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      community Anyone used CB-03-01 (clascoterone), is it worth it, too risky??

      in Research/Science  2 upvotes 7 months ago
      The user experienced side effects from low-dose topical finasteride and is considering using clascoterone (CB-03-01) despite concerns about its risks and cost. They seek advice on its effectiveness and potential side effects compared to other treatments like alfatradiol and fluridil.

      community Fun thought experiment about halting hair loss permamently

      in Research/Science  58 upvotes 7 months ago
      A user proposed genetically engineering scalp stem cells to stop androgen receptors from causing hair loss. Others discussed the feasibility, existing research, and potential issues with this approach, including targeting the correct cells and unintended effects.

      community F the big 3, it's just big me!

      in Satire  667 upvotes 7 months ago
      The conversation discusses hair loss treatments, with users mentioning dutasteride (Dut) as effective and wishing for more accessible dosages. They also debate the components of the "big 3" treatments, which now include Dut, RU58841, and oral minoxidil, with finasteride and minoxidil being consistently mentioned.

      community Microneedling doesnt seem to do anything

      in Microneedling  6 upvotes 8 months ago
      The user has been using finasteride for 2 years, nizoral for 1.5 years, topical minoxidil for 1 year, and microneedling for 3 months to treat hair loss but hasn't seen improvement or regrowth, even experiencing shedding with new treatments. They are concerned about continued thinning despite the treatments.

      community Small progress after 1 year 35m

      in Progress Pictures  184 upvotes 8 months ago
      A man saw improvement in hair loss after a year using 1mg finasteride daily and minoxidil twice daily, but reduced finasteride due to side effects. He switched to 0.5mg dutasteride daily, topical finasteride twice daily, microneedling weekly, and 2.5mg oral minoxidil, but may stop minoxidil due to chest pains.

      community Trying to regrow crown been on Fin for 4.5 years

      in Finasteride/Dutasteride  6 upvotes 8 months ago
      The user has been on finasteride for 4.5 years and minoxidil for 10 years, maintaining hair but not regrowing much on the crown and temples. They are considering using a dermastamp more frequently and possibly trying RU58841, but are hesitant about dutasteride due to concerns about side effects and DHT suppression.

      community So is GT20029 available on the grey market anywhere?

      in Treatment  16 upvotes 8 months ago
      The conversation discusses the availability of GT20029, a new topical hair loss treatment with fewer side effects than Minoxidil or finasteride. Users suggest using finasteride to preserve hair until GT20029 becomes available.

      community GT20029 China Phase II Trial For AGA Reached Primary Endpoint

      in Research/Science  134 upvotes 8 months ago
      The GT20029 tincture, a topical androgen receptor degrader, showed significant hair growth and good safety in a China Phase II trial for male androgenetic alopecia (AGA), with the 1% dose twice weekly identified as optimal. The company plans to initiate Phase III trials in China and Phase II in the U.S., and the treatment also shows promise for acne.

      community 1 year of min+fin+ketoconazole

      in Progress Pictures  1050 upvotes 8 months ago
      The user has been using minoxidil daily, finasteride three times a week, and ketoconazole 1-3 times a week for a year to treat hair loss, resulting in noticeable hair regrowth at the hairline and temples, with minor side effects like itching and dandruff. They started with minoxidil a month before the other treatments and experienced an initial shedding phase for about six weeks.

      community 3 months 7 days fin 0.5mg /Min and derma

      in Is this regrowth?  131 upvotes 9 months ago
      The user has been using finasteride (0.5mg), minoxidil (5% foam), dermarolling, and rosemary oil for 3 months, noticing baby hairs and some shedding. Advice given includes continuing the current treatment, considering additional treatments, and potentially increasing the finasteride dose.

      community My current nuclear stack. Thoughts?

      in Chat  6 upvotes 9 months ago
      The user is using RU58841 twice daily, dutasteride 0.5mg every two days, dutasteride mesotherapy every three months, and 20mg oral minoxidil daily. Other users suggest this regimen is excessive and recommend adding microneedling and ketoconazole shampoo.

      community Increasing Oral Minoxidil Dose Over Time

      in Research/Science  96 upvotes 9 months ago
      A user reports hair loss despite using minoxidil and plans to increase their oral minoxidil dose gradually while also taking finasteride, dermarolling weekly, and applying topical stemoxydine nightly. They shared a link suggesting that increasing minoxidil dosage can improve hair growth and thickness.

      community Creatine's effect on Hair Loss and DHT

      in Research/Science  103 upvotes 10 months ago
      A 21-year-old male managed to control his hair loss using Nizoral, RU58841, and finasteride, but experienced increased scalp itchiness after starting creatine, which subsided upon stopping creatine. Users shared mixed experiences on whether creatine affects hair loss, with some reporting negative effects and others seeing no change or defending its benefits.

      community 6 months aggressive treatment for hair loss

      in Progress Pictures  114 upvotes 10 months ago
      The user shared a 6-month aggressive hair loss treatment progress, using oral minoxidil, finasteride/minoxidil topical, dutasteride, derma stamping, Nizoral, and daily Cialis, which notably improved regrowth. Commenters observed significant improvement, with one noting a change from a Norwood 5 to a Norwood 1 in hair loss classification.

      community Combining all your topicals into one

      in Treatment  3 upvotes 10 months ago
      The user is using a hair loss treatment regimen that includes applying various topical solutions and taking oral medication. They are mixing their topical treatments to save time but are concerned about the effectiveness of the treatments when combined and stored.