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      community DHT Harms Scalp Microbiome: DHT Itch is REAL

       413 upvotes 1 year ago
      Increased Malassezia and Cutibacterium in the scalp microbiome are linked to higher sebum production and inflammation in androgenetic alopecia (AGA). Treatments include ciclopirox shampoo, benzoyl peroxide shampoo, clobetasol propionate, calcipotriol, minoxidil, finasteride, and dutasteride.

      community I cry every day, everything is very depressing

      in Finasteride/Dutasteride  52 upvotes 1 year ago
      A user is experiencing hair loss despite using dutasteride and oral minoxidil, feeling hopeless and considering a hair system. They are advised to try ketoconazole, seek a second opinion from a dermatologist, and consider treatments like finasteride, RU58841, and hair transplants.

      community Better Than Minoxidil? Topical Sodium Valproate

       50 upvotes 1 year ago
      Topical sodium valproate may promote hair growth by inhibiting GSK3β, allowing beta-catenin to proliferate, but it has potential side effects and requires more research. The conversation also mentions skepticism about a product called Vdphlo1, which includes sodium valproate and other ingredients.

      community My story (31 years old - male)

      in Progress Pictures  36 upvotes 1 year ago
      A 31-year-old male experienced hair thinning and initially used topical minoxidil, then switched to finasteride, which caused significant shedding. He later adopted a regimen of dutasteride, oral minoxidil, and anti-dandruff shampoo, leading to positive hair growth results, though he noted increased body hair as a side effect of oral minoxidil.

      community CRISPR Is Curing People Right Now. Genetic Hair Loss is Next?

       112 upvotes 1 year ago
      CRISPR shows promise for treating hair loss by targeting specific genes. Current treatments include Minoxidil and finasteride, but CRISPR could offer a more precise solution, though it is still expensive and in early stages.

      community Debunking Androgenetic Theory (Hair Transplants)

      in Research/Science  25 upvotes 2 years ago
      The post discusses a theory that hair regrowth after transplant is due to the angiogenesis process (new blood vessels forming), not because the transplanted hair is unaffected by DHT. The responses highlight the established belief in 'donor dominance' (the importance of the hair's origin in transplantation) and skepticism about the new theory.

      community Dermarolling is a bit sad innit?

      in Microneedling  232 upvotes 4 years ago
      Hair loss treatments discussed include dermarolling, minoxidil, finasteride, and RU58841. Some users find dermarolling sad, while others mention the complexity of biological systems and limited research funding for hair loss.

      community Serious Oral Minoxidil Side Effects

       30 upvotes 5 years ago
      A user experienced severe side effects, including heart-related symptoms, after increasing their oral minoxidil dosage to 5 mg, leading them to stop the medication and seek medical advice. Many users advised against high doses of oral minoxidil, suggesting anxiety as a possible cause, and recommended consulting a doctor or switching to topical treatments.

      community Why does this industry still revolve around 5-AR inhibitors?

       40 upvotes 5 years ago
      Hair loss treatments still rely heavily on minoxidil, finasteride, and RU58841, with little innovation. Future treatments like stem cell therapy and RNA technology show promise but are not yet available.

      community DHT Itch and Oily Scalp Explained (and how to fix it)

       90 upvotes 3 months ago
      Malassezia overgrowth can worsen oily scalp and inflammation, contributing to hair loss. Treatments include antifungal shampoos, C6/C8 MCT oil, low-dose isotretinoin, finasteride, and dutasteride.

      community KX-826 Phase 3 Results Are Out

       121 upvotes 6 months ago
      KX-826 shows promising results for hair growth with fewer side effects, offering an alternative to finasteride and minoxidil. Users discuss combining it with minoxidil, dermarolling, and Nizoral for improved results.

      community Oral minoxidl is very very powerful.

      in Chat  609 upvotes 6 months ago
      Oral minoxidil is more effective than topical minoxidil for hair regrowth but may cause side effects like heart issues and increased body hair. Combining it with finasteride is common for better results, though side effects vary.

      community 25 years on Finasteride and it's not working anymore.

       324 upvotes 6 months ago
      A 47-year-old has been using finasteride for 25 years for hair loss, but it's less effective now. Suggestions include switching to dutasteride, stopping anastrozole, and trying minoxidil, microneedling, and possibly TRT.

      community I have a theory about hair loss

      in Treatment 7 months ago
      Hair loss is often linked to inflammation and DHT, with treatments like finasteride, dutasteride, and minoxidil being effective for many. Natural remedies like turmeric and oils are discussed, but medications are generally seen as more reliable for managing genetic hair loss.

      community Do not switch from topical to oral minoxidil.

       778 upvotes 8 months ago
      Switching from topical to oral minoxidil caused prolonged hair shedding without regrowth, leading to the use of both topical and oral minoxidil with oral finasteride. Responses to these treatments vary, emphasizing the need for personalized approaches.

      community for anyone using saw palmetto oil

      in Research/Science  19 upvotes 8 months ago
      The conversation discusses using saw palmetto oil to reduce hair loss, with the user reporting decreased shedding but no regrowth yet. The user plans to try minoxidil and finasteride, noting previous success with minoxidil but concerns about its greasiness.

      community EssenGen 6-Plus with PG Results - 12 Weeks (Update 2)

       1192 upvotes 9 months ago
      Significant hair regrowth was achieved using EssenGen 6-Plus with 6% minoxidil and 0.05% finasteride, along with Nizoral shampoo, over 12 weeks. No side effects were experienced, highlighting the benefits of a low dose.

      community Sebum production even on dutasteride, and its relation to MPB.

      in Finasteride/Dutasteride  6 upvotes 9 months ago
      The conversation discusses managing hair loss and scalp issues, with users sharing experiences using treatments like dutasteride, finasteride, ketoconazole, sulfur soap, and topical anti-androgens. Suggestions include trying sulfur soap, scalp massages, spironolactone, and dietary changes to reduce sebum production and dandruff.

      community Quote from Pelage (PP-405) Spokesperson...

       122 upvotes 11 months ago
      Pelage is developing a topical hair follicle stem cell therapy, PP405, for non-scarring alopecias like androgenetic alopecia, with Phase III trials planned and a potential market launch by 2027. The treatment may not require continuous use after initial regrowth.

      community its possible! dont give up. Its never too late

      in Progress Pictures  272 upvotes 11 months ago
      A user shared their successful hair regrowth journey using finasteride, minoxidil, microneedling, and castor oil, highlighting the importance of persistence despite initial shedding. They reported no side effects and encouraged consistency in treatment.

      community 31M. Just diagnosed with androgenic alopecia. Fears of min.

       13 upvotes 11 months ago
      A 31-year-old man with androgenic alopecia is considering treatments like finasteride, minoxidil, and ketoconazole shampoo but is worried about finasteride's side effects. Users recommend starting with finasteride or dutasteride for DHT blocking, suggesting topical solutions to reduce side effects.

      community Blood Results (UPDATED) TOTAL T 1279 ng/dL- 2 Yrs on Fin / 1.5 Yrs on Dut

       9 upvotes 1 year ago
      The user has been using a hair loss treatment regimen including RU58841, minoxidil, and dutasteride, but still experiences hairline recession and fatigue despite high testosterone levels. They are considering adjusting their dutasteride dosage due to concerns about libido and energy levels.

      community Should I take creatine if Im on fin?

       9 upvotes 1 year ago
      Creatine is unlikely to worsen hair loss for those on finasteride, with no strong scientific evidence linking it to increased hair loss. Many users report no negative effects on hair while using creatine.

      community Topical Finasteride 2 year update

       933 upvotes 1 year ago
      The user reported significant improvement in hair quality and stability using topical finasteride for two years, without side effects. They later added minoxidil, which may have further enhanced hair quality.