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      community Dear RU58841 Users- How did it go?

      in Chat  4 upvotes 5 months ago
      RU58841 is used by some for hair loss when finasteride and minoxidil are ineffective. Users report mixed results, with some experiencing side effects like chest pain and mood changes.

      community Androgenetic alopecia is a skin disease: DHT-mediated skin disorders

       63 upvotes 2 years ago
      Dihydrotestosterone (DHT) impacts various skin conditions, including Androgenetic alopecia and seborrheic dermatitis, by causing overactivity in sebaceous glands. Topical medications Tacrolimus and Clobetasol can reduce these inflammatory conditions, and treatments like RU58841, Minoxidil, and Finasteride may also be beneficial.

      community Just started my first vial of fluridil

       4 upvotes 3 years ago
      Fluridil was discussed as a hair loss treatment, with some users experiencing side effects like lethargy and chest tightness. Users also mentioned other treatments like RU58841 and finasteride, with mixed opinions on their effectiveness.

      community Any positive responses for Diffuse Thinner with Retrograde using Fin/Min/Dut

       4 upvotes 1 year ago
      People with diffuse thinning and retrograde hair loss are discussing treatments like finasteride, minoxidil, and dutasteride, with some reporting improvements and others experiencing issues like scalp inflammation and increased sebum. Suggestions include addressing scalp inflammation, considering gut health, and possibly using topical antiandrogens or micro-needling.

      community RU58841 and Dutasteride: How do they interact?

       5 upvotes 3 years ago
      The user experienced accelerated hair loss with Dutasteride but saw slight regrowth after adding RU58841 and stemoxydine to their regimen, which also includes Finasteride and Minoxidil. They are uncertain whether to continue with the current combination or switch back to only Finasteride due to concerns about Dutasteride's effects.

      community What else can make hair more sensitive to DHT?

       17 upvotes 1 month ago
      Genetics, inflammation, poor scalp circulation, stress, thyroid issues, low iron, vitamin D deficiency, steroids, age, fungal infections, stress, and creatine can increase hair sensitivity to DHT. Treatments mentioned include dutasteride, minoxidil, and Kre Alkalyn Monohydrate.

      community Does anyone know the main driver for the efficacy of micro-needling?

       5 upvotes 1 year ago
      Microneedling may enhance hair loss treatment by increasing the effectiveness of topical minoxidil, especially for those lacking the necessary enzyme to activate it. It might also work by triggering growth factors and improving topical absorption.

      community Side effects after 7 months without overthinking it.

       20 upvotes 4 years ago
      A user experienced erectile issues after 7 months of using Finasteride and sought advice. Responses varied, with some suggesting breaks and others sharing similar side effects or dismissing concerns.

      community Feeling hopeless even on nuclear stack

       25 upvotes 7 months ago
      The user feels hopeless about hair loss despite using finasteride, dutasteride, minoxidil, and RU58841, and having a hair transplant. They are advised to maintain consistency in treatment, consider increasing dutasteride dosage, and explore topical solutions for better results.

      community Serenoa repens (Saw palmetto)

       3 upvotes 6 months ago
      Saw palmetto, a 5-alpha reductase inhibitor, caused unexpected side effects like breast changes and altered semen consistency, which resolved after stopping its use. Concerns about similar side effects with finasteride or dutasteride were expressed, and another user reported low libido and depression from saw palmetto.

      community Beneficial supplement (my experience)

       1 upvotes 8 months ago
      The user shares their experience with hair loss treatments, specifically finasteride, and discusses the side effects like lowered libido and motivation. They recommend trying tyrosine to counter these effects, noting it improved their libido and energy levels.

      community Microneedling-induced shedding after 5 months?

      in Progress Pictures  22 upvotes 10 months ago
      A user experienced significant hair loss after starting microneedling, despite using dutasteride and topical minoxidil. They are advised to consult a doctor as the shedding pattern is unusual and may indicate alopecia areata or other scalp conditions.

      community Oral Minoxidil - The Hyper-Responder Concept

       4 upvotes 10 months ago
      Minoxidil's effectiveness varies due to genetic differences in the SULT1A1 enzyme, affecting how well it converts to its active form, minoxidil sulfate. Hyper-responders may experience rapid hair growth and increased side effects, such as pericardial effusion, even at low doses.

      community second shed on dutasteride, but a woman

       2 upvotes 1 year ago
      A woman experiencing hormonal hair loss is on dutasteride and bicalutamide, which initially improved her hair, but she is now experiencing a second shedding phase with significant short hair loss. Despite normal hormone levels and no deficiencies, she is unsure if this shedding is normal and seeks advice.

      community "nuked libido" does that mean 0 erections or just less horny?

       5 upvotes 6 days ago
      The user discusses experiencing changes in libido and erections while on finasteride, noting that supplements like tongkat, citrulline, arginine, zinc, and vitamin D help maintain morning erections. Other users share varied experiences with finasteride, with some reporting reduced libido and weaker erections, while others notice no significant changes.

      community Experiencing cognitive effects while on Dutasteride

       5 upvotes 1 week ago
      The user experienced fatigue, brain fog, and dizziness after taking Dutasteride for hair loss, suspecting it might be a side effect. They plan to consult a doctor and get blood work done, while others in the conversation discuss potential cognitive effects and compare Dutasteride to Finasteride.

      community For those that have used anti androgens what is your experience?

       19 upvotes 2 years ago
      People discussed their experiences with anti-androgens for hair loss, mentioning side effects like chest pains with RU58841 and skepticism due to lack of safety data, while considering Fluridil as a potential addition to treatment. Some users expressed reluctance to use these chemicals.

      community concerns about starting minoxidil

       1 upvotes 5 years ago
      An 18-year-old woman experiencing hair loss due to stress, possible PCOS, and low vitamin D is concerned about starting 5% minoxidil foam, prescribed by her doctor, due to potential facial hair growth. She is also using a topical steroid for scalp sensitivity and pain.

      community Bleeding too much for other reasons

       7 upvotes 3 years ago
      The user experienced excessive bleeding during microneedling after consuming caffeine and THC, and is unsure if they should continue with the same routine. They are seeking advice on whether the bleeding is a cause for concern.

      community Scalp Biopsy Results - Almost 2 Years Dutasteride, Still Worsening

      in Update  24 upvotes 1 year ago
      Dutasteride and finasteride are not effectively stopping hair loss for some users, despite long-term use. Some are considering or using RU58841, pyrilutamide, and other treatments like microneedling, while also managing seborrheic dermatitis with diet and topical solutions.

      community Looks like I’m allergic to propylene glycol..

       4 upvotes 4 years ago
      The user is experiencing an allergic reaction to propylene glycol in Kirkland minoxidil and is considering switching to a foam version or a low-PG minoxidil solution. They are also contemplating oral minoxidil but are concerned about its long-term safety.

      community 2+ Years of Finasteride treatment - Stopped hair-loss, got regrowth, but

       24 upvotes 1 year ago
      The user experienced successful hair regrowth with Finasteride and Minoxidil but developed erectile dysfunction and abdominal pain, possibly due to medication or lifestyle changes. They plan to consult a urologist and consider adjusting medication or trying supplements like zinc, DIM, or boron.