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The GT20029 tincture, a topical androgen receptor degrader, showed significant hair growth and good safety in a China Phase II trial for male androgenetic alopecia (AGA), with the 1% dose twice weekly identified as optimal. The company plans to initiate Phase III trials in China and Phase II in the U.S., and the treatment also shows promise for acne.

Doctors often prescribe finasteride for hair loss without testing testosterone levels. There is no need for such tests before starting the medication.

The user shared a 7-year hair progress journey, starting with occasional minoxidil use and later including a finasteride prescription, online prescriptions, and microneedling. Significant hair growth was achieved, but side effects led to a reduction in medication dosage.

A video suggests 0.6mm microneedling is more effective for hair regrowth than 1.2mm, as it causes less trauma to stem cells. People commonly believe 1.5mm is best, but this may vary based on individual factors.

The user has been using minoxidil daily, finasteride three times a week, and ketoconazole 1-3 times a week for a year to treat hair loss, resulting in noticeable hair regrowth at the hairline and temples, with minor side effects like itching and dandruff. They started with minoxidil a month before the other treatments and experienced an initial shedding phase for about six weeks.

The user has been using oral finasteride and minoxidil with vitamins for 5 months and seen improvements. They are asking if adding topical minoxidil would be beneficial or if they should continue with the oral treatment alone.

A 31-year-old has been on finasteride for 8 years and is experiencing less dense hair and itchiness, and is considering adding minoxidil or RU58841 to their regimen. They are also inquiring about the benefits of oral versus topical finasteride.

The user has been using finasteride (0.5mg), minoxidil (5% foam), dermarolling, and rosemary oil for 3 months, noticing baby hairs and some shedding. Advice given includes continuing the current treatment, considering additional treatments, and potentially increasing the finasteride dose.

People discussed their experiences with anti-androgens for hair loss, mentioning side effects like chest pains with RU58841 and skepticism due to lack of safety data, while considering Fluridil as a potential addition to treatment. Some users expressed reluctance to use these chemicals.

The user is using RU58841 twice daily, dutasteride 0.5mg every two days, dutasteride mesotherapy every three months, and 20mg oral minoxidil daily. Other users suggest this regimen is excessive and recommend adding microneedling and ketoconazole shampoo.

The conversation discusses the effectiveness and safety of hair loss treatments, specifically RU58841 and Pyrilutimide (Pyril), with users sharing that Pyril was no more effective than a placebo and expressing concerns about the safety of RU58841 based on personal experiences and the lack of pharmaceutical interest.

A user reports hair loss despite using minoxidil and plans to increase their oral minoxidil dose gradually while also taking finasteride, dermarolling weekly, and applying topical stemoxydine nightly. They shared a link suggesting that increasing minoxidil dosage can improve hair growth and thickness.

A user shared their positive 6-month experience using Hims finasteride and minoxidil spray for hair loss, with others discussing the effectiveness and side effects of topical treatments. Instructions on how to use the spray were also provided.

The user is excited about an upcoming update for GT20029, expected in March. They express frustration with the negativity on Reddit.

A 21-year-old male managed to control his hair loss using Nizoral, RU58841, and finasteride, but experienced increased scalp itchiness after starting creatine, which subsided upon stopping creatine. Users shared mixed experiences on whether creatine affects hair loss, with some reporting negative effects and others seeing no change or defending its benefits.

The user shared a 6-month aggressive hair loss treatment progress, using oral minoxidil, finasteride/minoxidil topical, dutasteride, derma stamping, Nizoral, and daily Cialis, which notably improved regrowth. Commenters observed significant improvement, with one noting a change from a Norwood 5 to a Norwood 1 in hair loss classification.

Some users of RU-58841 report cardiovascular symptoms like heart palpitations and chest tightness, which may be linked to its metabolites causing lung disease. The safety of RU-58841 is uncertain due to lack of long-term data and concerns about product purity, especially from gray market sources.

The user shared progress pictures showing improvement in hair growth after one year of using finasteride and minoxidil. They are considering microneedling to further improve their hairline and have chosen to use a derma stamp.

The user is using a hair loss treatment regimen that includes applying various topical solutions and taking oral medication. They are mixing their topical treatments to save time but are concerned about the effectiveness of the treatments when combined and stored.

A 30-year-old male is considering using dutasteride and fluridil for hair loss maintenance and is curious about the effectiveness of topical spironolactone, as he cannot take finasteride. He is also planning a hair transplant.

The conversation discusses a user's two-month hair regrowth progress using Minoxidil and a 0.5mm dermaroller. Some suggest adding a 5-alpha-reductase inhibitor like finasteride or dutasteride to maintain the results.

The conversation is about frustration over the delay in phase 2 results for a hair loss treatment called GT20029. One user suspects the treatment may have failed.

A user experienced severe chest pains and shortness of breath after using RU58841 for hair loss and was advised by a doctor that blocking androgens can weaken the heart. They decided to continue with finasteride, minoxidil, and a hair transplant instead.

The user reports regrowth after 5 months using Minoxidil, finasteride, microneedling with a derma stamp, Nizoral shampoo, multivitamins, and biotin, and has shared progress pictures. They apply treatments daily, microneedle twice a week, and exercise regularly, noting an improvement in their mental well-being.

Oral minoxidil can cause skin issues like redness and bumps. The user saw no hair improvement with oral minoxidil but noticed increased facial hair.

A 19-year-old has seen hair regrowth after 10 months using finasteride and recently added minoxidil and tretinoin. They experienced no side effects from the treatments and are optimistic about further improvement.

The conversation discusses a transgender individual's successful hair loss treatment over 1.5 years using 2.5mg oral minoxidil, 5mg finasteride, and 8mg weekly injectable estradiol valerate. Some users debate the appropriateness of this approach within the group's goals, while others support the individualized treatment and its additional benefits for transgender individuals.

The conversation is about enhancing dermarolling for hair loss by using topical peptides like tb-500 or GHK-Cu to aid in healing and hair growth, and whether anyone has experienced significant results from this method.

The conversation discusses potential future hair loss treatments, including SCUBE3, hair follicle cloning, and GT20029, with mentions of past disappointments like CosmeRNA and hopes for treatments like Verteporfin for infinite donor hair.

The conversation is about a meme related to hair loss that influenced someone to start taking finasteride. Another person agrees that the meme accurately represents the situation.