutasteride with microneedling and mesotherapy dutasteride injections are effective treatments for androgenetic alopecia in both men and women. These methods offer promising alternatives to oral therapies with potentially fewer systemic side effects.

community Topical finasteride now the safest possible path?

in Finasteride/Dutasteride 72 upvotes 4 months ago

Topical finasteride is considered a safer option for hair regrowth with fewer systemic side effects compared to oral finasteride. Some users report similar efficacy and side effects between topical and oral treatments, while others prefer topical due to reduced systemic exposure.

community Topical Dutasteride & Microneedling Works

in Finasteride/Dutasteride 5 upvotes 2 months ago

Topical dutasteride, especially at higher concentrations, can be effective for hair loss when combined with microneedling to enhance absorption. Users discuss the side effects of finasteride and dutasteride, with some preferring topical treatments to avoid systemic side effects.

community Lowering DHT vs measured level and topical scalp treatment issues

in Research/Science 1 upvotes 8 months ago

The conversation discusses the effects of lowering DHT on hair loss and the importance of monitoring DHT levels during treatment. The user suggests that individual responses to DHT and hair loss treatments vary, and expresses a preference for topical treatments over oral medications due to concerns about systemic DHT reduction.

community Is there any new drug that looks promising ?

in Research/Science 25 upvotes 8 months ago

The conversation discusses GT20029, a drug in Phase II trials that targets androgen receptors with minimal systemic effects, and TDM-105795, a growth stimulant with a different mechanism than minoxidil that may revive papilla stem cells. Both are potential new treatments for hair loss.

community Insane MTF recovery 18 months blocking androgens

in Progress Pictures 145 upvotes 1 year ago

Hair loss recovery using estrogen and anti-androgen treatment for 18 months showed significant improvement. However, results vary and alternative treatments like RU58841 and Dutasteride may work without systemic feminization.

community Reminder that Kintors Pyrilutamide results will be out this month

in Treatment 178 upvotes 3 years ago

Kintor's Pyrilutamide results for hair loss treatment will be released soon. The treatment may replace current treatments like finasteride and minoxidil without systemic side effects.

community Kintor Phase 2 Results released KX-826 (pyrilutamide)

in Research/Science 449 upvotes 2 years ago

Kintor Pharmaceutical's Phase 2 results with the drug Pyrilutamide, a potential alternative to 5-ARI drugs like Finasteride and Dutasteride but without the side effects. It could be used in combination with other topical treatments such as Minoxidil. The safety of the drug has been demonstrated in 6 months of use, however there are still questions about long term efficacy and systemic absorption.

community Minoxidil, low dose Finasteride, Pyrilutamide, Derma Rolling, shampoo... Why?

in Research/Science 11 upvotes 1 year ago

The conversation is about a person's hair loss treatment regimen, which includes Minoxidil, low-dose Finasteride, Pyrilutamide, weekly use of a derma roller, and hair loss shampoo. They chose these treatments to minimize systemic effects and plan to share their results for others' benefit.

community Requesting Experiences: Topical Dutasteride - Liposomes vs. DMSO vs. Trichosol Results?

in Finasteride/Dutasteride 29 upvotes 3 years ago

The conversation discusses experiences with topical dutasteride for hair loss, comparing formulations from FUEClinic, MinoxidilMax, and Strut. Users share their results and side effects, with some preferring topical over oral treatments to minimize systemic absorption.

community Topical Dutasteride - Non-Hormonal, Side Effect Free 5ARI?

in Treatments 372 upvotes 3 months ago

Topical dutasteride is suggested as a low side-effect treatment for hair loss, with a proposed dose of 0.025% 1ml/day. It is considered better than finasteride due to its even inhibition of DHT isoforms and lower systemic absorption.

community New Treatments, and a Huge Group Buy with Lots of Research

in Research/Science 109 upvotes 1 year ago

A user is organizing a group buy for various compounds aimed at reversing hair loss and gray hair, and improving brain health and fat loss. The user has developed a treatment plan based on extensive research and is inviting others to participate, with the option to choose only the compounds they need.

community 2020 Hair and Scalp Treatments: A Clinical Guide (in Depth 350 Page Guide)

in Treatment 62 upvotes 4 years ago

Treatments for hair loss, including topical immunotherapy, regenerative treatments, laser and light-based therapies, oral supplements, intralesional steroids, and new drugs like finasteride and minoxidil.

community An updated, simple guide to the most effective hair loss treatments

193 upvotes 5 years ago

Effective treatments for hair loss, including Dutasteride, Finasteride, Minoxidil, Dermarolling, LLLT, PRP, Ketoconazole, and Scalp Massage. In addition, anti-inflammatory diets and stress management are recommended to maintain or regrow hair.

community Can we have a thread that summarizes all treatments options in addition to the big 3 which we have some evidence for, their mechanism of action and whether they can be combined with the big 3(other than dermarolling)?

in Treatment 55 upvotes 6 years ago

The conversation discusses hair loss treatments beyond the commonly known three, focusing on separating effective treatments from myths. Dutasteride and low-dose oral Minoxidil are mentioned as having clinical evidence for increasing hair counts, but with potential side effects.

community There are no new treatments as of now.

in Chat 2 years ago

Treatments for androgenic hair loss, including the use of finasteride, minoxidil, nizroal and microneedling/dermarolling. Side effects are discussed and it is noted that while there are tradeoffs to taking medications, they are generally safe and effective.

community Best hair loss treatments ranked: a complete guide

361 upvotes 5 years ago

Hair loss treatments, including Dutasteride 0.5mg daily, finasteride 1mg daily, minoxidil 5% 2x daily, dermarolling, low-level light therapy (LLLT), ketokonazole shampoo, and diet optimization; discussing their effectiveness and side effects.

community It’s crazy how it’s 2018 and the only hair loss treatments we have feature undesirable side effects and/or aren’t even effective for many people.

136 upvotes 6 years ago

Hair loss treatments, including minoxidil, dermarolling, finasteride, dutasteride, hair transplants, hair systems, and shaving the head. The conversation covers various opinions on these treatments and mentions possible side effects as well as alternatives like wigs, vitamins, and lifestyle changes. The post expresses disappointment that there has been no major breakthrough in the field of hair loss treatments despite decades of research.

community Reddit’s amatorial meta analysis of 17 already avaliable hair loss prevention treatments that were found to be effective in clinical studies but are not FDA approved for MPB. PROS and CONS. (2022 Guide if Finasteride and Minoxidil are not working/ give you sides/are not enough) 77 studies linked!

in Research/Science 586 upvotes 2 years ago

The post and conversation are about hair loss treatments that have been found to be effective in studies. There are 19 different treatments mentioned, including oral minoxidil, oral dutasteride, topical finasteride, RU58841, and more. The best treatment for an individual depends on factors like availability, cost, side effects, and personal preferences.

community Huge Group Buy is Now Live with New and Existing Treatments

in Product 146 upvotes 1 year ago

A group buy for hair loss treatments including Harmine 19a, TM5614, Abiraterone Acetate, and others. A compound, BMS-202, that can potentially reverse gray hair is also mentioned.

community How do we only have two treatments to combat hair loss at this point in time?

in Chat 211 upvotes 1 year ago

The post discusses frustration over the limited and not always effective treatments for hair loss, mainly Minoxidil and Finasteride. The conversation includes mentions of potential new treatments like GT20029, HMI-115, CosmeRNA, KX-826, and microneedling, but also highlights the challenges of funding and prioritizing research in this area.